A systematic review of methodologies, endpoints, and outcome measures in randomized trials of radiation therapy-induced nausea and vomiting

[1]  M. Kris,et al.  Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[2]  A. Feizi,et al.  The efficacy of combination of ondansetron and aprepitant on preventing the radiotherapy-induced nausea and vomiting , 2015, Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences.

[3]  C. Wong,et al.  Timing and duration of 5-HT3 receptor antagonist therapy for the prophylaxis of radiotherapy-induced nausea and vomiting: a systematic review of randomized and non-randomized studies , 2013, Journal of Radiation Oncology.

[4]  Liying Zhang,et al.  International patterns of practice in the management of radiation therapy-induced nausea and vomiting. , 2012, International journal of radiation oncology, biology, physics.

[5]  G. Steineck,et al.  Acupuncture compared with placebo acupuncture in radiotherapy-induced nausea--a randomized controlled study. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.

[6]  B. Sorbe,et al.  Tropisetron, a New 5-HT3-Receptor Antagonist, in the Prevention of Radiation-Induced Nausea, Vomiting and Diarrhoea , 2012, Drugs.

[7]  E. Maranzano,et al.  Radiotherapy-induced nausea and vomiting , 2011, Expert review of pharmacoeconomics & outcomes research.

[8]  M. Ingvar,et al.  Getting the Grip on Nonspecific Treatment Effects: Emesis in Patients Randomized to Acupuncture or Sham Compared to Patients Receiving Standard Care , 2011, PloS one.

[9]  A. Molassiotis,et al.  Radiotherapy-induced nausea and vomiting (RINV): MASCC/ESMO guideline for antiemetics in radiotherapy: update 2009 , 2011, Supportive Care in Cancer.

[10]  A. Molassiotis,et al.  Antiemetic research: future directions , 2011, Supportive Care in Cancer.

[11]  Guang-hui Li,et al.  Berberine inhibits acute radiation intestinal syndrome in human with abdomen radiotherapy , 2010, Medical oncology.

[12]  S. Keats.  High-dose rate brachytherapy in prostate cancer patients--a study on nausea and vomiting. , 2010, Urologic nursing.

[13]  R. Orecchia,et al.  A prospective observational trial on emesis in radiotherapy: analysis of 1020 patients recruited in 45 Italian radiation oncology centres. , 2010, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[14]  V. Kouloulias,et al.  A comparative study of prophylactic antiemetic treatment in cancer patients receiving radiotherapy. , 2010, Journal of B.U.ON. : official journal of the Balkan Union of Oncology.

[15]  J. Cui,et al.  Hydrogen therapy may be an effective and specific novel treatment for acute radiation syndrome. , 2010, Medical hypotheses.

[16]  P. Jean-Pierre,et al.  Acupressure bands are effective in reducing radiation therapy-related nausea. , 2009, Journal of pain and symptom management.

[17]  M. Pinkowish.  Acupressure and Acupuncture for Side Effects of Radiotherapy , 2009, CA: a cancer journal for clinicians.

[18]  D. Moher,et al.  Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement , 2009, BMJ.

[19]  Jin‐Young Jang,et al.  Ramosetron for the prevention of nausea and vomiting during 5-fluorouracil-based chemoradiotherapy for pancreatico-biliary cancer. , 2008, Japanese journal of clinical oncology.

[20]  P. Loehrer.  5-Hydroxytryptamine-3 Receptor Antagonist With or Without Short-Course Dexamethasone in the Prophylaxis of Radiation Induced Emesis: A Placebo-Controlled Randomized Trial of the National Cancer Institute of Canada Clinical Trials Group (SC19) , 2007 .

[21]  S. Bourdin,et al.  A double-blind, placebo-controlled trial of i.v. dolasetron mesilate in the prevention of radiotherapy-induced nausea and vomiting in cancer patients , 1996, Supportive Care in Cancer.

[22]  A. Favero,et al.  Methodology of trials with antiemetics , 1996, Supportive Care in Cancer.

[23]  K. Bremer.  5-Hydroxytryptamine (serotonin) subtype 3 antagonists, a major step in prophylaxis and control of cytostatic and radiation-induced emesis , 2005, Journal of Cancer Research and Clinical Oncology.

[24]  M. Aapro.  Methodological issues in antiemetic studies , 1993, Investigational New Drugs.

[25]  A. Favero,et al.  Assessment of nausea , 2004, European Journal of Clinical Pharmacology.

