Insulin sensitivity increase after calcium supplementation and change in intraplatelet calcium and sodium–hydrogen exchange in hypertensive patients with Type 2 diabetes 1

Aims/hypothesis  To investigate the effect of oral calcium (Ca2+) supplementation on insulin sensitivity measured by the euglycaemic hyperinsulinaemic clamp, intraplatelet cationic concentration of Ca2+ ([Ca2+]i) and the transmembrane sodium–hydrogen exchanger (NHE) activity in erythrocytes in subjects with Type 2 diabetes and hypertension.

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