Frequency of Heterozygous and Homozygous Alphax1-Antitrypsin Deficiencies in Patients with Pulmonary Emphysema.

Excerpt Homozygous alpha1-antitrypsin deficiency is known to predispose to the development of pulmonary emphysema. Heterozygotes are not known to be so predisposed. In a study of the relatives of a...