Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation.
暂无分享,去创建一个
Andrea C. Carrano | M. Pagano | A. Montagnoli | A. Hershko | G. Draetta | M Pagano | A Hershko | G F Draetta | A. Carrano | A Montagnoli | F Fiore | E Eytan | A C Carrano | F. Fiore | E. Eytan | Francesca Fiore
[1] P. Seth,et al. Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27. , 1997, Cancer research.
[2] G. Hannon. Expression of Cell Cycle Proteins Using Recombinant Baculoviruses , 1996 .
[3] R. Pepperkok,et al. Cyclin A is required at two points in the human cell cycle. , 1992, The EMBO journal.
[4] Stephen J. Elledge,et al. The SCFβ-TRCP–ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro , 1999 .
[5] Bruno Amati,et al. Phosphorylation‐dependent degradation of the cyclin‐dependent kinase inhibitor p27Kip1 , 1997, The EMBO journal.
[6] B. Lim,et al. IκB Is a Substrate for a Selective Pathway of Lysosomal Proteolysis , 1998 .
[7] Philip D. Jeffrey,et al. Crystal structure of the p27Kip1 cyclin-dependent-kinase inibitor bound to the cyclin A–Cdk2 complex , 1996, Nature.
[8] P. Beer-Romero,et al. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. , 1995, Science.
[9] C. Pickart. Targeting of substrates to the 26S proteasome , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[10] D. Morgan,et al. Activation of human cyclin-dependent kinases in vitro. , 1992, Molecular biology of the cell.
[11] James M. Roberts,et al. Cyclin E-CDK2 is a regulator of p27Kip1. , 1997, Genes & development.
[12] A. Hershko,et al. Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[13] M. Pagano,et al. Differential expression and regulation of Cyclin D1 protein in normal and tumor human cells: association with Cdk4 is required for Cyclin D1 function in G1 progression. , 1994, Oncogene.
[14] A. Hershko,et al. Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates. , 1985, Biochemical and biophysical research communications.
[15] Patrick M. O'Connor,et al. Synchronization of Mammalian Cells , 1996 .
[16] M. Pagano,et al. The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. , 1999, Oncogene.
[17] A. Koff,et al. Cell-Free Degradation of p27kip1, a G1 Cyclin-Dependent Kinase Inhibitor, Is Dependent on CDK2 Activity and the Proteasome , 1999, Molecular and Cellular Biology.
[18] T. Hunt,et al. The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase. , 1996, The EMBO journal.
[19] M. Pagano,et al. Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation , 1997, Leukemia.
[20] D. Beach,et al. p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase. , 1987, The EMBO journal.
[21] M. Roussel,et al. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[22] B. Lim,et al. IkappaB is a substrate for a selective pathway of lysosomal proteolysis. , 1998, Molecular biology of the cell.
[23] James M. Roberts,et al. Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade. , 1998, Molecular cell.
[24] James M. Roberts,et al. IS023 Cleavage of p21^ and p27^ Mediates Apoptosis in Endothelial Cells Through Activation of Cdk2: Role of a Caspase-3-like Caspase Cascade , 1998 .
[25] J. Potashkin,et al. Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2 + and suc1 + , 1987, Cell.
[26] Joe Rodriguez,et al. Dismantling Cell–Cell Contacts during Apoptosis Is Coupled to a Caspase-dependent Proteolytic Cleavage of β-Catenin , 1997, The Journal of cell biology.
[27] J. Massagué,et al. Differential Interaction of the Cyclin-dependent Kinase (Cdk) Inhibitor p27Kip1 with Cyclin A-Cdk2 and Cyclin D2-Cdk4* , 1997, The Journal of Biological Chemistry.
[28] S. Elledge,et al. The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro. , 1999, Genes & development.
[29] James M. Roberts,et al. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition , 1995, Molecular and cellular biology.
[30] A. Ciechanover,et al. Inhibition of NF‐κB cellular function via specific targeting of the IκB‐ubiquitin ligase , 1997 .
[31] M. Loda,et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas , 1997, Nature Medicine.
[32] M. Pagano,et al. Cell cycle regulation by the ubiquitin pathway , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[33] W. Ansorge,et al. Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes , 1997, Oncogene.
[34] J. Pines. Regulation of the G2 to M transition. , 1998, Results and problems in cell differentiation.
[35] L. Hengst,et al. Translational Control of p27Kip1 Accumulation During the Cell Cycle , 1996, Science.
[36] J. Roberts,et al. Regulation of G1 phase. , 1998, Results and problems in cell differentiation.
[37] James M. Roberts,et al. Cloning of p27 Kip1 , a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals , 1994, Cell.
[38] S. van den Heuvel,et al. Distinct roles for cyclin-dependent kinases in cell cycle control. , 1993, Science.
[39] L. Meijer. Chemical inhibitors of cyclin-dependent kinases. , 1996, Trends in cell biology.
[40] M. Pagano,et al. Enhanced Ribosomal Association of p27Kip1 mRNA Is a Mechanism Contributing to Accumulation during Growth Arrest* , 1997, The Journal of Biological Chemistry.
[41] Yung-Hyun Choi,et al. Regulation of Cyclin D1 by Calpain Protease* , 1997, The Journal of Biological Chemistry.
[42] Kim Nasmyth,et al. Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle , 1994, Cell.
[43] R Pepperkok,et al. Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts , 1993, The Journal of cell biology.
[44] M. Tyers,et al. Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis. , 1998, Trends in genetics : TIG.
[45] E. Sausville,et al. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. , 1996, Cancer research.
[46] Tony Hunter,et al. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21 , 1994, Cell.
[47] M. Kubbutat,et al. Keeping an old friend under control: regulation of p53 stability. , 1998, Molecular medicine today.