Passive Vaping from Sub-Ohm Electronic Cigarette Devices

To investigate passive vaping due to sub-ohm electronic cigarettes (e-cigs), aerosol number size distribution measurements (6 nm–10 µm) were performed during volunteer-vaping sessions. E-liquids, with vegetable glycerin (VG) and propylene glycol (PG), with a VG/PG ratio of 50/50 (with nicotine) and 80/20 (without nicotine), were vaped with a double-coil, single aerosol exit hole at 25–80 W electric power, corresponding to 130–365 kW m−2 heat fluxes and with an octa-coil, four aerosol exit holes atomizers, at 50–150 W electric power, corresponding to 133–398 kW m−2 heat fluxes. At the lowest heat flux, lower particle number concentrations (NTot) were observed for the nicotine-liquid than for the nicotine-free liquid, also due to its higher content of PG, more volatile than VG. For the octa-coil atomizer, at 265 and 398 kW m−2, NTot decreased below the first-generation e-cig, whereas volume concentrations greatly increased, due to the formation of super micron droplets. Higher volume concentrations were observed for the 80/20 VG/PG liquid, because of VG vaporization and of its decomposition products, greater than for PG. For the double coil atomizer, increasing the electric power from 40 W (208 kW m−2) to 80 W (365 kW m−2) possibly led to a critical heat flow condition, causing a reduction of the number concentrations for the VG/PG 50/50 liquid, an increase for the 80/20 VG/PG liquid and a decrease of the volume concentrations for both of them. Coherently, the main mode was at about 0.1 µm on both metrics for both liquids. For the other tests, two main modes (1 and 2 µm) were observed in the volume size distributions, the latter becoming wider at 100 and 150 W (265 and 398 kW m−2), suggesting the increased emission of light condensable decomposition products. The lower aerosol emissions observed at 150 W than at 100 W suggest the formation of gas-phase decomposition products. The observation of low-count high-volume aerosols addresses the relevance of the volume metric upon measuring the second-hand concentration of the aerosols released by sub-ohm e-cigarettes.

[1]  Dingcai Cao,et al.  Electronic nicotine delivery systems (ENDS) cue reactivity in dual users: A combined analysis. , 2021, Drug and Alcohol Dependence.

[2]  N. Saliba,et al.  Carrier Solvents of Electronic Nicotine Delivery Systems Alter Pulmonary Surfactant , 2021, Chemical research in toxicology.

[3]  P. Talbot,et al.  Design features and elemental/metal analysis of the atomizers in pod-style electronic cigarettes , 2021, PloS one.

[4]  A. Bhatnagar,et al.  Cardiorespiratory and Immunologic Effects of Electronic Cigarettes , 2021, Current Addiction Reports.

[5]  P. Krebs,et al.  JUUL E-Cigarette Quit Attempts and Cessation Perceptions in College Student JUUL E-Cigarette Users , 2020, American journal of health promotion : AJHP.

[6]  Weiling Li,et al.  Particle size measurement of electronic cigarette aerosol with a cascade impactor , 2020, Aerosol Science and Technology.

[7]  Eon S. Lee,et al.  Effects of propylene glycol, vegetable glycerin, and nicotine on emissions and dynamics of electronic cigarette aerosols , 2020, Aerosol science and technology : the journal of the American Association for Aerosol Research.

[8]  C. McDonald,et al.  The Evolving Landscape of e-Cigarettes , 2020, Chest.

[9]  N. Saliba,et al.  Hot wires and film boiling: Another look at carbonyl formation in electronic cigarettes. , 2020, Chemical research in toxicology.

[10]  C. McDonald,et al.  The Evolving Landscape of Electronic Cigarettes: A systematic review of recent evidence. , 2020, Chest.

[11]  G. Ginsberg,et al.  E-cigarette, or vaping, product use associated lung injury (EVALI): case series and diagnostic approach. , 2019, The Lancet. Respiratory medicine.

[12]  P. Babál,et al.  E-Cigarettes and Cancer Risk , 2019, Cancer Prevention Research.

[13]  D. Dutta,et al.  Influence of the E-Cigarette Emission Profile by the Ratio of Glycerol to Propylene Glycol in E-Liquid Composition , 2019, ACS omega.

[14]  B. Ekstrand-Hammarström,et al.  The toxic potential of a fourth‐generation E‐cigarette on human lung cell lines and tissue explants , 2019, Journal of applied toxicology : JAT.

