Regulation of Early Cartilage Destruction in Inflammatory Arthritis by Death Receptor 3

To investigate the role of death receptor 3 (DR‐3) and its ligand tumor necrosis factor–like molecule 1A (TL1A) in the early stages of inflammatory arthritis.

[1]  D. Ramji,et al.  Regulation of ADAMTS-1, -4 and -5 expression in human macrophages: Differential regulation by key cytokines implicated in atherosclerosis and novel synergism between TL1A and IL-17☆ , 2013, Cytokine.

[2]  D. Chang,et al.  Decoy receptor 3 suppresses RANKL-induced osteoclastogenesis via down-regulating NFATc1 and enhancing cell apoptosis. , 2013, Rheumatology.

[3]  I. Humphreys,et al.  The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T‐cell immunity , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[4]  C. Calder,et al.  An Essential Role for Death Receptor 3 in Experimental Autoimmune Uveoretinitis , 2012, Ocular immunology and inflammation.

[5]  J. Bradley,et al.  DR3 signaling protects against cisplatin nephrotoxicity mediated by tumor necrosis factor. , 2012, The American journal of pathology.

[6]  D. Chang,et al.  Decoy Receptor 3 Attenuates Collagen-induced Arthritis by Modulating T Cell Activation and B Cell Expansion , 2011, The Journal of Rheumatology.

[7]  A. Cunningham,et al.  Death receptor 3 is essential for generating optimal protective CD41 T‐cell immunity against Salmonella , 2011, European journal of immunology.

[8]  Zheng‐gang Liu,et al.  The Adaptor Protein TRADD Is Essential for TNF-Like Ligand 1A/Death Receptor 3 Signaling , 2011, The Journal of Immunology.

[9]  A. Szymanowski,et al.  Increased Levels of Leukocyte-Derived MMP-9 in Patients with Stable Angina Pectoris , 2011, PloS one.

[10]  T. Ślebioda,et al.  Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia , 2011, Mucosal Immunology.

[11]  Stephen R. Clark,et al.  Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection. , 2011, Blood.

[12]  S. Targan,et al.  Constitutive TL1A (TNFSF15) Expression on Lymphoid or Myeloid Cells Leads to Mild Intestinal Inflammation and Fibrosis , 2011, PloS one.

[13]  C. Hunter,et al.  Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[14]  R. Siegel,et al.  The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation , 2010, Mucosal Immunology.

[15]  T. Malek,et al.  Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation. , 2010, The Journal of clinical investigation.

[16]  G. Wilkinson,et al.  The TNF-Like Protein 1A–Death Receptor 3 Pathway Promotes Macrophage Foam Cell Formation In Vitro , 2010, The Journal of Immunology.

[17]  Simon A. Jones,et al.  Interferon-γ inhibits interleukin-1β-induced matrix metalloproteinase production by synovial fibroblasts and protects articular cartilage in early arthritis , 2010, Arthritis research & therapy.

[18]  S. Dunnett,et al.  Age-Dependent Maintenance of Motor Controland Corticostriatal Innervation by Death Receptor 3 , 2010, The Journal of Neuroscience.

[19]  J. Fikes,et al.  Role of TL1A in the Pathogenesis of Rheumatoid Arthritis1 , 2009, The Journal of Immunology.

[20]  P. Sfikakis,et al.  Circulating levels of TNF-like cytokine 1A (TL1A) and its decoy receptor 3 (DcR3) in rheumatoid arthritis. , 2008, Clinical immunology.

[21]  T. Ślebioda,et al.  The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis , 2008, The Journal of experimental medicine.

[22]  M. Teixeira,et al.  The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature. , 2008, Arthritis and rheumatism.

[23]  S. Targan,et al.  TL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation. , 2008, Gastroenterology.

[24]  E. Shevach,et al.  The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases. , 2008, Immunity.

[25]  E. Podack,et al.  Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation , 2008, The Journal of experimental medicine.

[26]  M. Scott,et al.  TL1A–DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease , 2008, The Journal of experimental medicine.

[27]  W. Min,et al.  TL1A both promotes and protects from renal inflammation and injury. , 2008, Journal of the American Society of Nephrology : JASN.

[28]  E. Lo,et al.  MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke , 2008, Stroke.

[29]  A. Fosang,et al.  ADAMTS-5: the story so far. , 2008, European cells & materials.

[30]  A. Howard,et al.  X-ray crystal structure of TNF ligand family member TL1A at 2.1A. , 2007, Biochemical and biophysical research communications.

[31]  A. Mantovani,et al.  Soluble TNF-Like Cytokine (TL1A) Production by Immune Complexes Stimulated Monocytes in Rheumatoid Arthritis1 , 2007, The Journal of Immunology.

[32]  Yanan Li,et al.  Death receptor‐3 mediates apoptosis in human osteoblasts under narrowly regulated conditions , 2006, Journal of cellular physiology.