[26]  P. Wischmeyer,et al.  Prevention of chemotherapy and radiation toxicity with glutamine. , 2003, Cancer treatment reviews.

[27]  A. Bezjak,et al.  Primary treatment endpoint following palliative radiotherapy for painful bone metastases: need for a consensus definition? , 2002, Clinical oncology (Royal College of Radiologists (Great Britain)).

[28]  D. M. Sherman,et al.  The Efficacy and Safety of Once-Daily Kytril® (Granisetron Hydrochloride) Tablets in the Prophylaxis of Nausea and Emesis Following Fractionated Upper Abdominal Radiotherapy , 2001, Cancer investigation.

[29]  M. Morita,et al.  Antiemetic effect of ramosetron during hyperthermo-chemo-radiotherapy for esophageal cancer. , 2000, Anticancer research.

[30]  J. Raschko,et al.  Double-blind, randomized, parallel-group study on the efficacy and safety of oral granisetron and oral ondansetron in the prophylaxis of nausea and vomiting in patients receiving hyperfractionated total body irradiation , 2000, Bone Marrow Transplantation.

[31]  A. Bezjak,et al.  Dexamethasone for the prophylaxis of radiation-induced emesis: a National Cancer Institute of Canada Clinical Trials Group phase III study. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[32]  L. Goedhals,et al.  Efficacy of an ondansetron orally disintegrating tablet: a novel oral formulation of this 5-HT(3) receptor antagonist in the treatment of fractionated radiotherapy-induced nausea and emesis. Emesis Study Group for the Ondansetron Orally Disintegrating Tablet in Radiotherapy Treatment. , 1999, Clinical oncology (Royal College of Radiologists (Great Britain)).

[33]  A. Favero,et al.  Radiation-induced emesis: a prospective observational multicenter Italian trial. The Italian Group for Antiemetic Research in Radiotherapy. , 1999, International journal of radiation oncology, biology, physics.

[34]  J. Neumann,et al.  Antiemetic efficacy of granisetron plus dexamethasone in bone marrow transplant patients receiving chemotherapy and total body irradiation , 1999, Bone Marrow Transplantation.

[35]  S. Pergolizzi,et al.  Escalating dose of oral ondansetron in the prevention of radiation induced emesis. , 1998, Anticancer research.

[36]  M. Tonato,et al.  Methodology of antiemetic trials: response assessment, evaluation of new agents and definition of chemotherapy emetogenicity , 1998, Supportive Care in Cancer.

[37]  M. K. Mahajan,et al.  Assessment of efficacy of pyridoxine in control of radiation induced sickness. , 1998, Journal of the Indian Medical Association.

[38]  S. Fosså,et al.  Prophylactic use of tropisetron or metoclopramide during adjuvant abdominal radiotherapy of seminoma stage I: a randomised, open trial in 23 patients. , 1997, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[39]  A. Kiltie,et al.  Ondansetron versus a chlorpromazine and dexamethasone combination for the prevention of nausea and vomiting: a prospective, randomised study to assess efficacy, cost effectiveness and quality of life following single-fraction radiotherapy , 1997, Supportive Care in Cancer.

[40]  D. Dearnaley,et al.  The effect of antiemetics and reduced radiation fields on acute gastrointestinal morbidity of adjuvant radiotherapy in stage I seminoma of the testis: a randomized pilot study. , 1997, Clinical oncology (Royal College of Radiologists (Great Britain)).

[41]  R. Henriksson,et al.  A randomised placebo controlled study with ondansetron in patients undergoing fractionated radiotherapy. , 1996, Annals of oncology : official journal of the European Society for Medical Oncology.

[42]  E. Touboul,et al.  Total body irradiation prior to bone marrow transplantation: efficacy and safety of granisetron in the prophylaxis and control of radiation-induced emesis. , 1996, International journal of radiation oncology, biology, physics.

[43]  I. Olver,et al.  Antiemetic study methodology: recommendations for future studies. , 1996, Oncology.

[44]  S. Asano,et al.  Granisetron in the prevention of vomiting induced by conditioning for stem cell transplantation: a prospective randomized study. , 1996, Bone marrow transplantation.

[45]  S. J. Gibbs,et al.  A pilot study to evaluate the cost-effectiveness of ondansetron and granisetron in fractionated total body irradiation. , 1996, Clinical oncology (Royal College of Radiologists (Great Britain)).

