Dual response of calpain to rat brain postdecapitative ischemia.

[1]  L. Venance,et al.  Biosynthesis of an Endogenous Cannabinoid Precursor in Neurons and its Control by Calcium and cAMP , 1996, The Journal of Neuroscience.

[2]  F. Grynspan,et al.  Regional differences in gene expression for calcium activated neutral proteases (calpains) and their endogenous inhibitor calpastatin in mouse brain and spinal cord. , 1996, Journal of neurobiology.

[3]  T. Zalewska,et al.  Autophosphorylation as a possible mechanism of calcium/calmodulin-dependent protein kinase II inhibition during ischemia , 1996, Neurochemistry International.

[4]  G. Lynch,et al.  Time-Related Neuronal Changes following Middle Cerebral Artery Occlusion: Implications for Therapeutic Intervention and the Role of Calpain , 1995, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[5]  R. Bartus,et al.  Calpain as a novel target for treating acute neurodegenerative disorders. , 1995, Neurological research.

[6]  M. Nakamura,et al.  Subcellular Distribution of Calpain and Calpastatin Immunoreactivity and Fodrin Proteolysis in Rabbit Hippocampus After Hypoxia and Glucocorticoid Treatment , 1994, Journal of neurochemistry.

[7]  H. Sorimachi,et al.  Calpain: new perspectives in molecular diversity and physiological‐pathological involvement , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[8]  R. Bartus,et al.  Postischemic Administration of AK275, a Calpain Inhibitor, Provides Substantial Protection against Focal Ischemic Brain Damage , 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[9]  R. Siman,et al.  Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[10]  KEVIN S. Lee,et al.  Neuroprotection With a Calpain Inhibitor in a Model of Focal Cerebral Ischemia , 1994, Stroke.

[11]  P. Andiné,et al.  Upregulation of calpain activity in neonatal rat brain after hypoxic-ischemia , 1993, Brain Research.

[12]  K. Suzuki,et al.  Spatial resolution of fodrin proteolysis in postischemic brain. , 1993, The Journal of biological chemistry.

[13]  K. Domanska-Janik,et al.  Protein kinase C as an early and sensitive marker of ischemia-induced progressive neuronal damage in gerbil hippocampus. , 1993, Molecular and chemical neuropathology.

[14]  H. Kawasaki,et al.  Muscle-specific calpain, p94, is degraded by autolysis immediately after translation, resulting in disappearance from muscle. , 1993, The Journal of biological chemistry.

[15]  J. Krieglstein,et al.  Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo , 1993, Brain Research.

[16]  K. Suzuki,et al.  In situ capture of mu-calpain activation in platelets. , 1993, The Journal of biological chemistry.

[17]  T. Mcintosh,et al.  Measurement of Hippocampal Levels of Cellular Second Messengers Following In Situ Freezing , 1993, Journal of neurochemistry.

[18]  T. Zalewska,et al.  Is calpain activity regulated by membranes and autolysis or by calcium and calpastatin? , 1992, BioEssays : news and reviews in molecular, cellular and developmental biology.

[19]  R. Nixon,et al.  Immunoassay and Activity of Calcium‐Activated Neutral Proteinase (mCANP): Distribution in Soluble and Membrane‐Associated Fractions in Human and Mouse Brain , 1992, Journal of neurochemistry.

[20]  G. Lynch,et al.  Inhibition of proteolysis protects hippocampal neurons from ischemia. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[21]  G. Demartino,et al.  Calcium-activated neutral protease (calpain) system: structure, function, and regulation. , 1991, Physiological reviews.

[22]  J. Karlsson,et al.  Changes in brain calpain activity as a result of in vitro ischemia and pH alterations. , 1991, Molecular and chemical neuropathology.

[23]  G. Lynch,et al.  Calpain inhibitors improve the recovery of synaptic transmission from hypoxia in hippocampal slices , 1990, Brain Research.

[24]  K. Suzuki,et al.  Calcium activated neutral protease--structure-function relationship and functional implications. , 1990, Cell structure and function.

[25]  M. Nakamura,et al.  Properties of erythrocyte membrane binding and autolytic activation of calcium-activated neutral protease. , 1989, The Journal of biological chemistry.

[26]  D. E. Goll,et al.  Effect of Ca2+ on binding of the calpains to calpastatin. , 1989, The Journal of biological chemistry.

[27]  F. Wolfe,et al.  Chicken skeletal muscle has three Ca2+-dependent proteinases. , 1989, Biochimica et biophysica acta.

[28]  G. Lynch,et al.  Ischemia triggers NMDA receptor-linked cytoskeletal proteolysis in hippocampus , 1989, Brain Research.

[29]  K. Suzuki,et al.  Tandemly reiterated negative enhancer-like elements regulate transcription of a human gene for the large subunit of calcium-dependent protease. , 1989, The Journal of biological chemistry.

[30]  E. Hogan,et al.  Calcium‐activated neutral proteinase in rat brain myelin and subcellular fractions , 1988, Journal of neuroscience research.

[31]  R. Mellgren,et al.  Calcium‐dependent proteases: an enzyme system active at cellular membranes? , 1987, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[32]  K. Imahori,et al.  Endogenous inhibitor for calcium-dependent cysteine protease contains four internal repeats that could be responsible for its multiple reactive sites. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[33]  R. Kannagi,et al.  Repetitive region of calpastatin is a functional unit of the proteinase inhibitor. , 1987, Biochemical and biophysical research communications.

[34]  S. Barsky,et al.  Hydrophobic association of calpains with subcellular organelles. Compartmentalization of calpains and the endogenous inhibitor calpastatin in tissues. , 1986, The Journal of biological chemistry.

[35]  H. Towbin,et al.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[36]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[37]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[38]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[39]  T. Zalewska.  Calpain as proposed target for neuroprotective treatment of brain ischemia. , 1996, Folia neuropathologica.

[40]  K. Suzuki,et al.  Autolytic transition of mu-calpain upon activation as resolved by antibodies distinguishing between the pre- and post-autolysis forms. , 1992, Journal of biochemistry.

[41]  T. Zalewska,et al.  Calcium-dependent proteolytic activity in hypoxic rat brain. , 1989, Biomedica biochimica acta.

[42]  K. Blomgren,et al.  Calpain and calpastatin levels in different organs of the rabbit. , 1989, Comparative biochemistry and physiology. B, Comparative biochemistry.

[43]  H. Kawasaki,et al.  Regulation of activity of calcium activated neutral protease. , 1988, Advances in enzyme regulation.

[44]  K. Imahori,et al.  Purification and Characterization of a Calcium-Activated Neutral Protease from Rabbit Skeletal Muscle which Requires Calcium Ions of μM Order Concentration , 1983 .