Premarin improves memory, prevents scopolamine-induced amnesia and increases number of basal forebrain choline acetyltransferase positive cells in middle-aged surgically menopausal rats

[1]  David A. Johnson,et al.  Selective lesion of septal cholinergic neurons in rats impairs acquisition of a delayed matching to position T-maze task by delaying the shift from a response to a place strategy , 2008, Brain Research Bulletin.

[2]  J. Bohacek,et al.  Long‐Term Ovarian Hormone Deprivation Alters the Ability of Subsequent Oestradiol Replacement to Regulate Choline Acetyltransferase Protein Levels in the Hippocampus and Prefrontal Cortex of Middle‐Aged Rats , 2008, Journal of neuroendocrinology.

[3]  S. West,et al.  Higher levels of estradiol replacement correlate with better spatial memory in surgically menopausal young and middle-aged rats , 2008, Neurobiology of Learning and Memory.

[4]  A. Walf,et al.  Conjugated equine estrogen enhances rats' cognitive, anxiety, and social behavior , 2008, Neuroreport.

[5]  B. Sherwin,et al.  Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: A critical review , 2008, Frontiers in Neuroendocrinology.

[6]  H. Scharfman,et al.  Changes in hippocampal function of ovariectomized rats after sequential low doses of estradiol to simulate the preovulatory estrogen surge , 2007, The European journal of neuroscience.

[7]  M. Kawata,et al.  Effects of estrogens on cholinergic neurons in the rat basal nucleus , 2007, The Journal of Steroid Biochemistry and Molecular Biology.

[8]  Zuzana Hruska,et al.  The effects of chronic estradiol treatment on working memory deficits induced by combined infusion of β-amyloid (1–42) and ibotenic acid , 2007, Hormones and Behavior.

[9]  R. Gibbs Estradiol enhances DMP acquisition via a mechanism not mediated by turning strategy but which requires intact basal forebrain cholinergic projections , 2007, Hormones and Behavior.

[10]  David A. Johnson,et al.  Cholinergic lesions produce task-selective effects on delayed matching to position and configural association learning related to response pattern and strategy , 2007, Neurobiology of Learning and Memory.

[11]  R. Cooper,et al.  The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies. , 2007, Birth defects research. Part B, Developmental and reproductive toxicology.

[12]  K. Francis,et al.  Progesterone reverses the spatial memory enhancements initiated by tonic and cyclic oestrogen therapy in middle‐aged ovariectomized female rats , 2006, The European journal of neuroscience.

[13]  S. Resnick,et al.  0021-972X/06/$15.00/0 The Journal of Clinical Endocrinology & Metabolism 91(5):1802–1810 Printed in U.S.A. Copyright © 2006 by The Endocrine Society doi: 10.1210/jc.2005-2097 Effects of Combination Estrogen Plus Progestin Hormone Treatment on Cognition an , 2022 .

[14]  B. Sherwin Estrogen and cognitive aging in women , 2006, Neuroscience.

[15]  Paul Newhouse,et al.  Estrogen Treatment Effects on Anticholinergic-Induced Cognitive Dysfunction in Normal Postmenopausal Women , 2006, Neuropsychopharmacology.

[16]  J. Daniel,et al.  Role of hippocampal M2 muscarinic receptors in the estrogen-induced enhancement of working memory , 2005, Neuroscience.

[17]  M. Stefanick Estrogens and progestins: background and history, trends in use, and guidelines and regimens approved by the US Food and Drug Administration. , 2005, The American journal of medicine.

[18]  J. P. Morgan,et al.  Design and Analysis: A Researcher's Handbook , 2005, Technometrics.

[19]  Paul E. Gold,et al.  Acetylcholine release in hippocampus and striatum during testing on a rewarded spontaneous alternation task , 2005, Neurobiology of Learning and Memory.

[20]  H Kuhl,et al.  Pharmacology of estrogens and progestogens: influence of different routes of administration , 2005, Climacteric : the journal of the International Menopause Society.

[21]  Sterling C. Johnson,et al.  Clinical Pharmacology and Differential Cognitive Efficacy of Estrogen Preparations , 2005, Annals of the New York Academy of Sciences.

[22]  B. Winblad,et al.  Effects of estrogen and progesterone treatment on rat hippocampal NMDA receptors: Relationship to Morris water maze performance , 2004, Journal of cellular and molecular medicine.

[23]  Yong Cheng,et al.  Long‐term effects of melatonin or 17β‐estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats , 2004, Journal of pineal research.

[24]  L. Thal,et al.  Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study , 2004, JAMA.

[25]  JoAnn E Manson,et al.  Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study. , 2004, JAMA.

[26]  J. Morrison,et al.  Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys , 2004, The Journal of comparative neurology.

[27]  Ravinder J. Singh,et al.  Liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of estradiol and estrone in human plasma. , 2004, Clinical chemistry.

