Halogen atoms determine the inhibitory potency of halogenated bisphenol A derivatives on human and rat placental 11β-hydroxysteroid dehydrogenase 2.

[1]  C. Bridges,et al.  Transport and Toxicity of Methylmercury-Cysteine in Cultured BeWo Cells , 2021, International journal of molecular sciences.

[2]  Haolin Chen,et al.  Effects of Midazolam on the Development of Adult Leydig Cells From Stem Cells In Vitro , 2021, Frontiers in Endocrinology.

[3]  X. Qiu,et al.  Prenatal exposure to bisphenols and risk of preterm birth: Findings from Guangxi Zhuang birth cohort in China. , 2021, Ecotoxicology and environmental safety.

[4]  Philipp Steinbichl,et al.  Bisphenol A and its alternatives in Austrian thermal paper receipts, and the migration from reusable plastic drinking bottles into water and artificial saliva using UHPLC-MS/MS. , 2021, Chemosphere.

[5]  Oriol Vinyals,et al.  Highly accurate protein structure prediction with AlphaFold , 2021, Nature.

[6]  Silvia G. Inderbinen,et al.  Species-specific differences in the inhibition of 11β-hydroxysteroid dehydrogenase 2 by itraconazole and posaconazole. , 2020, Toxicology and applied pharmacology.

[7]  J. Chovelon,et al.  Aqueous photodecomposition of the emerging brominated flame retardant tetrabromobisphenol S (TBBPS). , 2020, Environmental pollution.

[8]  R. Ge,et al.  Bisphenols and Leydig Cell Development and Function , 2020, Frontiers in Endocrinology.

[9]  K. Tittmann,et al.  Low-barrier hydrogen bonds in enzyme cooperativity , 2019, Nature.

[10]  R. Dabeka,et al.  LC-MS/MS analysis of bisphenol S and five other bisphenols in total diet food samples , 2019, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[11]  P. Toutain,et al.  Oral Systemic Bioavailability of Bisphenol A and Bisphenol S in Pigs , 2019, Environmental health perspectives.

[12]  Pengyu Ji,et al.  Toxicological effects of bisphenol A exposure-induced cancer cells migration via activating directly integrin β1. , 2019, Chemosphere.

[13]  C. Marsit,et al.  The Role of Placental 11-Beta Hydroxysteroid Dehydrogenase Type 1 and Type 2 Methylation on Gene Expression and Infant Birth Weight1 , 2015, Biology of reproduction.

[14]  Hong-Gang Ni,et al.  HBCD and TBBPA in particulate phase of indoor air in Shenzhen, China. , 2013, The Science of the total environment.

[15]  J. Seckl,et al.  11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action. , 2013, Physiological reviews.

[16]  R. Reynolds.  Glucocorticoid excess and the developmental origins of disease: Two decades of testing the hypothesis – 2012 Curt Richter Award Winner , 2013, Psychoneuroendocrinology.

[17]  R. Ge,et al.  Inhibition of human and rat 11β-hydroxysteroid dehydrogenases activities by bisphenol A. , 2012, Toxicology letters.

[18]  Andrew G. Leach,et al.  Free-Wilson and structural approaches to co-optimizing human and rodent isoform potency for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors. , 2012, Journal of medicinal chemistry.

[19]  Q. Lian,et al.  Environmental inhibitors of 11β-hydroxysteroid dehydrogenase type 2. , 2011, Toxicology.

[20]  J. Seckl,et al.  Glucocorticoids, prenatal stress and the programming of disease , 2011, Hormones and Behavior.

[21]  C. D. de Wit,et al.  Brominated flame retardants in the Arctic environment--trends and new candidates. , 2010, The Science of the total environment.

[22]  J. Seckl,et al.  Altered placental function of 11beta-hydroxysteroid dehydrogenase 2 knockout mice. , 2009, Endocrinology.

[23]  B. Frey,et al.  Prematurity Is Related to High Placental Cortisol in Preeclampsia , 2009, Pediatric Research.

[24]  J. M. Snyder,et al.  Reduction of glucocorticoid receptor ligand binding by the 11-β hydroxysteroid dehydrogenase type 2 inhibitor, Thiram , 2006, Steroids.

[25]  D. Hardy,et al.  11{beta}-Hydroxysteroid dehydrogenase 2 in rat leydig cells: its role in blunting glucocorticoid action at physiological levels of substrate. , 2005, Endocrinology.

[26]  A. Odermatt,et al.  Inhibition of 11β-hydroxysteroid dehydrogenase type 2 by dithiocarbamates , 2003 .

[27]  Igor V. Tetko,et al.  Prediction of n-Octanol/Water Partition Coefficients from PHYSPROP Database Using Artificial Neural Networks and E-State Indices , 2001, J. Chem. Inf. Comput. Sci..

[28]  J. Dötsch,et al.  The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2001 by The Endocrine Society Decreased Gene Expression of 11�-Hydroxysteroid Dehydrogenase Type 2 and 15-Hydroxyprostaglandin Dehydrogenase in Human Placenta of Patients , 2000 .

[29]  M. Kilby,et al.  11Beta-hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction. , 1998, Human reproduction.

[30]  C. Edwards,et al.  Inhibition of 11-beta-hydroxysteroid dehydrogenase in pregnant rats and the programming of blood pressure in the offspring. , 1996, Hypertension.

[31]  J. Funder,et al.  Substrate and inhibitor specificity of the cloned human 11 beta-hydroxysteroid dehydrogenase type 2 isoform. , 1996, The American journal of physiology.

[32]  W. Pangborn,et al.  Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution. , 1995, Structure.

[33]  J M Thornton,et al.  LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions. , 1995, Protein engineering.

[34]  OUP accepted manuscript , 2021, Nucleic Acids Research.

[35]  R. J. Doerksen,et al.  Topological polar surface area: a useful descriptor in 2D-QSAR. , 2009, Current medicinal chemistry.

[36]  Brian K. Shoichet,et al.  ZINC - A Free Database of Commercially Available Compounds for Virtual Screening , 2005, J. Chem. Inf. Model..

[37]  H. Guan,et al.  Cadmium reduces 11-hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells , 2005 .

[38]  H. Sasano,et al.  11Beta-hydroxysteroid dehydrogenase type II and mineralocorticoid receptor in human placenta. , 2000, The Journal of clinical endocrinology and metabolism.

[39]  D. Herschlag,et al.  Hydrogen bonding in enzymatic catalysis: analysis of energetic contributions. , 1999, Methods in enzymology.