Dementia and Art: Neuronal Intermediate Filament Inclusion Disease and Dissolution of Artistic Creativity

The paper presents a new case of neuronal intermediate filament inclusion disease (NIFID), a recently described new variant of early-onset frontotemporal dementia. Documented with repetitive brain images, morphologically proven cases additionally endorse evolving the clinical and pathological phenotype of NIFID. For the first time the paper describes the probable influence of NIFID on the artistic creativity of an accomplished artist showing rapid dissolution of artistic talent.

[1]  B. Miller,et al.  Portraits of artists: emergence of visual creativity in dementia. , 2004, Archives of neurology.

[2]  D. Dickson,et al.  Extending the clinicopathological spectrum of neurofilament inclusion disease , 2005, Acta Neuropathologica.

[3]  B L Miller,et al.  Emergence of artistic talent in frontotemporal dementia , 1998, Neurology.

[4]  B. Miller,et al.  Enhanced artistic creativity with temporal lobe degeneration , 1996, The Lancet.

[5]  L. Fornazzari,et al.  Preserved painting creativity in an artist with Alzheimer's disease , 2005, European journal of neurology.

[6]  N. Gordon.  Unexpected development of artistic talents , 2005, Postgraduate Medical Journal.

[7]  Martin N Rossor,et al.  Some workmen can blame their tools: artistic change in an individual with Alzheimer's disease , 2001, The Lancet.

[8]  Julien Bogousslavsky,et al.  Artistic Creativity, Style and Brain Disorders , 2005, European Neurology.

[9]  S. DeKosky,et al.  NIFID: a new molecular pathology with a frontotemporal dementia phenotype. , 2004, Neurology.

[10]  A. Lang,et al.  Neurodegenerative disease and the evolution of art: The effects of presumed corticobasal degeneration in a professional artist , 2003, Movement Disorders.

[11]  L. Sivik,et al.  Colour discrimination, colour naming and colour preferences among individuals with Alzheimer's disease , 1999, International journal of geriatric psychiatry.

[12]  H. Feldman,et al.  Neurofilament inclusion body disease with early onset frontotemporal dementia and primary lateral sclerosis. , 2004, Clinical neuropathology.

[13]  C. H Espinel,et al.  de Kooning's late colours and forms: dementia, creativity, and the healing power of art , 1996, The Lancet.

[14]  K. Maurer,et al.  Paintings of an artist with Alzheimer’s disease: visuoconstructural deficits during dementia , 2004, Journal of Neural Transmission.

[15]  B. Miller,et al.  Art and the brain , 2003, Neurology.

[16]  J. Cummings,et al.  Probable Alzheimer's disease in an artist. , 1987, JAMA.

[17]  J. Trojanowski,et al.  Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease , 2004, Neurology.

[18]  K. Boone,et al.  Neuroanatomy of the self: Evidence from patients with frontotemporal dementia , 2001 .

[19]  C. O'Brien.  Auguste D. and Alzheimer's Disease , 1996, Science.

[20]  D. Sahlas.  Dementia with Lewy bodies and the neurobehavioral decline of Mervyn Peake. , 2003, Archives of neurology.

[21]  M. Mendez.  Dementia as a window to the neurology of art. , 2004, Medical hypotheses.

[22]  Nick C Fox,et al.  Neurofilament inclusion body disease: a new proteinopathy? , 2003, Brain : a journal of neurology.