论文信息 - Cancer sequencing unravels clonal evolution - 字舞流文

Cancer sequencing unravels clonal evolution

Characterization of tumor heterogeneity at the sequence level presents new challenges and opportunities for targeted therapies.

Carlos Caldas | C. Caldas

[1] Huanming Yang,et al. Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor , 2012, Cell.

[2] K. Anderson,et al. Genetic variegation of clonal architecture and propagating cells in leukaemia , 2011, Nature.

[3] Andrew Menzies,et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer , 2010, Nature.

[4] P. A. Futreal,et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. , 2012, The New England journal of medicine.

[5] P. Nowell. The clonal evolution of tumor cell populations. , 1976, Science.

[6] Irmtraud M. Meyer,et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers , 2012, Nature.

[7] Ryan D. Morin,et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution , 2009, Nature.

[8] J. Troge,et al. Tumour evolution inferred by single-cell sequencing , 2011, Nature.

[9] Huanming Yang,et al. Single-Cell Exome Sequencing and Monoclonal Evolution of a JAK2-Negative Myeloproliferative Neoplasm , 2012, Cell.

[10] M. Nowak,et al. Distant Metastasis Occurs Late during the Genetic Evolution of Pancreatic Cancer , 2010, Nature.