Frog larvae cloned from nuclei of pronephric adenocarcinoma.

Abstract Triploid nuclei of epithelial cell cultures derived from a viral induced frog pronephric carcinoma were injected into enucleated eggs of Rana pipiens . Formation of triploid post-neurulae and larvae free of tumors, attests to the genetic pluripotency and reversibility of nuclei from pronephric carcinoma.

[1]  B. Mintz,et al.  Teratocarcinomas and other neoplasms as developmental defects in gene expression. , 1981, Advances in cancer research.

[2]  M. Diberardino.  Genetic stability and modulation of metazoan nuclei transplanted into eggs and oocytes. , 1980, Differentiation; research in biological diversity.

[3]  M. Diberardino,et al.  Developmental potential of somatic nuclei transplanted into meiotic oocytes of Rana pipiens. , 1980, Science.

[4]  DiBerardino Ma.  Nuclear and chromosomal behavior in amphibian nuclear transplants. , 1979 .

[5]  M. Diberardino,et al.  Methods for studying nucleocytoplasmic exchange of nonhistone proteins in embryos. , 1977, Methods in cell biology.

[6]  K. Illmensee,et al.  Totipotency and normal differentiation of single teratocarcinoma cells cloned by injection into blastocysts. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[7]  I. Toplin,et al.  Tumor Induction in Developing Frog Kidneys by a Zonal Centrifuge Purified Fraction of the Frog Herpes-Type Virus , 1969, Science.

[8]  R. McKinnell,et al.  Transplantation of Pluripotential Nuclei from Triploid Frog Tumors , 1969, Science.

[9]  M. Diberardino,et al.  Chromosome Studies of Primary Renal Carcinoma from Vermont Rana pipiens , 1969 .

[10]  T. J. King.  Chapter 1 Nuclear Transplantation in Amphibia , 1966 .

[11]  T. J. King,et al.  TRANSPLANTATION OF NUCLEI FROM THE FROG RENAL ADENOCARCINOMA I. DEVELOPMENT OF TUMOR NUCLEAR‐TRANSPLANT EMBRYOS * , 1965, Annals of the New York Academy of Sciences.

[12]  T. J. King,et al.  TRANSPLANTATION OF NUCLEI FROM THE FROG RENAL ADENOCARCINOMA. II. CHROMOSOMAL AND HISTOLOGIC ANALYSIS OF TUMOR NUCLEAR-TRANSPLANT EMBRYOS. , 1965, Developmental biology.

[13]  G. B. Pierce,et al.  MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS. , 1964, Cancer research.

[14]  R. McKinnell.  Intraspecific nuclear transplantation in frogs. , 1962, The Journal of heredity.

[15]  M. A. D. Berardino.  The karyotype of Rana pipiens and investigation of its stability during embryonic differentiation , 1962 .

[16]  R. Briggs,et al.  Serial transplantation of embryonic nuclei. , 1956, Cold Spring Harbor symposia on quantitative biology.

[17]  R. Briggs,et al.  Transplantation of Living Nuclei From Blastula Cells into Enucleated Frogs' Eggs. , 1952, Proceedings of the National Academy of Sciences of the United States of America.

[18]  R. Briggs,et al.  An investigation of the capacity for cleavage and differentiation in Rana pipiens eggs lacking "functional" chromosomes. , 1951, The Journal of experimental zoology.

[19]  W. Shumway.  Stages in the normal development of Rana pipiens I. External form , 1940 .