ANALOGS OF 2′,5′-OLIGOADENYLATES: BIOLOGICAL PROBES FOR THE ANTIVIRAL/ANTITUMOR STATE OF MAMMALIAN CELLS1

[1]  P. Doetsch,et al.  Inhibition of Epstein-Barr virus-associated nuclear antigen (EBNA) induction by (2',5')oligoadenylate and the cordycepin analog: mechanism of action for inhibition of EBV-induced transformation. , 1982, Virology.

[2]  J. V. van Boom,et al.  2'-5'-Linked oligo(adenylic acid) and its analogs. A new class of inhibitors of mRNA methylation. , 1982, The Journal of biological chemistry.

[3]  T. Nilsen,et al.  Synthesis of (2'-5')oligoadenylate and activation of an endoribonuclease in interferon-treated HeLa cells infected with reovirus , 1982, Journal of virology.

[4]  M. Hershfield,et al.  Mechanism of deoxyadenosine-induced catabolism of adenine ribonucleotides in adenosine deaminase-inhibited human T lymphoblastoid cells. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[5]  J. Justesen,et al.  Regulation of 2-5 A synthetase activity and antiviral state in interferon treated chick cells. , 1982, Biochemical and biophysical research communications.

[6]  I. Kerr,et al.  Virus-mediated inhibition of the ppp(A2'p)nA system and its prevention by interferon. , 1982, Biochemical and biophysical research communications.

[7]  P. Lengyel.  Biochemistry of interferons and their actions. , 1982, Annual review of biochemistry.

[8]  A. Kimchi,et al.  Antimitogenic effects of interferon and (2′–5′)‐oligoadenylate in synchronized 3T3 fibroblasts , 1981, FEBS letters.

[9]  J. Mosca,et al.  Core (2'-5')oligoadenylate and the cordycepin analog: inhibitors of Epstein--Barr virus-induced transformation of human lymphocytes in the absence of interferon. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[10]  T. Nilsen,et al.  Double-stranded RNA causes synthesis of 2',5'-oligo(A) and degradation of messenger RNA in interferon-treated cells. , 1981, The Journal of biological chemistry.

[11]  P. Lengyel,et al.  Interferon action: RNA cleavage pattern of a (2'-5')oligoadenylate--dependent endonuclease. , 1981, Science.

[12]  P. Doetsch,et al.  Synthesis and characterization of (2′-5′)ppp3′dA(p3′dA)n, an analogue of (2′-5′)pppA(pA)n , 1981, Nature.

[13]  D. Niethammer,et al.  Interferon-neutralizing antibodies in a patient treated with human fibroblast interferon , 1981, Nature.

[14]  J. Skehel,et al.  Interferon action—sequence specificity of the ppp(A2′p)nA-dependent ribonuclease , 1981, Nature.

[15]  P. Karran,et al.  Hypoxanthine in deoxyribonucleic acid: generation by heat-induced hydrolysis of adenine residues and release in free form by a deoxyribonucleic acid glycosylase from calf thymus. , 1980, Biochemistry.

[16]  I. Kerr,et al.  Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells , 1980, Nature.

[17]  P. Lengyel,et al.  Synthesis of (2'-5')(A)n from ATP. Characteristics of the reaction catalyzed by (2'-5')(A)n synthetase purified from mouse Ehrlich ascites tumor cells treated with interferon. , 1980, The Journal of biological chemistry.

[18]  N. M. Kredich.  Inhibition of nucleic acid methylation by cordycepin. In vivo synthesis of S-3'-DEOXYADENOSYLMETHIONINE BY WI-L2 human lymphoblasts. , 1980, The Journal of biological chemistry.

[19]  J. Justesen,et al.  Elongation mechanism and substrate specificity of 2',5'-oligoadenylate synthetase. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[20]  C. Baglioni,et al.  Mechanism of pppA(2'p5'A)n2'p5'AOH synthesis in extracts of interferon-treated HeLa cells. , 1980, The Journal of biological chemistry.

[21]  W. Pfleiderer,et al.  Synthesis and properties of 3′-deoxyadenylate trimer dA2′p5′A2′p5′A , 1981 .

[22]  A. Kimchi,et al.  Regulation of lymphocyte mitogenesis by (2′–5′) oligo-isoadenylate , 1979, Nature.

[23]  I. Kerr,et al.  Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells , 1979, Nature.

[24]  J. Marx.  Interferon (I): on the threshold of clinical application. , 1979, Science.

[25]  C. Baglioni.  Interferon-induced enzymatic activities and their role in the antiviral state , 1979, Cell.

[26]  T. Haskell,et al.  Prodrugs of 9-(beta-D-arabinofuranosyl)adenine 2. Synthesis and evaluation of a number of 2',3'- and 3',5'-di-O-acyl derivatives. , 1979, Journal of medicinal chemistry.

[27]  T. Haskell,et al.  Prodrugs of 9-beta-D-arabinofuranosyladenine. 1. Synthesis and evaluation of some 5'-(O-acyl) derivatives. , 1978, Journal of Medicinal Chemistry.

[28]  R. I. Glazer,et al.  Cordycepin and xylosyladenine: inhibitors of methylation of nuclear RNA. , 1978, Biochemical and biophysical research communications.

[29]  K. Cantell.  Towards the clinical use of interferon. , 1978, Endeavour.

[30]  I. Kerr,et al.  Synthesis of low molecular weight inhibitor of protein synthesis with enzyme from interferon-treated cells , 1977, Nature.

[31]  M. Smulson,et al.  ADP-ribosylation of isolated nuclei from HeLa cells, rat liver, fetal rat liver, and Novikoff hepatoma. Effect of nicotinamide adenine dinucleotide analogs on template activity for DNA synthesis, incorporation into nuclear proteins, and a new 1''-3' osidic linkage. , 1977, The Journal of biological chemistry.

[32]  R. Baur,et al.  Role of adenine ring and adenine ribose of nicotinamide adenine dinucleotide in binding and catalysis with alcohol, lactate, and glyceraldehyde-3-phosphate dehydrogenases. , 1977, The Journal of biological chemistry.

[33]  W. Jelinek,et al.  3'-Terminal addition to HeLa cell nuclear and cytoplasmic poly (A). , 1977, Journal of molecular biology.

[34]  J. G. Cory,et al.  Incorporation of cordycepin (3'-deoxyadenosine) into ribonucleic acid and deoxyribonucleic acid of human tumor cells. , 1965, Biochimica et biophysica acta.

[35]  S. A. Hutchinson,et al.  508. Cordycepin, a metabolic product from cultures of Cordyceps militaris(Linn.) link. Part I. Isolation and characterisation , 1951 .