Do high rates of empirical treatment undermine the potential effect of new diagnostic tests for tuberculosis in high-burden settings?

[1]  K. Dheda,et al.  Diagnostic accuracy of a urine lipoarabinomannan strip-test for TB detection in HIV-infected hospitalised patients , 2012, European Respiratory Journal.

[2]  K. Dheda,et al.  Accuracy and impact of Xpert MTB/RIF for the diagnosis of smear-negative or sputum-scarce tuberculosis using bronchoalveolar lavage fluid , 2013, Thorax.

[3]  K. Dheda,et al.  Sputum induction to aid diagnosis of smear-negative or sputum-scarce tuberculosis in adults in HIV-endemic settings , 2013, European Respiratory Journal.

[4]  Pinar Keskinocak,et al.  Improving patient flow in an obstetric unit , 2011, Health Care Management Science.

[5]  Y. Manabe,et al.  Clinical Predictors and Accuracy of Empiric Tuberculosis Treatment among Sputum Smear-Negative HIV-Infected Adult TB Suspects in Uganda , 2013, PloS one.

[6]  C. Leung,et al.  Supervised and induced sputum among patients with smear-negative pulmonary tuberculosis , 2008, European Respiratory Journal.

[7]  J. Salomon,et al.  Population Health Impact and Cost-Effectiveness of Tuberculosis Diagnosis with Xpert MTB/RIF: A Dynamic Simulation and Economic Evaluation , 2012, PLoS medicine.

[8]  L. Solari,et al.  Performance of an algorithm based on WHO recommendations for the diagnosis of smear‐negative pulmonary tuberculosis in patients without HIV infection , 2011, Tropical medicine & international health : TM & IH.

[9]  Federico Girosi,et al.  Reducing the global burden of tuberculosis: the contribution of improved diagnostics , 2006, Nature.

[10]  Anna Vassall,et al.  Rapid Diagnosis of Tuberculosis with the Xpert MTB/RIF Assay in High Burden Countries: A Cost-Effectiveness Analysis , 2011, PLoS medicine.

[11]  C. Whitty,et al.  'Smear-negative' pulmonary tuberculosis in a DOTS programme: poor outcomes in an area of high HIV seroprevalence. , 2001, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[12]  M. Joloba,et al.  Meta-analysis to compare the accuracy of GeneXpert, MODS and the WHO 2007 algorithm for diagnosis of smear-negative pulmonary tuberculosis , 2013, BMC Infectious Diseases.

[13]  K. Floyd,et al.  Xpert MTB/RIF for diagnosis of tuberculosis and drug-resistant tuberculosis: a cost and affordability analysis , 2012, European Respiratory Journal.

[14]  J. Chakaya,et al.  Performance of the 2007 WHO Algorithm to Diagnose Smear-Negative Pulmonary Tuberculosis in a HIV Prevalent Setting , 2012, PloS one.

[15]  H-H Lin,et al.  A modelling framework to support the selection and implementation of new tuberculosis diagnostic tools [State of the art series. Operational research. Number 8 in the series]. , 2011, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[16]  R. Dawson,et al.  Do adjunct TB tests, when combined with Xpert MTB/RIF, improve accuracy and the cost of diagnosis in a resource-poor setting? , 2011 .

[17]  L. Scott,et al.  Time to Treatment and Patient Outcomes among TB Suspects Screened by a Single Point-of-Care Xpert MTB/RIF at a Primary Care Clinic in Johannesburg, South Africa , 2013, PloS one.

[18]  Hsien-Ho Lin,et al.  Modelling the impacts of new diagnostic tools for tuberculosis in developing countries to enhance policy decisions , 2012, Health care management science.

[19]  K. Dheda,et al.  Comparison of two methods for acquisition of sputum samples for diagnosis of suspected tuberculosis in smear-negative or sputum-scarce people: a randomised controlled trial. , 2013, The Lancet. Respiratory medicine.

[20]  Grant Theron,et al.  Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial , 2014, The Lancet.

[21]  Morgan Evans,et al.  Performance of the new WHO diagnostic algorithm for smear‐negative pulmonary tuberculosis in HIV prevalent settings: a multisite study in Uganda , 2012, Tropical medicine & international health : TM & IH.

[22]  T. Cohen,et al.  The Prevalence and Drug Sensitivity of Tuberculosis among Patients Dying in Hospital in KwaZulu-Natal, South Africa: A Postmortem Study , 2010, PLoS medicine.

[23]  R. Walensky,et al.  The cost-effectiveness of routine tuberculosis screening with Xpert MTB/RIF prior to initiation of antiretroviral therapy: a model-based analysis , 2012, AIDS.

[24]  S. Egwaga,et al.  Potential utility of empirical tuberculosis treatment for HIV-infected patients with advanced immunodeficiency in high TB-HIV burden settings. , 2011, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[25]  R. Chaisson,et al.  Evaluation of the World Health Organization algorithm for the diagnosis of HIV-associated sputum smear-negative tuberculosis. , 2011, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[26]  E. Katabira,et al.  Validation in Uganda of the New WHO Diagnostic Algorithm for Smear-Negative Pulmonary Tuberculosis in HIV Prevalent Settings , 2011, Journal of acquired immune deficiency syndromes.

[27]  Morten Ruhwald,et al.  Point‐of‐care diagnosis of tuberculosis: Past, present and future , 2013, Respirology.

[28]  Diana M. Negoescu,et al.  Screening and Rapid Molecular Diagnosis of Tuberculosis in Prisons in Russia and Eastern Europe: A Cost-Effectiveness Analysis , 2012, PLoS medicine.

[29]  A. Van Deun,et al.  Xpert® MTB/RIF for national tuberculosis programmes in low-income countries: when, where and how? , 2011, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

[30]  Alimuddin Zumla,et al.  Multidrug‐resistant TB in Zambia: review of national data from 2000 to 2011 , 2013, Tropical medicine & international health : TM & IH.

[31]  Eduardo Gotuzzo,et al.  Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study , 2011, The Lancet.

[32]  K. Dheda,et al.  Can Point-of-Care Urine LAM Strip Testing for Tuberculosis Add Value to Clinical Decision Making in Hospitalised HIV-Infected Persons? , 2013, PloS one.

[33]  N. Dendukuri,et al.  Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults , 2014, The Cochrane database of systematic reviews.

[34]  Grant Theron,et al.  Do adjunct tuberculosis tests, when combined with Xpert MTB/RIF, improve accuracy and the cost of diagnosis in a resource-poor setting? , 2011, European Respiratory Journal.