[33]  F. Cominelli,et al.  Role of TL1A and its receptor DR3 in two models of chronic murine ileitis. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[34]  J. Tschopp,et al.  Interactions of Tumor Necrosis Factor (TNF) and TNF Receptor Family Members in the Mouse and Human* , 2006, Journal of Biological Chemistry.

[35]  L. Audoly,et al.  Neutrophil-derived leukotriene B4 is required for inflammatory arthritis , 2006, The Journal of experimental medicine.

[36]  Wan-Wan Lin,et al.  Differential regulation of interleukin-8 gene transcription by death receptor 3 (DR3) and type I TNF receptor (TNFRI). , 2005, Experimental cell research.

[37]  S. Chakrabarti,et al.  Regulation of matrix metalloproteinase‐9 release from IL‐8‐stimulated human neutrophils , 2005, Journal of leukocyte biology.

[38]  H. Ma,et al.  Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis , 2005, Nature.

[39]  B. Kwon,et al.  Involvement of TL1A and DR3 in induction of pro-inflammatory cytokines and matrix metalloproteinase-9 in atherogenesis. , 2005, Cytokine.

[40]  M. Mizuno,et al.  Deletion of the gene encoding CD59a in mice increases disease severity in a murine model of rheumatoid arthritis. , 2004, Arthritis and rheumatism.

[41]  K. Osawa,et al.  Death receptor 3 (DR3) gene duplication in a chromosome region 1p36.3: gene duplication is more prevalent in rheumatoid arthritis , 2004, Genes and Immunity.

[42]  P. Wei,et al.  TL1A-induced NF-κB Activation and c-IAP2 Production Prevent DR3-mediated Apoptosis in TF-1 Cells* , 2003, Journal of Biological Chemistry.

[43]  Shigeyoshi Itohara,et al.  The Role of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Antibody-Induced Arthritis , 2002, The Journal of Immunology.

[44]  P. Tomasec,et al.  UL40-mediated NK evasion during productive infection with human cytomegalovirus , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[45]  Jun Zhang,et al.  TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. , 2002, Immunity.

[46]  A. Thern,et al.  DR3 Regulates Negative Selection during Thymocyte Development , 2001, Molecular and Cellular Biology.

[47]  A. Thern,et al.  Genomic structure, expression, and chromosome mapping of the mouse homologue for the WSL-1 (DR3, Apo3, TRAMP, LARD, TR3, TNFRSF12) gene , 2001, Immunogenetics.

[48]  J. E. Park,et al.  Tumor necrosis factor receptor superfamily 12 may destabilize atherosclerotic plaques by inducing matrix metalloproteinases. , 2001, Japanese circulation journal.

[49]  Y. Okada,et al.  Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis , 2000, Annals of the rheumatic diseases.

[50]  M. Baiocchi,et al.  Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis. , 1999, Cytokine.

[51]  C. Liang,et al.  Human neutrophils secrete gelatinase B in vitro and in vivo in response to endotoxin and proinflammatory mediators. , 1999, American journal of respiratory cell and molecular biology.

[52]  P. Young,et al.  Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells. , 1997, Gene.

[53]  A. Gurney,et al.  A novel receptor for Apo2L/TRAIL contains a truncated death domain , 1997, Current Biology.

[54]  S. Edwards,et al.  Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis. , 1997, Immunology today.

[55]  J. Bell,et al.  LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[56]  D. Goeddel,et al.  A death-domain-containing receptor that mediates apoptosis , 1996, Nature.

[57]  A. Chinnaiyan,et al.  Signal Transduction by DR3, a Death Domain-Containing Receptor Related to TNFR-1 and CD95 , 1996, Science.

[58]  A. Koch,et al.  Expression of matrix metalloproteinase 9 (96-kd gelatinase B) in human rheumatoid arthritis. , 1996, Arthritis and rheumatism.

[59]  G. Nuovo,et al.  Markedly elevated serum MMP-9 (gelatinase B) levels in rheumatoid arthritis: a potentially useful laboratory marker. , 1996, Clinical immunology and immunopathology.

[60]  M. Smith,et al.  Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[61]  H. Koren,et al.  Constitutive and stimulated MCP-1, GRO alpha, beta, and gamma expression in human airway epithelium and bronchoalveolar macrophages. , 1994, The American journal of physiology.

[62]  M. Feldmann,et al.  Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[63]  Gary R. Grotendorst,et al.  Cloning and sequencing of a new gro transcript from activated human monocytes: expression in leukocytes and wound tissue , 1990, Molecular and cellular biology.

[64]  C. Brinckerhoff,et al.  Matrix metalloproteinases: role in arthritis. , 2006, Frontiers in bioscience : a journal and virtual library.

[65]  A. Ishida,et al.  Matrix metalloproteinase-9 release from human leukocytes. , 2003, Journal of investigational allergology & clinical immunology.

[66]  M. Feldmann,et al.  Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases. , 2003, Nature medicine.

[67]  J. Tschopp,et al.  TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95). , 1997, Immunity.

[68]  H. Koren,et al.  Constitutive and stimulated MCP-1, GROα, β, and γ expression in human airway epithelium and bronchoalveolar macrophages , 1994 .