[28]  L. K. Marriott,et al.  Short-term estrogen treatment in ovariectomized rats augments hippocampal acetylcholine release during place learning , 2003, Neurobiology of Learning and Memory.

[29]  T. Foster,et al.  Interaction of age and chronic estradiol replacement on memory and markers of brain aging , 2003, Neurobiology of Aging.

[30]  A. Savonenko,et al.  The cognitive effects of ovariectomy and estrogen replacement are modulated by aging , 2003, Neuroscience.

[31]  V. Luine,et al.  Rapid enhancement of visual and place memory by estrogens in rats. , 2003, Endocrinology.

[32]  B. Bhavnani Estrogens and menopause: pharmacology of conjugated equine estrogens and their potential role in the prevention of neurodegenerative diseases such as Alzheimer’s , 2003, The Journal of Steroid Biochemistry and Molecular Biology.

[33]  Robert B Wallace,et al.  Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women's Health Initiative Memory Study: a randomized controlled trial. , 2003, JAMA.

[34]  Paul E. Gold,et al.  Patterns of brain acetylcholine release predict individual differences in preferred learning strategies in rats , 2003, Neurobiology of Learning and Memory.

[35]  A. Granholm,et al.  Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome , 2002, Physiology & Behavior.

[36]  R. Gibbs Basal Forebrain Cholinergic Neurons Are Necessary for Estrogen to Enhance Acquisition of a Delayed Matching-to-Position T-Maze Task , 2002, Hormones and Behavior.

[37]  J. Juraska,et al.  Ovarian Hormone Replacement to Aged Ovariectomized Female Rats Benefits Acquisition of the Morris Water Maze , 2002, Hormones and Behavior.

[38]  M. Anthony,et al.  Effects of long-term hormone replacement and of tibolone on choline acetyltransferase and acetylcholinesterase activities in the brains of ovariectomized, cynomologous monkeys , 2002, Neuroscience.

[39]  V. Denenberg,et al.  Differential learning strategies in spatial and nonspatial versions of the Morris water maze in the C57BL/6J inbred mouse strain , 2002, Behavioural Brain Research.

[40]  V. Denenberg,et al.  Spatial and nonspatial Morris maze learning: impaired behavioral flexibility in mice with ectopias located in the prefrontal cortex , 2002, Behavioural Brain Research.

[41]  C. Schneeberger,et al.  Production and actions of estrogens. , 2002, The New England journal of medicine.

[42]  R. Brinton,et al.  The women’s health initiative estrogen replacement therapy is neurotrophic and neuroprotective , 2000, Neurobiology of Aging.

[43]  R. Brinton,et al.  The estrogen replacement therapy of the Women's Health Initiative promotes the cellular mechanisms of memory and neuronal survival in neurons vulnerable to Alzheimer's disease. , 2000, Maturitas.

[44]  R. Gibbs Long-term treatment with estrogen and progesterone enhances acquisition of a spatial memory task by ovariectomized aged rats☆ , 2000, Neurobiology of Aging.

[45]  G. Dohanich,et al.  Estrogen Improves Working But Not Reference Memory and Prevents Amnestic Effects of Scopolamine on a Radial-Arm Maze , 1999, Pharmacology Biochemistry and Behavior.

[46]  V. Denenberg,et al.  Estradiol facilitates performance as working memory load increases , 1999, Psychoneuroendocrinology.

[47]  M A Espeland,et al.  The Women's Health Initiative Memory Study (WHIMS): a trial of the effect of estrogen therapy in preventing and slowing the progression of dementia. , 1998, Controlled clinical trials.

[48]  David A. Johnson,et al.  Estrogen Replacement Attenuates Effects of Scopolamine and Lorazepam on Memory Acquisition and Retention , 1998, Hormones and Behavior.

[49]  G. Dohanich,et al.  Estrogen Improves Performance of Reinforced T-Maze Alternation and Prevents the Amnestic Effects of Scopolamine Administered Systemically or Intrahippocampally , 1998, Neurobiology of Learning and Memory.

[50]  D. Dorsa,et al.  Effects of estrogen replacement on choline acetyltransferase and trkA mRNA expression in the basal forebrain of aged rats , 1998, Brain Research.

[51]  G. Dohanich,et al.  Estrogen Enhances Performance of Female Rats during Acquisition of a Radial Arm Maze , 1997, Hormones and Behavior.

[52]  M. Packard,et al.  Posttraining Estradiol Injections Enhance Memory in Ovariectomized Rats: Cholinergic Blockade and Synergism , 1997, Neurobiology of Learning and Memory.

[53]  J. Ashby,et al.  Activity of raloxifene in immature and ovariectomized rat uterotrophic assays. , 1997, Regulatory toxicology and pharmacology : RTP.

