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Genomics: The search for association

The list of human genetic variations is expanding; but an understanding of how they contribute to disease is still patchy.

Monya Baker | M. Baker

[1] K. Mossman. The Wellcome Trust Case Control Consortium, U.K. , 2008 .

[2] P. Shannon,et al. Exome sequencing identifies the cause of a Mendelian disorder , 2009, Nature Genetics.

[3] V. Salomaa,et al. Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia , 2010, Nature Genetics.

[4] H. Stefánsson,et al. Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma , 2010, Nature Genetics.

[5] Sharon R Grossman,et al. Integrating common and rare genetic variation in diverse human populations , 2010, Nature.

[6] John Wei,et al. Towards a comprehensive structural variation map of an individual human genome , 2010, Genome Biology.

[7] Jake K. Byrnes,et al. Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls , 2010 .

[8] Tanya M. Teslovich,et al. Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids , 2010, Nature.

[9] Nilanjan Chatterjee,et al. Estimation of effect size distribution from genome-wide association studies and implications for future discoveries , 2010, Nature Genetics.

[10] M. Daly,et al. Common SNPs in HMGCR in Micronesians and Whites Associated With LDL-Cholesterol Levels Affect Alternative Splicing of Exon13 , 2008, Arteriosclerosis, thrombosis, and vascular biology.