New Strategies in Sarcoma Therapy: Linking Biology and Novel Agents
暂无分享,去创建一个
[1] D. Hawkins,et al. Rhabdomyosarcoma: Review of the Children's Oncology Group (COG) soft‐tissue Sarcoma committee experience and rationale for current COG studies , 2012, Pediatric blood & cancer.
[2] Andrew H. Beck,et al. ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour , 2012, The Journal of pathology.
[3] M. Lim,et al. Efficacy of crizotinib in children with relapsed/refractory ALK-driven tumors including anaplastic large cell lymphoma and neuroblastoma: A Children's Oncology Group phase I consortium study. , 2012 .
[4] J. Blay,et al. Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial , 2012, The Lancet.
[5] Arul M Chinnaiyan,et al. PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma. , 2012, Cancer research.
[6] Aki Vehtari,et al. One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial. , 2012, JAMA.
[7] Kevin B. Jones,et al. Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics. , 2012, Cancer cell.
[8] S. Ramaswamy,et al. Systematic identification of genomic markers of drug sensitivity in cancer cells , 2012, Nature.
[9] J. Borgia,et al. Targeting the insulin-like growth factor receptor pathway in lung cancer: problems and pitfalls , 2012, Therapeutic advances in medical oncology.
[10] C. Weldon,et al. Pediatric gastrointestinal stromal tumor. , 2012, Seminars in pediatric surgery.
[11] P. Casali,et al. A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.
[12] H. Joensuu,et al. The management of gastrointestinal stromal tumors: a model for targeted and multidisciplinary therapy of malignancy. , 2012, Annual review of medicine.
[13] C. Sander,et al. Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas. , 2011, Cancer discovery.
[14] D. Reinke,et al. R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[15] U. Dirksen,et al. Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcoma. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] K. Flaherty,et al. Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer , 2011, Clinical Cancer Research.
[17] Marc Ladanyi,et al. Advances in sarcoma genomics and new therapeutic targets , 2011, Nature Reviews Cancer.
[18] P. Casali,et al. Sunitinib in advanced alveolar soft part sarcoma: evidence of a direct antitumor effect. , 2011, Annals of oncology : official journal of the European Society for Medical Oncology.
[19] C. Rudin,et al. Brivanib (BMS-582664) in advanced soft-tissue sarcoma (STS): Biomarker and subset results of a phase II randomized discontinuation trial. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[20] Divya Pathania,et al. Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update. , 2011, Current pharmaceutical design.
[21] D. Heymann,et al. Mifamurtide for the treatment of nonmetastatic osteosarcoma , 2011, Expert opinion on pharmacotherapy.
[22] C. Antonescu,et al. Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations , 2010, Proceedings of the National Academy of Sciences.
[23] Marc Ladanyi,et al. Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor. , 2010, The New England journal of medicine.
[24] Helen X. Chen,et al. Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. , 2010, The New England journal of medicine.
[25] T. Nielsen,et al. EGR1 reactivation by histone deacetylase inhibitors promotes synovial sarcoma cell death through the PTEN tumor suppressor , 2010, Oncogene.
[26] Derek Y. Chiang,et al. Subtype-specific genomic alterations define new targets for soft tissue sarcoma therapy , 2010, Nature Genetics.
[27] P. Choong,et al. RANK-Fc inhibits malignancy via inhibiting ERK activation and evoking caspase-3-mediated anoikis in human osteosarcoma cells , 2010, Clinical & Experimental Metastasis.
[28] Marvin D Nelson,et al. Phase I trial of two schedules of vincristine, oral irinotecan, and temozolomide (VOIT) for children with relapsed or refractory solid tumors: A Children's Oncology Group phase I consortium study , 2010, Pediatric blood & cancer.
[29] David M. Thomas,et al. Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study. , 2010, The Lancet. Oncology.
[30] David M. Thomas,et al. Cancer‐associated neochromosomes: a novel mechanism of oncogenesis , 2009, BioEssays : news and reviews in molecular, cellular and developmental biology.
[31] D. Hwang,et al. Gastrosplenic fistula from Hodgkin's lymphoma. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[32] R. Gorlick,et al. Development of IGF-IR inhibitors in pediatric sarcomas , 2009, Current oncology reports.
[33] I. Judson,et al. Activity of cediranib, a highly potent and selective VEGF signaling inhibitor, in alveolar soft part sarcoma. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[34] L. Mirabello,et al. Osteosarcoma incidence and survival rates from 1973 to 2004 , 2009, Cancer.
[35] T. Nielsen,et al. Synergism of Heat Shock Protein 90 and Histone Deacetylase Inhibitors in Synovial Sarcoma , 2009, Sarcoma.
[36] B. Pitard,et al. Therapeutic efficacy of soluble receptor activator of nuclear factor-kappa B-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma , 2010 .
[37] F. Alt,et al. Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. , 2008, Genes & development.
[38] M. van de Rijn,et al. Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma. , 2008, Cancer research.
[39] Paul A Meyers,et al. Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[40] D. Heymann,et al. Receptor activator of nuclear factor-kappaB ligand (RANKL) directly modulates the gene expression profile of RANK-positive Saos-2 human osteosarcoma cells. , 2007, Oncology reports.
[41] B. Pitard,et al. Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption. , 2007, Cancer research.
[42] Haesun Choi,et al. Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[43] Malay Haldar,et al. A conditional mouse model of synovial sarcoma: insights into a myogenic origin. , 2007, Cancer cell.
[44] B. Le Goff,et al. Human osteosarcoma cells express functional receptor activator of nuclear factor‐kappa B , 2007, The Journal of pathology.
[45] M. Ladanyi,et al. SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma. , 2006, Cancer research.
[46] M. Capecchi,et al. New genetic tactics to model alveolar rhabdomyosarcoma in the mouse. , 2005, Cancer research.
[47] T. Nielsen,et al. Hsp90 Inhibitor 17-Allylamino-17-Demethoxygeldanamycin Prevents Synovial Sarcoma Proliferation via Apoptosis in In vitro Models , 2005, Clinical Cancer Research.
[48] Michel Martinez,et al. Most Wanted , 2005 .
[49] J. Eary,et al. FDG PET imaging guided re-evaluation of histopathologic response in a patient with high-grade sarcoma , 2003, Skeletal Radiology.
[50] M. Ladanyi,et al. Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor. , 2001, The American journal of pathology.
[51] S. Perkins,et al. ALK1 and p80 Expression and Chromosomal Rearrangements Involving 2p23 in Inflammatory Myofibroblastic Tumor , 2001, Modern Pathology.
[52] A. Albor,et al. Regulation of the human poly(ADP-ribose) polymerase promoter by the ETS transcription factor , 1999, Oncogene.
[53] K. Matthay,et al. A Phase I/IB trial of murine monoclonal anti‐GD2 antibody 14.G2a plus interleukin‐2 in children with refractory neuroblastoma , 1997, Cancer.
[54] C. Karakousis,et al. Soft tissue sarcomas in adults , 1994, CA: a cancer journal for clinicians.
[55] N. Cheung,et al. Localization of GD2-specific monoclonal antibody 3F8 in human osteosarcoma. , 1987, Cancer research.
[56] A. Jemal,et al. Cancer statistics, 2012 , 2012, CA: a cancer journal for clinicians.
[57] F. Mertens,et al. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone , 2002 .
[58] E. Kleinerman,et al. Liposome-encapsulated muramyl tripeptide: a new biologic response modifier for the treatment of osteosarcoma. , 1993, Cancer treatment and research.
[59] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.