[54]  R. Gibbs Effects of estrogen on basal forebrain cholinergic neurons vary as a function of dose and duration of treatment , 1997, Brain Research.

[55]  C. Singer,et al.  The effects of ovariectomy and estrogen replacement on trkA and choline acetyltransferase mRNA expression in the basal forebrain of the adult female Sprague-Dawley rat , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[56]  RB Gibbs,et al.  Fluctuations in relative levels of choline acetyltransferase mRNA in different regions of the rat basal forebrain across the estrous cycle: effects of estrogen and progesterone , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[57]  M. O’Connell Pharmacokinetic and Pharmacologic Variation Between Different Estrogen Products , 1995, Journal of clinical pharmacology.

[58]  D. Olton,et al.  Age-related spatial reference and working memory deficits assessed in the water maze , 1995, Neurobiology of Aging.

[59]  N. Hagino,et al.  Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports. , 1995, Dementia.

[60]  V. Luine,et al.  Effects of estradiol on radial arm maze performance of young and aged rats. , 1994, Behavioral and neural biology.

[61]  G. Dohanich,et al.  Estrogen and estrogen-progesterone treatments counteract the effect of scopolamine on reinforced T-maze alternation in female rats. , 1994, Behavioral neuroscience.

[62]  D. Pfaff,et al.  Effects of Estrogen Replacement on the Relative Levels of Choline Acetyltransferase, trkA, and Nerve Growth Factor Messenger RNAs in the Basal Forebrain and Hippocampal Formation of Adult Rats , 1994, Experimental Neurology.

[63]  W. Millard,et al.  Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats , 1994, Brain Research.

[64]  A. Galaburda,et al.  Lashley maze learning deficits in NZB mice , 1992, Physiology & Behavior.

[65]  D. Pfaff,et al.  Effects of estrogen and fimbria/fornix transection on p75NGFR and ChAT expression in the medial septum and diagonal band of Broca , 1992, Experimental Neurology.

[66]  S B Dunnett,et al.  Proactive interference effects on short-term memory in rats: I. Basic parameters and drug effects. , 1990, Behavioral neuroscience.

[67]  S. Iversen,et al.  Proactive interference effects on short-term memory in rats: II. Effects in young and aged rats. , 1990, Behavioral neuroscience.

[68]  W. V. Thayne,et al.  Age-related alterations in follicular development and hormonal profiles in rats with 4-day estrous cycles. , 1990, Biology of reproduction.

[69]  G. Winocur A neuropsychological analysis of memory loss with age , 1988, Neurobiology of Aging.

[70]  C. A. O'Malley,et al.  Effects of ovariectomy and estradiol benzoate on high affinity choline uptake, ACh synthesis, and release from rat cerebral cortical synaptosomes , 1987, Brain Research.

[71]  V. Luine Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats , 1985, Experimental Neurology.

[72]  G. Winocur The hippocampus and thalamus: Their roles in short- and long-term memory and the effects of interference , 1985, Behavioural Brain Research.

[73]  G. Winocur The effects of retroactive and proactive interference on learning and memory in old and young rats. , 1984, Developmental psychobiology.

[74]  B. McEwen,et al.  Sex differences in cholinergic enzymes of diagonal band nuclei in the rat preoptic area. , 1983, Neuroendocrinology.

[75]  R. Butcher,et al.  Follicular and plasma patterns of steroids in young and old rats during normal and prolonged estrous cycles. , 1982, Biology of reproduction.

[76]  R. Morris,et al.  Place navigation impaired in rats with hippocampal lesions , 1982, Nature.

[77]  H. Shore,et al.  Estrogen for older women. , 1973, American journal of obstetrics and gynecology.

[78]  S. Campbell,et al.  Oestrogen therapy and the menopausal syndrome. , 1969, Clinics in obstetrics and gynaecology.

[79]  J. Daniel,et al.  Estradiol replacement enhances working memory in middle-aged rats when initiated immediately after ovariectomy but not after a long-term period of ovarian hormone deprivation. , 2006, Endocrinology.

[80]  F. Craik,et al.  The Oxford handbook of memory , 2006 .

[81]  H. C. Coelingh Bennink Are all estrogens the same? , 2004, Maturitas.

[82]  Donna L Korol,et al.  Estrogen-induced changes in place and response learning in young adult female rats. , 2002, Behavioral neuroscience.

[83]  M. Anthony,et al.  Effects of long-term hormone replacement and of tibolone on choline acetyltransferase and acetylcholinesterase activities in the brains of ovariectomized, cynomologus monkeys. , 2002, Neuroscience.

[84]  M. Gass Hormonal replacement therapy. , 1999, Southern medical journal.

[85]  R. Williams,et al.  Williams Textbook of endocrinology , 1985 .

[86]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .

[87]  B. Underwood Interference and forgetting. , 1957, Psychological review.