Homocysteine metabolism in cardiovascular cells and tissues: implications for hyperhomocysteinemia and cardiovascular disease.

[1]  J. Sambrook,et al.  Molecular Cloning: A Laboratory Manual , 2001 .

[2]  D. Jacobsen Homocysteine and vitamins in cardiovascular disease. , 1998, Clinical chemistry.

[3]  E. Tuzcu,et al.  High homocysteine, low folate, and low vitamin B6 concentrations: prevalent risk factors for vascular disease in heart transplant recipients. , 1998, Transplantation.

[4]  J. Witteman,et al.  Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC Group. , 1998, Circulation.

[5]  Č. Vlček,et al.  Identification and tissue distribution of human cystathionine beta-synthase mRNA isoforms. , 1998, Archives of biochemistry and biophysics.

[6]  S. Sunden,et al.  Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene. , 1997, Archives of biochemistry and biophysics.

[7]  M. Manning,et al.  Secondary structure of recombinant human cystathionine beta-synthase in aqueous solution: effect of ligand binding and proteolytic truncation. , 1997, Archives of biochemistry and biophysics.

[8]  A. Bostom,et al.  Hyperhomocysteinemia in end-stage renal disease: prevalence, etiology, and potential relationship to arteriosclerotic outcomes. , 1997, Kidney international.

[9]  J. Witteman,et al.  Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. , 1997, JAMA.

[10]  M. Kutner,et al.  Hyperhomocysteinemia confers an independent increased risk of atherosclerosis in end-stage renal disease and is closely linked to plasma folate and pyridoxine concentrations. , 1996, Circulation.

[11]  T. Garrow Purification, Kinetic Properties, and cDNA Cloning of Mammalian Betaine-Homocysteine Methyltransferase* , 1996, The Journal of Biological Chemistry.

[12]  S. Vollset,et al.  Homocysteine and Cardiovascular Disease , 1996, The Journal of the American Board of Family Medicine.

[13]  K. Robinson,et al.  Homocysteine and coronary atherosclerosis. , 1996, Journal of the American College of Cardiology.

[14]  R. Paroni,et al.  Prevalence of Moderate Hyperhomocysteinemia in Patients with Early-Onset Venous and Arterial Occlusive Disease , 1995, Annals of Internal Medicine.

[15]  David P Miller,et al.  Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease. , 1995, Circulation.

[16]  G. Omenn,et al.  A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. , 1995, JAMA.

[17]  P. Kamoun,et al.  Genomic organization of the human cystathionine beta-synthase gene: evidence for various cDNAs. , 1995, Biochemical and biophysical research communications.

[18]  R. Rodeheffer,et al.  Increase in total plasma homocysteine concentration after cardiac transplantation. , 1995, Mayo Clinic proceedings.

[19]  J. Kraus,et al.  Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein. , 1994, The Journal of biological chemistry.

[20]  J. Kraus,et al.  Expression of human cystathionine beta-synthase in Escherichia coli: purification and characterization. , 1994, Protein expression and purification.

[21]  M. Swaroop,et al.  Human cystathionine beta-synthase cDNA: sequence, alternative splicing and expression in cultured cells. , 1993, Human molecular genetics.

[22]  L. Chambless,et al.  Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. The Atherosclerosis Risk in Communities Study. , 1993, Circulation.

[23]  D. Wilcken,et al.  Homocysteine catabolism: levels of 3 enzymes in cultured human vascular endothelium and their relevance to vascular disease. , 1992, Atherosclerosis.

[24]  M. Swaroop,et al.  Rat cystathionine beta-synthase. Gene organization and alternative splicing. , 1992, The Journal of biological chemistry.

[25]  B. Norrving,et al.  Hyperhomocysteinaemia in stroke: prevalence, cause, and relationships to type of stroke and stroke risk factors , 1992, European journal of clinical investigation.

[26]  D. Wilcken,et al.  Betaine:homocysteine methyltransferase--a new assay for the liver enzyme and its absence from human skin fibroblasts and peripheral blood lymphocytes. , 1991, Clinica chimica acta; international journal of clinical chemistry.

[27]  D. Weir,et al.  Betaine-homocysteine methyltransferase: organ distribution in man, pig and rat and subcellular distribution in the rat. , 1991, Clinical science.

[28]  J. Finkelstein,et al.  Methionine metabolism in mammals. , 1990, The Journal of nutritional biochemistry.

[29]  M. Malinow,et al.  Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke. , 1990, Stroke.

[30]  M. Malinow,et al.  Homocyst(e)inemia in daily practice: levels in coronary artery disease , 1990 .

[31]  J. Kraus,et al.  Biosynthesis and proteolytic activation of cystathionine beta-synthase in rat liver. , 1984, The Journal of biological chemistry.

[32]  J. Kraus,et al.  Cystathionine beta-synthase from human liver: improved purification scheme and additional characterization of the enzyme in crude and pure form. , 1983, Archives of biochemistry and biophysics.

[33]  A. Pick,et al.  Activation of cystathionine synthase by adenosylmethionine and adenosylethionine. , 1975, Biochemical and biophysical research communications.

[34]  J. Finkelstein,et al.  Methionine metabolism in mammals: regulatory effects of S-adenosylhomocysteine. , 1974, Archives of biochemistry and biophysics.

[35]  M. Seashore,et al.  Studies of the Mechanism of Pyridoxine-Responsive Homocystinuria , 1972, Pediatric Research.

[36]  S. Mudd,et al.  Cystathionine Synthase in Tissue Culture Derived from Human Skin: Enzyme Defect in Homocystinuria , 1968, Science.

[37]  J. Finkelstein,et al.  Transsulfuration in mammals. Microassays and tissue distributions of three enzymes of the pathway. , 1965, The Journal of biological chemistry.

[38]  J. Finkelstein,et al.  Homocystinuria: An Enzymatic Defect , 1964, Science.

[39]  T. Gerritsen,et al.  The identification of homocystine in the urine. , 1962, Biochemical and biophysical research communications.

[40]  D. W. Neill,et al.  Metabolic Abnormalities Detected in a Survey of Mentally Backward Individuals in Northern Ireland , 1962, Archives of disease in childhood.

[41]  L. W. Butz,et al.  THE FORMATION OF A HOMOLOGUE OF CYSTINE BY THE DECOMPOSITION OF METHIONINE WITH SULFURIC ACID , 1932 .

[42]  P. Sarkar,et al.  Regulation of actin and tubulin gene expression by thyroid hormone during rat brain development. , 1996, Brain research. Molecular brain research.

[43]  S. Mudd Disorders of transsulfuration , 1989 .

[44]  J. Kraus Cystathionine β-synthase (human) , 1987 .

[45]  D. Cox,et al.  Structural and functional conservation of the human and yeast genes , 2022 .