Knee-to-Ankle Mosaicplasty for the Treatment of Osteochondral Lesions of the Ankle Joint

Background Osteochondral lesions are frequently seen in athletes after ankle injuries. At this time, osteochondral autologous transplantation (OATS, mosaicplasty) is the only surgical treatment that replaces the entire osteochondral unit in symptomatic lesions. Purpose To evaluate the clinical and radiological midterm to long-term outcome of ankles treated with knee-to-ankle mosaicplasty. Study Design Case series; Level of evidence, 4. Methods Clinical evaluation consisted of patient satisfaction, pain evaluation (visual analog scale [VAS]), American Orthopaedic Foot and Ankle Society (AOFAS) ankle score, sports activity score, range of motion, the radiological evaluation of magnetic resonance imaging (MRI), and single photon emission computed tomography–computed tomography (SPECT-CT) analysis of both the ankle and the knee joint. Results Twelve of 21 patients (mean age, 43 years; male, 8; female, 4) were available for latest follow-up (mean, 72 months). At follow-up, patients reported a satisfaction rate of good to excellent in 92% (n 5 11) and poor in 8% (n 5 1). The average VAS pain score was 3.9 (preoperative, 5.9; P 5 .02), AOFAS ankle score significantly increased from 45.9 to 80.2 points (P< .0001), sports activity score remained significantly decreased with 1.25 (preinjury level, 2.3; P 5 .035), and ankle dorsiflexion was significantly reduced (P 5 .003). Knee pain was reported in 6 patients (50%). Radiologically, recurrent lesions were found in 10 of 10 cases (100%) and some degree of cartilage degeneration and discontinuity of the subchondral bone plate in 100%. Conclusion Indications for mosaicplasty with a plug transfer from the knee to the talus must be considered carefully, as at midterm, moderate outcome and considerable donor-site morbidity may be found.

[1]  M. Rynn,et al.  Osteochondral lesions of the talus. , 1983, The Journal of foot surgery.

[2]  R. Al-Shaikh,et al.  Autologous Osteochondral Grafting for Talar Cartilage Defects , 2002, Foot & ankle international.

[3]  T. Brown,et al.  Incongruity-dependent Changes of Contact Stress Rates in Human Cadaveric Ankles , 2006, Journal of orthopaedic trauma.

[4]  J. Haberstroh,et al.  Articular cartilage degeneration after acute subchondral bone damage An experimental study in dogs with histopathological grading , 2004 .

[5]  S. Roberts,et al.  Early results of autologous chondrocyte implantation in the talus. , 2005, The Journal of bone and joint surgery. British volume.

[6]  G. Sammarco,et al.  Treatment of Talar Osteochondral Lesions Using Local Osteochondral Graft , 2002, Foot & ankle international.

[7]  M. Dijkgraaf,et al.  Prospective study on diagnostic strategies in osteochondral lesions of the talus. Is MRI superior to helical CT? , 2005, The Journal of bone and joint surgery. British volume.

[8]  R. Ferkel,et al.  Arthroscopic debridement and drilling of osteochondral lesions of the talus. , 2003, Foot and ankle clinics.

[9]  C. Gottlob,et al.  Arthroscopically Assisted Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talar Dome: An MRI and Clinical Follow-Up Study , 2001, Foot & ankle international.

[10]  Torsten Kuwert,et al.  Skeletal SPECT/CT of the peripheral extremities. , 2010, AJR. American journal of roentgenology.

[11]  V. Valderrábano,et al.  Radiographic evaluation of frontal talar edge configuration for osteochondral plug transplantation , 2009, Clinical anatomy.

[12]  W Herzog,et al.  Inadequate placement of osteochondral plugs may induce abnormal stress-strain distributions in articular cartilage --finite element simulations. , 2002, Medical engineering & physics.

[13]  P. Niemeyer,et al.  Mosaicplasty with Autogenous Talar Autograft for Osteochondral Lesions of the Talus after Failed Primary Arthroscopic Management , 2006, The American journal of sports medicine.

[14]  A. Cole,et al.  Cultured human ankle and knee cartilage differ in susceptibility to damage mediated by fibronectin fragments , 1998, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[15]  A. Cole,et al.  Human knee and ankle cartilage explants: Catabolic differences , 2002, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[16]  B. Hintermann,et al.  Sports and Recreation Activity of Ankle Arthritis Patients before and after Total Ankle Replacement , 2006, The American journal of sports medicine.

[17]  藤井 唯誌 The manual stress test may not be sufficient to differentiate ankle ligament injuries , 2001 .

[18]  J. Lysholm,et al.  Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale , 1982, The American journal of sports medicine.

