Fabrication of 3D Scaffolds with Precisely Controlled Substrate Modulus and Pore Size by Templated‐Fused Deposition Modeling to Direct Osteogenic Differentiation

Scaffolds with tunable mechanical and topological properties fabricated by templated-fused deposition modeling promote increased osteogenic differentiation of bone marrow stem cells with increasing substrate modulus and decreasing pore size. These findings guide the rational design of cell-responsive scaffolds that recapitulate the bone microenvironment for repair of bone damaged by trauma or disease.

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