Perifused precision-cut liver slice system for the study of hormone-regulated hepatic glucose metabolism.

[1]  V. Hruby,et al.  The rapid desensitization of glucagon-stimulated adenylate cyclase is a cyclic AMP-independent process that can be mimicked by hormones which stimulate inositol phospholipid metabolism. , 1987, The Biochemical journal.

[2]  V. Hruby,et al.  Activation of two signal-transduction systems in hepatocytes by glucagon , 1986, Nature.

[3]  A. J. Gandolfi,et al.  Dynamic organ culture of precision liver slices for in vitro toxicology. , 1985, Life sciences.

[4]  V. Hruby,et al.  Metabolic effects and cyclic AMP levels produced by glucagon, (1-N alpha-Trinitrophenylhistidine,12-homoarginine)glucagon and forskolin in isolated rat hepatocytes. , 1984, Biochimica et biophysica acta.

[5]  W. Hagopian,et al.  Receptor binding and cell-mediated metabolism of [125I]monoiodoglucagon by isolated canine hepatocytes. , 1984, The Journal of biological chemistry.

[6]  L. Orci,et al.  Binding, internalization, and lysosomal association of 125I-glucagon in isolated rat hepatocytes. A quantitative electron microscope autoradiographic study. , 1980, The Journal of clinical investigation.

[7]  P. Guzelian,et al.  PHENOTYPIC STABILITY OF ADULT RAT HEPATOCYTES IN PRIMARY MONOLAYER CULTURE * , 1980, Annals of the New York Academy of Sciences.

[8]  C. Krumdieck,et al.  A new instrument for the rapid preparation of tissue slices. , 1980, Analytical biochemistry.

[9]  V. Hruby,et al.  (Des-Histidine1) (Nϵ-phenylthiocarbamoyllysine12)-glucagon: Effects on glycogenolysis in perfused rat liver , 1980 .

[10]  M. Houslay,et al.  The activity of glucagon-stimulated adenylate cyclase from rat liver plasma membranes is modulated by the fluidity of its lipid environment. , 1978, The Biochemical journal.

[11]  N. Tolbert,et al.  A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. , 1978, Analytical biochemistry.

[12]  S. Sell,et al.  Growth state-dependent phenotypes of adult hepatocytes in primary monolayer culture. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[13]  M. Lin,et al.  Effects of GTP on binding of (3H) glucagon to receptors in rat hepatic plasma membranes. , 1977, The Journal of biological chemistry.

[14]  M. Birnbaum,et al.  Activation of protein kinase and glycogen phosphorylase in isolated rat liver cells by glucagon and catecholamines. , 1977, The Journal of biological chemistry.

[15]  J. Corbin,et al.  Studies on the alpha-andrenergic activation of hepatic glucose output. II. Investigation of the roles of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in the actions of phenylephrine in isolated hepatocytes. , 1976, The Journal of biological chemistry.

[16]  M. Ui,et al.  Lack of correlation between hormonal effects on cyclic AMP and glycogenolysis in rat liver. , 1976, Archives of biochemistry and biophysics.

[17]  H. Krebs Perfusion techniques in biochemistry , 1973 .

[18]  M. Johnson,et al.  The regulation of gluconeogenesis in isolated rat liver cells by glucagon, insulin, dibutyryl cyclic adenosine monophosphate, and fatty acids. , 1972, The Journal of biological chemistry.

[19]  L. Birnbaumer,et al.  Inactivation of glucagon by plasma membranes of rat liver. , 1972, The Journal of biological chemistry.

[20]  L. Birnbaumer,et al.  The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. 3. Binding of glucagon: method of assay and specificity. , 1971, The Journal of biological chemistry.

[21]  L. Birnbaumer,et al.  The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. IV. Effects of guanylnucleotides on binding of 125I-glucagon. , 1971, The Journal of biological chemistry.

[22]  L. Birnbaumer,et al.  The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action. , 1971, The Journal of biological chemistry.

[23]  L. Birnbaumer,et al.  The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. I. Properties. , 1971, The Journal of biological chemistry.

[24]  L. Birnbaumer,et al.  The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. II. Comparison between glucagon- and fluoride-stimulated activities. , 1971, The Journal of biological chemistry.

[25]  B. Brown,et al.  A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate. , 1971, The Biochemical journal.

[26]  A. Gilman A protein binding assay for adenosine 3':5'-cyclic monophosphate. , 1970, Proceedings of the National Academy of Sciences of the United States of America.

[27]  A. J. Gandolfi,et al.  Tissue slicing and culturing revisited , 1987 .

[28]  Peter F. Smith A NOVEL ORGAN CULTURE SYSTEM FOR THE STUDY OF HEPATOTOXICITY). , 1985 .

[29]  R. Roskoski [1] Assays of protein kinase , 1983 .

[30]  M. Houslay Mobile receptor and collision coupling mechanisms for the activation of adenylate cyclase by glucagon. , 1981, Advances in cyclic nucleotide research.

[31]  M. Roberfroid,et al.  Interference of chemicals with glycogen metabolism in isolated hepatocytes. , 1980, Toxicology.

[32]  H. Pitot,et al.  Fetal phenotypic expression by adult rat hepatocytes on collagen gel/nylon meshes. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[33]  R. Lovrien Manometric and Biochemical Techniques , 1973 .