On Neuroinformatics: Mathematical Models of Neuroscience and Neurocomputing

Neuroinformatics is a broad and rapidly evolving discipline concerned with applying information technology and computer science to solve challenges and answer pressing questions in the field of neuroscience. An emerging field of neuroinformatics attempts to model the cellular structures, properties, and functions of neural networks and their applications in neurocomputing and cognitive information systems. This paper presents a set of theories and mathematical models in neuroinformatics for neuroscience and neurocomputing. The neurological foundations of neural clusters and nervous systems are explored. A mathematical treatment of the neurological models and neural signal theories is formally described covering neural signal generation, pulse frequency modulation, and the multiplexer/demultiplexer for neural signal transmissions. Formal models of association, sensory, and motor neurons are established that explain the neurological foundation of applied artificial neural networks. Engineering applications of this neuroinformatics theory and formal neural models are elaborated in cognitive computing, neurocomputing, and neural network analyses.

[1]  Jan A. Bergstra,et al.  Real time process algebra , 1991, Formal Aspects of Computing.

[2]  David N. Kennedy,et al.  An information science infrastructure for neuroscience , 2003, Neuroinformatics.

[3]  J J Hopfield,et al.  Neural networks and physical systems with emergent collective computational abilities. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[4]  Yingxu Wang,et al.  The OAR Model of Neural Informatics for Internal Knowledge Representation in the Brain , 2007, Int. J. Cogn. Informatics Nat. Intell..

[5]  Yingxu Wang,et al.  Contemporary Cybernetics and Its Facets of Cognitive Informatics and Computational Intelligence , 2009, IEEE Transactions on Systems, Man, and Cybernetics, Part B (Cybernetics).

[6]  Viktor K. Jirsa,et al.  Connectivity and dynamics of neural information processing , 2007, Neuroinformatics.

[7]  Stephen H. Koslow,et al.  Neuroinformatics as a megascience issue , 1999, IEEE Transactions on Information Technology in Biomedicine.

[8]  Eric L. Schwartz,et al.  Computational Neuroscience , 1993, Neuromethods.

[9]  Robert A. Wilson,et al.  Book Reviews: The MIT Encyclopedia of the Cognitive Sciences , 2000, CL.

[10]  T. Woolsey,et al.  A Review for Medical Students The Brain Atlas: A Visual Guide to the Human Central Nervous System, 3rd ed. , 2009, McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students.

[11]  Michael A. Arbib,et al.  Computing the brain : a guide to neuroinformatics , 2001 .

[12]  Shusaku Tsumoto,et al.  Perspectives on eBrain and Cognitive Computing , 2012, Int. J. Cogn. Informatics Nat. Intell..

[13]  Yingxu Wang,et al.  Cognitive informatics models of the brain , 2006, IEEE Trans. Syst. Man Cybern. Syst..

[14]  Alain Destexhe,et al.  Neuronal Computations with Stochastic Network States , 2006, Science.

[15]  Yingxu Wang,et al.  On Contemporary Denotational Mathematics for Computational Intelligence , 2008, Trans. Comput. Sci..

[16]  Yingxu Wang On Cognitive Informatics , 2003 .

[17]  Edward A. Bender,et al.  Mathematical methods in artificial intelligence , 1996 .

[18]  Tim Gollisch,et al.  Modeling Single-Neuron Dynamics and Computations: A Balance of Detail and Abstraction , 2006, Science.

[19]  I. Whishaw,et al.  Fundamentals of Human Neuropsychology , 1995 .

[20]  Yingxu Wang,et al.  In Search of Denotational Mathematics: Novel Mathematical Means for Contemporary Intelligence, Brain, and Knowledge Sciences , 2012 .

[21]  Marina Chicurel,et al.  Databasing the brain , 2000, Nature.

[22]  Yingxu Wang,et al.  The Theoretical Framework of Cognitive Informatics , 2007, Int. J. Cogn. Informatics Nat. Intell..

[23]  Yingxu Wang,et al.  On Cognitive Computing , 2009, Int. J. Softw. Sci. Comput. Intell..

[24]  Yingxu Wang,et al.  On Abstract Intelligence and Brain Informatics: Mapping Cognitive Functions of the Brain onto its Neural Structures , 2012, Int. J. Cogn. Informatics Nat. Intell..

[25]  Shushma Patel,et al.  A layered reference model of the brain (LRMB) , 2006, IEEE Transactions on Systems, Man, and Cybernetics, Part C (Applications and Reviews).

[26]  Yingxu Wang,et al.  On Abstract Intelligence: Toward a Unifying Theory of Natural, Artificial, Machinable, and Computational Intelligence , 2009, Int. J. Softw. Sci. Comput. Intell..

[27]  Daniel Gardner,et al.  A gateway to the future of neuroinformatics , 2007, Neuroinformatics.

[28]  C. Frith,et al.  Mapping the Mind , 1998 .

[29]  Yingxu Wang,et al.  The Real-Time Process Algebra (RTPA) , 2002, Ann. Softw. Eng..

[30]  Bruno A. Olshausen,et al.  Book Review , 2003, Journal of Cognitive Neuroscience.

[31]  Peter Dayan,et al.  Theoretical Neuroscience: Computational and Mathematical Modeling of Neural Systems , 2001 .

[32]  Yingxu Wang,et al.  On Denotational Mathematics Foundations for the Next Generation of Computers: Cognitive Computers for Knowledge Processing , 2012 .

[33]  Yingxu Wang,et al.  Advances in Cognitive Informatics and Cognitive Computing , 2010 .