The autism symptom interview, school‐age: A brief telephone interview to identify autism spectrum disorders in 5‐to‐12‐year‐old children

This study reports on the initial validation of the Autism Symptom Interview (ASI), School‐Age, a brief (15–20 min) phone interview derived from questions from the Autism Diagnostic Interview‐Revised (ADI‐R). The ASI, School‐Age was administered by interviewers with minimal training to parents of children ages 5 to 12 who had all been previously identified with (or referred for assessment of) ASD or another neurodevelopmental disorder. Children then underwent a comprehensive assessment to determine a best‐estimate clinical diagnosis of ASD (n = 159) or non‐ASD (e.g. language disorder, intellectual disability, ADHD; n = 130). Clinicians who conducted the assessments were blind to ASI results. ROC analyses compared ASI scores to clinical diagnosis. Due to the small number of participants with non‐ASD diagnoses who were classified as nonverbal (i.e. not yet using phrases on a daily basis), it was not possible to assess sensitivity and specificity of the nonverbal algorithm in this sample. The verbal algorithm yielded a sensitivity of 0.87 (95% CI = 0.81–0.92) and a specificity of 0.62 (95% CI = 0.53–0.70). When used in conjunction with the Autism Diagnostic Observation Schedule (ADOS), sensitivity and specificity were 0.82 (95% CI = 0.74–0.88) and 0.92 (95% CI = 0.86–0.96), respectively. Internal consistency and test‐retest reliability were both excellent. Particularly for verbal school age children, the ASI may serve as a useful tool to more quickly ascertain or classify children with ASD for research or clinical triaging purposes. Additional data collection is underway to determine the utility of the ASI in children who are younger and/or nonverbal. Autism Res 2017, 10: 78–88. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.

[1]  C. Corsello,et al.  How interview questions are placed in time influences caregiver description of social communication symptoms on the ADI-R. , 2015, Journal of child psychology and psychiatry, and allied disciplines.

[2]  S. Bölte,et al.  The added value of the combined use of the Autism Diagnostic Interview–Revised and the Autism Diagnostic Observation Schedule: Diagnostic validity in a clinical Swedish sample of toddlers and young preschoolers , 2015, Autism : the international journal of research and practice.

[3]  C. Lord,et al.  Predicting young adult outcome among more and less cognitively able individuals with autism spectrum disorders. , 2014, Journal of child psychology and psychiatry, and allied disciplines.

[4]  Ron Dumont,et al.  Differential Ability Scales–Second Edition , 2014 .

[5]  Yoko Kamio,et al.  Reliability and Validity of Autism Diagnostic Interview-Revised, Japanese Version , 2013, Journal of autism and developmental disorders.

[6]  Tony Charman,et al.  Measurement Issues: Screening and diagnostic instruments for autism spectrum disorders - lessons from research and practice. , 2013, Child and adolescent mental health.

[7]  Somer Bishop,et al.  Factors influencing scores on the social responsiveness scale. , 2013, Journal of child psychology and psychiatry, and allied disciplines.

[8]  Letitia R. Naigles,et al.  Optimal outcome in individuals with a history of autism , 2013, BDJ.

[9]  Catherine Lord,et al.  Annual research review: re-thinking the classification of autism spectrum disorders. , 2012, Journal of child psychology and psychiatry, and allied disciplines.

[10]  K. Toth,et al.  Diagnosis of autism spectrum disorders. , 2011, Pediatric annals.

[11]  Vanessa Hus,et al.  Telescoping of caregiver report on the Autism Diagnostic Interview--Revised. , 2011, Journal of child psychology and psychiatry, and allied disciplines.

[12]  C. Lord,et al.  Diagnosis of Autism Spectrum Disorders , 2011 .

[13]  C. Molloy,et al.  Use of the Autism Diagnostic Observation Schedule (ADOS) in a clinical setting , 2011, Autism : the international journal of research and practice.

[14]  C. Lord,et al.  The Simons Simplex Collection: A Resource for Identification of Autism Genetic Risk Factors , 2010, Neuron.

[15]  I. Cohen,et al.  Brief Report: Telephone Administration of the Autism Diagnostic Interview—Revised: Reliability and Suitability for Use in Research , 2010, Journal of autism and developmental disorders.

[16]  Ingrid Obsuth,et al.  Child Behavior Checklist , 2010 .

[17]  C. Drew Vineland Adaptive Behavior Scales , 2010 .

