Feed Forward Neural Network for Autofluorescence Imaging Classification

The key elements in cancer diagnostics are the early identification and estimation of the tumor growth anditsspreadinordertodeterminetheareatobeoperatedon. Theaimofourstudywastodevelopnewmethodsof analyzing autofluorescence images which will allow us an objective and accurate assessment of the locationof a tumor and will also be helpful in determining the advancement of the disease. The proposed classificationmethods are based on neural network algorithms. An Olympus company endoscopic system was used for anautofluorescence intestine imaging study. The autofluorescence imaging analysis process can be divided intoseveral main stages. The first step is preparation of a training data set. The second one involves selection offeaturespace, namelytheselectionof thosefeatureswhichenabledistinguishing thepathologicallyalteredareasfromthehealthyones. Finalstagesoftheanalysisincludepathologicallychangedtissueclassificationanddiagnosis.PACSnumbers:87.57.

[1]  M. Wallace,et al.  Identification of predictive factors for early neoplasia in Barrett's esophagus after autofluorescence imaging: a stepwise multicenter structured assessment. , 2009, Gastrointestinal endoscopy.

[2]  Haishan Zeng,et al.  Real‐time endoscopic fluorescence imaging for early cancer detection in the gastrointestinal tract , 1998 .

[3]  Anke Meyer-Bäse Pattern recognition for medical imaging , 2003 .

[4]  B Palcic,et al.  Detection and localization of early lung cancer by imaging techniques. , 1993, Chest.

[5]  B. Tabachnick,et al.  Using Multivariate Statistics , 1983 .

[6]  N. Uedo,et al.  A novel videoendoscopy system by using autofluorescence and reflectance imaging for diagnosis of esophagogastric cancers. , 2005, Gastrointestinal endoscopy.

[7]  Paul Fockens,et al.  Endoscopic video autofluorescence imaging may improve the detection of early neoplasia in patients with Barrett's esophagus. , 2005, Gastrointestinal endoscopy.

[9]  Mohammad Bagher Menhaj,et al.  Training feedforward networks with the Marquardt algorithm , 1994, IEEE Trans. Neural Networks.

[10]  Thomas D Wang,et al.  Autofluorescence imaging: have we finally seen the light? , 2005, Gastrointestinal endoscopy.

[11]  A Coldman,et al.  Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy. , 1998, Chest.

[12]  E. Dekker,et al.  Hyperplastic polyposis syndrome: a pilot study for the differentiation of polyps by using high-resolution endoscopy, autofluorescence imaging, and narrow-band imaging. , 2009, Gastrointestinal endoscopy.