[15]  P. van de Borne,et al.  Fourth generation e-cigarette vaping induces transient lung inflammation and gas exchange disturbances: results from two randomized clinical trials , 2019, American journal of physiology. Lung cellular and molecular physiology.

[16]  N. Saliba,et al.  Carbon Monoxide and Small Hydrocarbon Emissions from Sub-ohm Electronic Cigarettes. , 2019, Chemical research in toxicology.

[17]  J. L. Regens,et al.  Electronic cigarette power affects count concentration and particle size distribution of vaping aerosol , 2018, PloS one.

[18]  P. Avino,et al.  Environmental Electronic Vape Exposure from Four Different Generations of Electronic Cigarettes: Airborne Particulate Matter Levels , 2018, International journal of environmental research and public health.

[19]  J. Zeaiter,et al.  Surface Chemistry of Electronic Cigarette Electrical Heating Coils: Effects of Metal Type on Propylene Glycol Thermal Decomposition. , 2018, Journal of analytical and applied pyrolysis.

[20]  D. Eaton,et al.  Public Health Consequences of e-Cigarette Use , 2018, JAMA internal medicine.

[21]  Pasquale Avino,et al.  Ultrafine particles in domestic environments: Regional doses deposited in the human respiratory system. , 2018, Environment international.

[22]  P. Avino,et al.  Second-hand smoke generated by combustion and electronic smoking devices used in real scenarios: Ultrafine particle pollution and age-related dose assessment. , 2017, Environment international.

[23]  N. Saliba,et al.  "Juice Monsters": Sub-Ohm Vaping and Toxic Volatile Aldehyde Emissions. , 2017, Chemical research in toxicology.

[24]  A. Colacci,et al.  E-cigarettes induce toxicological effects that can raise the cancer risk , 2017, Scientific Reports.

[25]  E. Soule,et al.  Electronic cigarettes: what are they and what do they do? , 2017, Annals of the New York Academy of Sciences.

[26]  R. Strongin,et al.  Solvent Chemistry in the Electronic Cigarette Reaction Vessel , 2017, Scientific Reports.

[27]  P. Pratte,et al.  A scattering methodology for droplet sizing of e-cigarette aerosols , 2016, Inhalation toxicology.

[28]  Yifang Zhu,et al.  Effects of design parameters and puff topography on heating coil temperature and mainstream aerosols in electronic cigarettes , 2016 .

[29]  Dieter Helm,et al.  Air Change Measurements Using Tracer Gases: Methods and Results. Significance of air change for indoor air quality , 2011 .

[30]  Cheol-Heon Jeong,et al.  Inter-Comparison of a Fast Mobility Particle Sizer and a Scanning Mobility Particle Sizer Incorporating an Ultrafine Water-Based Condensation Particle Counter , 2009 .

[31]  J. E. Scott,et al.  The Pulmonary Surfactant: Impact of Tobacco Smoke and Related Compounds on Surfactant and Lung Development , 2004, Tobacco induced diseases.

[32]  C. Junge.  Comments on `Concentration and Size Distribution Measurements of Atmospheric Aerosols and a Test of the Theory of Self-Preserving Size Distributions'. , 1969 .

[33]  K. T. Whitby,et al.  Concentration and Size Distribution Measurements of Atmospheric Aerosols and a Test of the Theory of Self-Preserving Size Distributions , 1967 .

[34]  S. Nukiyama.  The Maximum and Minimum Values of the Heat Q Transmitted from Metal to Boiling Water under Atmospheric Pressure , 1966 .

[35]  Sylvia S. Burwell.  E-Cigarette Use Among Youth and Young Adults : A Report of the Surgeon General , 2016 .

[36]  C Protano,et al.  [When science becomes technology: epistemological and ethical consequences of the Adduction]. , 2015, La Clinica terapeutica.

[37]  Electronic cigarettes (e‐cigarettes) , 2014, CA: a cancer journal for clinicians.

[38]  P. Avino,et al.  Regional Deposition of Submicrometer Aerosol in the Human Respiratory System Determined at 1-s Time Resolution of Particle Size Distribution Measurements , 2013 .

[39]  D. Jo,et al.  PULMONARY DRUG DELIVERY AS A VITAL ROUTE FOR DELIVERYING NANOPARTICLES - A REVIEW , 2013 .

[40]  J. Patil,et al.  Pulmonary drug delivery strategies: A concise, systematic review , 2012, Lung India : official organ of Indian Chest Society.

[41]  Alan Shivers Foust,et al.  Principles of unit operations , 1960 .