[18]  Vanessa Hus,et al.  The Autism Diagnostic Observation Schedule—Toddler Module: A New Module of a Standardized Diagnostic Measure for Autism Spectrum Disorders , 2009, Journal of autism and developmental disorders.

[19]  B. Tonge,et al.  Using the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule with Young Children with Developmental Delay: Evaluating Diagnostic Validity , 2008, Journal of autism and developmental disorders.

[20]  C. Lord,et al.  Re-examining the core features of autism: a comparison of autism spectrum disorder and fetal alcohol spectrum disorder. , 2007, Journal of child psychology and psychiatry, and allied disciplines.

[21]  G. Baird,et al.  Validation of the social communication questionnaire in a population cohort of children with autism spectrum disorders. , 2007, Journal of the American Academy of Child and Adolescent Psychiatry.

[22]  Carrie Dunn Can you kick it , 2007 .

[23]  C. Lord,et al.  The Autism Diagnostic Observation Schedule: Revised Algorithms for Improved Diagnostic Validity , 2007, Journal of autism and developmental disorders.

[24]  P. Herzberg,et al.  Diagnostic instruments , 2006, Psycho-social medicine.

[25]  C. Corsello,et al.  Combining information from multiple sources in the diagnosis of autism spectrum disorders. , 2006, Journal of the American Academy of Child and Adolescent Psychiatry.

[26]  J. Pandey,et al.  Agreement Among Four Diagnostic Instruments for Autism Spectrum Disorders in Toddlers , 2006, Journal of autism and developmental disorders.

[27]  E. Leibenluft,et al.  Autism spectrum traits in children with mood and anxiety disorders. , 2005, Journal of child and adolescent psychopharmacology.

[28]  Rhea Paul,et al.  Language and communication in autism , 2005 .

[29]  Maurice Place,et al.  The developmental, dimensional and diagnostic interview (3di): a novel computerized assessment for autism spectrum disorders. , 2004, Journal of the American Academy of Child and Adolescent Psychiatry.

[30]  S. Spence,et al.  A genomewide screen of 345 families for autism-susceptibility loci. , 2003, American journal of human genetics.

[31]  S. Leekam,et al.  The Diagnostic Interview for Social and Communication Disorders: background, inter-rater reliability and clinical use. , 2002, Journal of child psychology and psychiatry, and allied disciplines.

[32]  B. Leventhal,et al.  The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism , 2000, Journal of autism and developmental disorders.

[33]  James D. A. Parker,et al.  The Revised Conners' Parent Rating Scale (CPRS-R): Factor Structure, Reliability, and Criterion Validity , 1998, Journal of abnormal child psychology.

[34]  S. Spence,et al.  A measure of anxiety symptoms among children. , 1998, Behaviour research and therapy.

[35]  C. Gillberg,et al.  The long‐term course of autistic disorders: update on follow‐up studies , 1998, Acta psychiatrica Scandinavica.

[36]  S. Bradley-Johnson Mullen Scales of Early Learning , 1997 .

[37]  J. Parker,et al.  The Multidimensional Anxiety Scale for Children (MASC): factor structure, reliability, and validity. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[38]  A Pickles,et al.  Language level and nonverbal social-communicative behaviors in autistic and language-delayed children. , 1996, Journal of the American Academy of Child and Adolescent Psychiatry.

[39]  A. Couteur,et al.  Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders , 1994, Journal of autism and developmental disorders.

[40]  C. Lord,et al.  Using the ADI-R to diagnose autism in preschool children , 1993 .

[41]  G Kishi,et al.  Reliability and Validity , 1999 .

[42]  Kathleen M Houston,et al.  The interview questions , 2016 .

[43]  K. Fountoulakis Long-Term Course , 2015 .

[44]  A. John Bailer,et al.  Combining information , 2009, Wiley interdisciplinary reviews. Computational statistics.

[45]  C. Lord,et al.  Restricted and Repetitive Behaviors in Young Children with Autism Spectrum Disorders , 2007, Journal of autism and developmental disorders.

[46]  Susan Risi,et al.  Frameworks and methods in diagnosing autism spectrum disorders , 1998 .

[47]  G. Garrido Cantarero,et al.  [The area under the ROC curve]. , 1996, Medicina clinica.

[48]  D. Cicchetti Guidelines, Criteria, and Rules of Thumb for Evaluating Normed and Standardized Assessment Instruments in Psychology. , 1994 .