MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways

Abstract Summary MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes. Availability and Implementation MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/ Supplementary information Supplementary data are available at Bioinformatics online.

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