Dissecting the conformational complexity and mechanism of a bacterial heme transporter
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G. Hummer | A. Mehdipour | T. Grund | F. Finke | D. Bald | H. G. Goojani | S. Safarian | R. Zimmermann | Di Wu | Mark Shepherd | Roan R Groh | Sonja Welsch | Thomas M B Reichhart
[1] G. Hummer,et al. Evidence for a trap-and-flip mechanism in a proton-dependent lipid transporter , 2021, Nature Communications.
[2] H. Schwalbe,et al. Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli , 2021, Proceedings of the National Academy of Sciences.
[3] S. Safarian,et al. Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase , 2021, Nature Communications.
[4] Aurélien F. A. Moumbock,et al. Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D , 2021, Nature Communications.
[5] G. Hummer,et al. The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB , 2021, Nature Communications.
[6] L. Guddat,et al. Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels , 2021, Nature Communications.
[7] M. Lienemann. Molecular mechanisms of electron transfer employed by native proteins and biological-inorganic hybrid systems , 2020, Computational and structural biotechnology journal.
[8] T. Stockner,et al. The role of the degenerate nucleotide binding site in type I ABC exporters , 2020, FEBS letters.
[9] E. Tajkhorshid,et al. Structural and functional diversity calls for a new classification of ABC transporters , 2020, FEBS letters.
[10] E. Nudler,et al. CydDC functions as a cytoplasmic cystine reductase to sensitize Escherichia coli to oxidative stress and aminoglycosides , 2020, Proceedings of the National Academy of Sciences.
[11] Li Zhang. Heme Biology , 2020 .
[12] J. Kowal,et al. Structure of the human lipid exporter ABCB4 in a lipid environment , 2019, Nature Structural & Molecular Biology.
[13] D. Bald,et al. Cytochrome bd in Mycobacterium tuberculosis: A respiratory chain protein involved in the defense against antibacterials. , 2019, Progress in biophysics and molecular biology.
[14] B. Böttcher,et al. Homologous bd oxidases share the same architecture but differ in mechanism , 2019, Nature Communications.
[15] R. Gennis,et al. Active site rearrangement and structural divergence in prokaryotic respiratory oxidases , 2019, Science.
[16] G. Hummer,et al. Conformation space of a heterodimeric ABC exporter under turnover conditions , 2019, Nature.
[17] G. Hummer,et al. Inward-facing conformation of a multidrug resistance MATE family transporter , 2019, Proceedings of the National Academy of Sciences.
[18] Thorsten Wagner,et al. SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM , 2019, Communications Biology.
[19] Jue Chen,et al. Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation , 2018, Science.
[20] T. Walz,et al. Structural basis of MsbA-mediated lipopolysaccharide transport , 2017, Nature.
[21] D. Agard,et al. MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy , 2017, Nature Methods.
[22] A. Maresso,et al. A dual component heme biosensor that integrates heme transport and synthesis in bacteria. , 2015, Journal of microbiological methods.
[23] Berk Hess,et al. GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers , 2015 .
[24] Kai Zhang,et al. Gctf: Real-time CTF determination and correction , 2015, bioRxiv.
[25] Elizabeta Nemeth,et al. Iron homeostasis in host defence and inflammation , 2015, Nature reviews. Immunology.
[26] Sunhwan Jo,et al. CHARMM‐GUI Membrane Builder toward realistic biological membrane simulations , 2014, J. Comput. Chem..
[27] R. Gennis,et al. Subunit CydX of Escherichia coli cytochrome bd ubiquinol oxidase is essential for assembly and stability of the di‐heme active site , 2014, FEBS letters.
[28] Roberto L. Mempin,et al. Release of extracellular ATP by bacteria during growth , 2013, BMC Microbiology.
[29] Sjors H.W. Scheres,et al. RELION: Implementation of a Bayesian approach to cryo-EM structure determination , 2012, Journal of structural biology.
[30] A. Arutyunyan,et al. Optical and magneto-optical activity of cytochrome bd from Geobacillus thermodenitrificans. , 2012, Biochimica et biophysica acta.
[31] M. Hohl,et al. Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation , 2012, Nature Structural &Molecular Biology.
[32] H. Michel,et al. The Structure of cbb3 Cytochrome Oxidase Provides Insights into Proton Pumping , 2010, Science.
[33] M. Meyerson,et al. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP , 2008, Proceedings of the National Academy of Sciences.
[34] Lutz Schmitt,et al. The motor domains of ABC-transporters , 2006, Naunyn-Schmiedeberg's Archives of Pharmacology.
[35] R. Poole,et al. Membrane topology and mutational analysis of Escherichia coli CydDC, an ABC-type cysteine exporter required for cytochrome assembly. , 2004, Microbiology.
[36] R. Huber,et al. Structure and mechanism of the aberrant ba3‐cytochrome c oxidase from Thermus thermophilus , 2000, The EMBO journal.
[37] N. Andrews. Iron metabolism: iron deficiency and iron overload. , 2000, Annual review of genomics and human genetics.
[38] B. Goldman,et al. Use of heme reporters for studies of cytochrome biosynthesis and heme transport , 1996, Journal of bacteriology.
[39] B. Goldman,et al. The temperature-sensitive growth and survival phenotypes of Escherichia coli cydDC and cydAB strains are due to deficiencies in cytochrome bd and are corrected by exogenous catalase and reducing agents , 1996, Journal of bacteriology.
[40] P. Lindley,et al. Iron in biology: a structural viewpoint , 1996 .
[41] G. Wu,et al. The cydD gene product, component of a heterodimeric ABC transporter, is required for assembly of periplasmic cytochrome c and of cytochrome bd in Escherichia coli. , 1994, FEMS microbiology letters.
[42] G. Cox,et al. Cytochrome bd biosynthesis in Escherichia coli: the sequences of the cydC and cydD genes suggest that they encode the components of an ABC membrane transporter , 1993, Molecular microbiology.
[43] H. Williams,et al. Investigation of the role of the cydD gene product in production of a functional cytochrome d oxidase in Escherichia coli. , 1993, FEMS microbiology letters.
[44] R. Gennis,et al. Identification of the cydC locus required for expression of the functional form of the cytochrome d terminal oxidase complex in Escherichia coli , 1987, Journal of bacteriology.