N-Mannich-Base Prodrugs of 5-Iodo-2′-deoxycytidine as Topical Delivery Enhancers

[1]  K. Sloan,et al.  N-Mannich base derivatives of 5-fluorocytosine: A prodrug approach to improve topical delivery , 1987 .

[2]  F. Flowers,et al.  Use of solubility parameters of drug and vehicle to predict flux through skin. , 1986, The Journal of investigative dermatology.

[3]  K. Sloan,et al.  Mannich base derivatives of theophylline and 5-fluorouracil: syntheses, properties and topical delivery characteristics , 1984 .

[4]  K. Sloan,et al.  The aminomethylation of adenine, cytosine and guanine , 1984 .

[5]  R. L. Elder.  The cosmetic ingredient review--a safety evaluation program. , 1984, Journal of the American Academy of Dermatology.

[6]  R. T. Walker,et al.  Comparative efficacy of antiherpes drugs against different strains of herpes simplex virus. , 1980, The Journal of infectious diseases.

[7]  H. Bundgaard,et al.  Prodrugs as drug delivery systems IV: N-Mannich bases as potential novel prodrugs for amides, ureides, amines, and other NH-acidic compounds. , 1980, Journal of pharmaceutical sciences.

[8]  P. V. von Hippel,et al.  Formaldehyde as a probe of DNA structure. I. Reaction with exocyclic amino groups of DNA bases. , 1975, Biochemistry.

[9]  G. Cooper,et al.  Selective inhibition of the replication of herpes simplex virus by 5-halogenated analogues of deoxycytidine. , 1975, Molecular pharmacology.

[10]  N. Bodor,et al.  Rational development of a soluble prodrug of a cytotoxic nucleoside: preparation and properties of arabinosyladenine 5'-formate. , 1975, Journal of pharmaceutical sciences.

[11]  L. Sun,et al.  Reaction of cytidine with ethylating agents. , 1974, Biochemistry.

[12]  W. Jencks.  Catalysis in chemistry and enzymology , 1969 .

[13]  W. Creasey.  Studies on the metabolism of 5-iodo-2'-deoxycytidine in vitro. Purification of nucleoside deaminase from mouse kidney. , 1963, The Journal of biological chemistry.