Posterior fossa syndrome after surgical removal of a pineal gland tumor.

Posterior fossa syndrome, characterized by oromotor or oculomotor apraxia, emotional lability, and mutism, occurs in some children after infratentorial tumor resection, and is thought to involve injury to the dentatothalamocortical tract. Previous cases of posterior fossa syndrome involved pediatric patients with cerebellar and other posterior fossa tumors. To heighten awareness that posterior fossa syndrome can occur after resections of tumors in other neuroanatomic locations, we present a 16-year-old boy who developed this syndrome after surgical removal of a supratentorial pinealoma, and we include a discussion of his self-reported signs.

[1]  F. Gilles,et al.  Case series: acute mood symptoms associated with posterior fossa lesions in children. , 2004, The Journal of neuropsychiatry and clinical neurosciences.

[2]  A. Diamond.  Close interrelation of motor development and cognitive development and of the cerebellum and prefrontal cortex. , 2000, Child development.

[3]  R. Hales,et al.  J Neuropsychiatry Clin Neurosci , 1992 .

[4]  J. Sheehan,et al.  Cerebellar mutism in adults after posterior fossa surgery: a report of 2 cases. , 2005, Surgical neurology.

[5]  J. Schmahmann,et al.  The cerebellar cognitive affective syndrome. , 1998, Brain : a journal of neurology.

[6]  T. Baram,et al.  Cerebellar mutism in children: report of six cases and potential mechanisms. , 1995, Pediatric neurology.

[7]  M R Gaab,et al.  Neuroendoscopic approach to intraventricular lesions. , 1999, Neurosurgical focus.

[8]  P. Paquier,et al.  Postoperative motor speech production in children with the syndrome of 'cerebellar' mutism and subsequent dysarthria: a critical review of the literature. , 2007, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

[9]  P. Paquier,et al.  Tumour type and size are high risk factors for the syndrome of “cerebellar” mutism and subsequent dysarthria , 1999, Journal of neurology, neurosurgery, and psychiatry.

[10]  Amar Gajjar,et al.  Proximal dentatothalamocortical tract involvement in posterior fossa syndrome. , 2009, Brain : a journal of neurology.