[46]  A. Rosset,et al.  Nausea and vomiting in fractionated radiotherapy: a prospective on-demand trial of tropisetron rescue for non-responders to metoclopramide. , 1995, European journal of cancer.

[47]  H. Prentice,et al.  Granisetron in the prevention of irradiation-induced emesis. , 1995, Bone marrow transplantation.

[48]  E. Cirenza,et al.  Randomized double-blind, placebo-controlled evaluation of oral ondansetron in the prevention of nausea and vomiting associated with fractionated total-body irradiation. , 1994, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[49]  H. Kooy,et al.  The prevention of radiosurgery-induced nausea and vomiting by ondansetron: evidence of a direct effect on the central nervous system chemoreceptor trigger zone. , 1994, Surgical neurology.

[50]  L. G. Hoffman,et al.  On the mechanism of radiation-induced emesis: the role of serotonin. , 1994, International journal of radiation oncology, biology, physics.

[51]  M. Clavel,et al.  Improved control of emesis and quality of life with ondansetron in breast cancer. , 1993, Oncology.

[52]  T. Priestman,et al.  A prospective randomized double-blind trial comparing ondansetron versus prochlorperazine for the prevention of nausea and vomiting in patients undergoing fractionated radiotherapy. , 1993, Clinical oncology (Royal College of Radiologists (Great Britain)).

[53]  C. Marquez,et al.  Ondansetron for patients given abdominal radiotherapy , 1992, The Lancet.

[54]  B. Sorbe,et al.  Tropisetron, a new 5-HT3 receptor antagonist, in the prevention of radiation-induced emesis. , 1992, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[55]  D. Tait,et al.  Results of a double blind placebo controlled study of ondansetron as an antiemetic during total body irradiation in patients undergoing bone marrow transplantation. , 1992, Leukemia & lymphoma.

[56]  R. Henriksson,et al.  The effect of ondansetron on radiation-induced emesis and diarrhoea. , 1992, Acta oncologica.

[57]  J. Roberts.  Ondansetron in the control of refractory emesis following radiotherapy. , 1992, Clinical oncology (Royal College of Radiologists (Great Britain)).

[58]  B. Sorbe,et al.  Tropisetron, a new 5-HT3 receptor antagonist, in the prevention of irradiation-induced nausea, vomiting and diarrhoea. , 1992, European journal of gynaecological oncology.

[59]  J. Logue,et al.  The antiemetic effect of granisetron in lower hemibody radiotherapy. , 1991, Clinical oncology (Royal College of Radiologists (Great Britain)).

[60]  T. Priestman,et al.  The final assessment of a randomized double-blind comparative study of ondansetron vs. metoclopramide in the prevention of nausea and vomiting following high-dose upper abdominal irradiation. , 1991, Clinical oncology (Royal College of Radiologists (Great Britain)).

[61]  T. Priestman,et al.  Results of a randomized, double-blind comparative study of ondansetron and metoclopramide in the prevention of nausea and vomiting following high-dose upper abdominal irradiation. , 1990, Clinical oncology (Royal College of Radiologists (Great Britain)).

[62]  P. Canney,et al.  A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea. , 1987, Clinical radiology.

[63]  G. Sanger,et al.  Evidence that 5-hydroxytryptamine3 receptors mediate cytotoxic drug and radiation-evoked emesis. , 1987, British Journal of Cancer.

[64]  R. Simon,et al.  Antiemetic studies: a methodological discussion. , 1986, Cancer treatment reports.

[65]  G. Morrow.  Methodology in behavioral and psychosocial cancer research. The assessment of nausea and vomiting. Past problems, current issues and suggestions for future research. , 1984, Cancer.

[66]  L. Fairbanks,et al.  Tetrahydrocannabinol vs. prochlorperazine. The effects of two antiemetics on patients undergoing radiotherapy. , 1984, Radiology.

[67]  M. Palmer,et al.  Randomised clinical trial of levonantradol and chlorpromazine in the prevention of radiotherapy-induced vomiting. , 1982, Clinical radiology.

[68]  S. Frytak,et al.  Management of nausea and vomiting in the cancer patient. , 1981, JAMA.

[69]  D. Welch.  Assessment of nausea and vomiting in cancer patients undergoing external beam radiotherapy , 1980, Cancer nursing.