[19]  A. Cole,et al.  Comparison of biomechanical and biochemical properties of cartilage from human knee and ankle pairs , 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[20]  P. Scranton,et al.  Outcome of osteochondral autograft transplantation for type-V cystic osteochondral lesions of the talus. , 2006, The Journal of bone and joint surgery. British volume.

[21]  B. Sennett,et al.  The Morbidity Associated with Osteochondral Harvest from Asymptomatic Knees for the Treatment of Osteochondral Lesions of the Talus , 2007, The American journal of sports medicine.

[22]  J. Jerosch,et al.  The cartilage of the tibiofibular joint: a source for autologous osteochondral grafts without damaging weight-bearing joint surfaces , 2002, Archives of Orthopaedic and Trauma Surgery.

[23]  Patrick O. McKeon,et al.  Dorsiflexion deficit during jogging with chronic ankle instability. , 2009, Journal of science and medicine in sport.

[24]  Michael Harty,et al.  Transchondral fractures (osteochondritis dissecans) of the talus. , 1959, The Journal of bone and joint surgery. American volume.

[25]  R. Jakob,et al.  Treatment of cartilage defects of the talus by autologous osteochondral grafts. , 2002, The Journal of bone and joint surgery. British volume.

[26]  A. Baltzer,et al.  Bone-cartilage transplantation from the ipsilateral knee for chondral lesions of the talus. , 2005, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[27]  S. Conti,et al.  Retrograde Drilling of Osteochondral Lesions of the Medial Talar Dome , 1999, Foot & ankle international.

[28]  I. Berkes,et al.  Development of a New Activity Score for the Evaluation of Ankle Instability , 2004, The American journal of sports medicine.

[29]  K. Athanasiou,et al.  Biomechanical topography of human ankle cartilage , 1995, Annals of Biomedical Engineering.

[30]  L. Hangody,et al.  Autologous Osteochondral Mosaicplasty for the Treatment of Full-Thickness Defects of Weight-Bearing Joints: Ten Years of Experimental and Clinical Experience , 2003, The Journal of bone and joint surgery. American volume.

[31]  J. Nunley,et al.  Clinical Rating Systems for the Ankle-Hindfoot, Midfoot, Hallux, and Lesser Toes , 1994, Foot & ankle international.

[32]  P. Bossuyt,et al.  Systematic review of treatment strategies for osteochondral defects of the talar dome. , 2003, Foot and ankle clinics.

[33]  J. Lubowitz,et al.  Osteochondral lesions of the talus: randomized controlled trial comparing chondroplasty, microfracture, and osteochondral autograft transplantation. , 2006, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[34]  R. Haut,et al.  The extent and distribution of cell death and matrix damage in impacted chondral explants varies with the presence of underlying bone. , 2003, Journal of biomechanical engineering.

[35]  M. Wimmer,et al.  Impaction affects cell viability in osteochondral tissues during transplantation. , 2010, The journal of knee surgery.

[36]  Benno M Nigg,et al.  Kinematic Changes After Fusion and Total Replacement of the Ankle Part 1: Range of Motion , 2003, Foot & ankle international.

[37]  D. Clement,et al.  Nonoperatively Managed Stage 5 Osteochondral Talar Lesions , 2002, Foot & ankle international.

[38]  Magnetic Resonance Imaging of Articular Cartilage , 2001, Clinical orthopaedics and related research.

[39]  Sylvia Ounpuu,et al.  The effect of walking speed on lower-extremity joint powers among elderly adults who exhibit low physical performance. , 2005, Archives of physical medicine and rehabilitation.

[40]  Takashi Nakamura,et al.  Bony lesion recurrence after mosaicplasty for osteochondritis dissecans of the talus. , 2005, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[41]  C. Lee,et al.  Osteochondral Autografts for Osteochondritis Dissecans of the Talus , 2003, Foot & ankle international.

[42]  Benno M Nigg,et al.  Kinematic Changes After Fusion and Total Replacement of the Ankle Part 2: Movement Transfer , 2003, Foot & ankle international.

[43]  M. Müller-Gerbl Introduction (Review of Literature) , 1998 .

[44]  M. Müller-Gerbl The Subchondral Bone Plate , 1998, Advances in Anatomy Embryology and Cell Biology.

[45]  L. Hangody,et al.  Mosaicplasty for the Treatment of Osteochondritis Dissecans of the Talus: Two to Seven Year Results in 36 Patients , 2001, Foot & ankle international.

[46]  W. Bautz,et al.  Skeletal SPECT/CT of the peripheral extremities -interdisciplinary approach in orthopaedic disorders-first clinical results , 2007 .