[70]  R. Mortel,et al.  Prophylactic ibuprofen administration during pelvic irradiation. , 1979, International journal of radiation oncology, biology, physics.

[71]  G. Rowlands,et al.  A Trial of Valoid (cyclizine) Tablets in the Control of the Nausea and Vomiting Associated with Radiation Therapy , 1976, The British journal of clinical practice.

[72]  H. J. Collier,et al.  TREATMENT OF RADIATION-INDUCED GASTROINTESTINAL DISTRESS WITH ACETYLSALICYLATE , 1975, The Lancet.

[73]  D. R. Cole,et al.  Haloperidol for radiation sickness: Control of associated nausea, vomiting, and anorexia. , 1974, New York state journal of medicine.

[74]  F. Tornetta.  Double‐Blind Evaluation of Haloperidol for Antiemetic Activity , 1972, Anesthesia and analgesia.

[75]  W. Duncan,et al.  The prevention of radiation sickness. Report of a double blind random clinical trial using prochlorperazine and metopimazine. , 1971, Clinical radiology.

[76]  F. Chu,et al.  A controlled clinical study of metopimazine and perphenazine in treatment of radiation nausea and vomiting , 1969, Clinical pharmacology and therapeutics.

[77]  T. Backhouse,et al.  An assessment of thiethylperazine (Torecan) in the control of radiation-induced nausea and vomiting. , 1968, Clinical radiology.

[78]  E. W. Emery,et al.  Treatment of radiation sickness with pyridoxine hydrochloride in outpatients of a radiotherapy unit. , 1967, British medical journal.

[79]  P. Rubin,et al.  Factor concerned with "clinical radiation nausea". , 1966, Radiology.

[80]  J. Holt.  A trial of thiethylperazine ("Torecan") in patients suffering from radiation sickness. , 1965, The Medical journal of Australia.

[81]  Johnson Em.  The control of radiation sickness with thiethylperazine (torecan). , 1965 .

[82]  E. M. Johnson.  The control of radiation sickness with thiethylperazine (torecan). , 1965, The New Zealand medical journal.

[83]  K. Fochem.  [ON THE TREATMENT OF RADIATION SYNDROMES WITH CYCLIZINE (MAREZINE)]. , 1964, Therapeutische Umschau. Revue therapeutique.

[84]  J. Donovan.  Radiation sickness and its control with thiethylperazine ("Torecan"): a preliminary evaluation. , 1963, The Medical journal of Australia.

[85]  W. Jasiński,et al.  [Treatment of radiation sickness with Marzine (cyclizine HCl)]. , 1962, Polski przeglad radiologii i medycyny nuklearnej.

[86]  J. Cox,et al.  Nausea and vomiting: control by thiethylperazine. , 1962, Current therapeutic research, clinical and experimental.

[87]  F. Foldes,et al.  The use of trimethobenzamide (tigan) for the treatment of radiation induced nausea and emesis. , 1961, The American journal of roentgenology, radium therapy, and nuclear medicine.

[88]  J. Webster,et al.  Evaluation of the Placebo Effect in the Treatment of Radiation Sickness , 1961 .

[89]  R. Finney.  ''Nidoxital'': a clinical trial. , 1961, Clinical radiology.

[90]  Codiga Va.  A new antiemetic for the treatment of nausea and vomiting associated with roentgen therapy. , 1961 .

[91]  V. A. Codiga.  A new antiemetic for the treatment of nausea and vomiting associated with roentgen therapy. , 1961, International record of medicine.

[92]  I. Kuzma,et al.  The application of the antikinetic therapeutic agent "marzine" in the treatment of the radiation sickness. , 1960, Neoplasma.

[93]  M. Solan.  Prochlorperazine and Irradiation Sickness , 1959, British medical journal.

[94]  R. Finney.  Cortisone and the treatment of radiation sickness. , 1958, The Journal of the Faculty of Radiologists. Faculty of Radiologists.

[95]  B. Stoll.  New drugs for irradiation sickness. , 1957, Radiology.

[96]  M. Kligerman,et al.  A study of the effectiveness of pyridoxine and dramamine on clinical radiation sickness. , 1956, Radiology.

[97]  W. Brown.  Symptomatic Disturbance after Single Therapeutic Dose of X Rays , 1953, British medical journal.

[98]  B. Stoll,et al.  Radiation sickness; a clinical investigation. , 1952, The Journal of the Faculty of Radiologists. Faculty of Radiologists.