Supporting measurements or more averages? How to quantify cerebral blood flow most reliably in 5 minutes by arterial spin labeling

To determine whether sacrificing part of the scan time of pseudo‐continuous arterial spin labeling (PCASL) for measurement of the labeling efficiency and blood T1 is beneficial in terms of CBF quantification reliability.

[1]  Marta Vidorreta,et al.  Improving the robustness of pseudo‐continuous arterial spin labeling to off‐resonance and pulsatile flow velocity , 2017, Magnetic resonance in medicine.

[2]  Emily Kilroy,et al.  Reliability of two‐dimensional and three‐dimensional pseudo‐continuous arterial spin labeling perfusion MRI in elderly populations: Comparison with 15o‐water positron emission tomography , 2014, Journal of magnetic resonance imaging : JMRI.

[3]  J A Frank,et al.  Effect of restricted water exchange on cerebral blood flow values calculated with arterial spin tagging: A theoretical investigation , 2000, Magnetic resonance in medicine.

[4]  N. Otsu A threshold selection method from gray level histograms , 1979 .

[5]  Matthias Günther,et al.  T2‐based arterial spin labeling measurements of blood to tissue water transfer in human brain , 2013, Journal of magnetic resonance imaging : JMRI.

[6]  Maolin Qiu,et al.  Arterial transit time effects in pulsed arterial spin labeling CBF mapping: Insight from a PET and MR study in normal human subjects , 2010, Magnetic resonance in medicine.

[7]  Fenella J Kirkham,et al.  A general model to calculate the spin-lattice (T1) relaxation time of blood, accounting for haematocrit, oxygen saturation and magnetic field strength , 2016, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[8]  Chun Yuan,et al.  Measuring the labeling efficiency of pseudocontinuous arterial spin labeling , 2017, Magnetic resonance in medicine.

[9]  Santiago Aja-Fernández,et al.  Spatially variant noise estimation in MRI: A homomorphic approach , 2015, Medical Image Anal..

[10]  Lutz Tellmann,et al.  Comparison of cerebral blood flow acquired by simultaneous [15O]water positron emission tomography and arterial spin labeling magnetic resonance imaging , 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[11]  Michael A. Chappell,et al.  A general framework for optimizing arterial spin labeling MRI experiments , 2018, Magnetic resonance in medicine.

[12]  J. Sijbers,et al.  The costs and benefits of estimating T1 of tissue alongside cerebral blood flow and arterial transit time in pseudo‐continuous arterial spin labeling , 2020 .

[13]  Jun Hua,et al.  Measurement of absolute arterial cerebral blood volume in human brain without using a contrast agent , 2011, NMR in biomedicine.

[14]  Norbert Schuff,et al.  Four‐phase single‐capillary stepwise model for kinetics in arterial spin labeling MRI , 2005, Magnetic resonance in medicine.

[15]  J. Sijbers,et al.  The costs and benefits of estimating T 1 of tissue alongside cerebral blood flow and arterial transit time in pseudo‐continuous arterial spin labeling , 2019, NMR in biomedicine.

[16]  Weiying Dai,et al.  Volumetric measurement of perfusion and arterial transit delay using hadamard encoded continuous arterial spin labeling , 2013, Magnetic resonance in medicine.

[17]  G. Zaharchuk,et al.  Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia. , 2015, Magnetic resonance in medicine.

[18]  A Koo,et al.  On-line measurement of the dynamic velocity of erythrocytes in the cerebral microvessels in the rat. , 1974, Microvascular research.

[19]  Peiying Liu,et al.  Fast measurement of blood T1 in the human carotid artery at 3T: Accuracy, precision, and reproducibility , 2017, Magnetic resonance in medicine.

[20]  Feng Xu,et al.  Estimation of labeling efficiency in pseudocontinuous arterial spin labeling , 2010, Magnetic resonance in medicine.

[21]  Xavier Golay,et al.  Determining the longitudinal relaxation time (T1) of blood at 3.0 Tesla , 2004, Magnetic resonance in medicine.

[22]  J. Detre,et al.  Impact of equilibrium magnetization of blood on ASL quantification , 2010 .

[23]  Hesamoddin Jahanian,et al.  Comparison of cerebral blood flow measurement with [15O]-water positron emission tomography and arterial spin labeling magnetic resonance imaging: A systematic review , 2016, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[24]  J. Detre,et al.  A theoretical and experimental investigation of the tagging efficiency of pseudocontinuous arterial spin labeling , 2007, Magnetic resonance in medicine.

[25]  Eidrees Ghariq,et al.  Time‐encoded pseudocontinuous arterial spin labeling: Basic properties and timing strategies for human applications , 2014, Magnetic resonance in medicine.

[26]  Alain Lalande,et al.  What are normal relaxation times of tissues at 3 T? , 2017, Magnetic resonance imaging.

[27]  M. V. van Osch,et al.  Advances in arterial spin labelling MRI methods for measuring perfusion and collateral flow , 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[28]  Kim Mouridsen,et al.  The QUASAR reproducibility study, Part II: Results from a multi-center Arterial Spin Labeling test–retest study , 2010, NeuroImage.

[29]  J. Detre,et al.  Cerebral perfusion and arterial transit time changes during task activation determined with continuous arterial spin labeling , 2000, Magnetic resonance in medicine.

[30]  Danny J J Wang,et al.  A two‐stage approach for measuring vascular water exchange and arterial transit time by diffusion‐weighted perfusion MRI , 2012, Magnetic resonance in medicine.

[31]  Youngkyoo Jung,et al.  Multiphase pseudocontinuous arterial spin labeling (MP‐PCASL) for robust quantification of cerebral blood flow , 2010, Magnetic resonance in medicine.

[32]  D. Alsop,et al.  Continuous flow‐driven inversion for arterial spin labeling using pulsed radio frequency and gradient fields , 2008, Magnetic resonance in medicine.

[33]  R. Spencer,et al.  Fisher information and Cramér‐Rao lower bound for experimental design in parallel imaging , 2018, Magnetic resonance in medicine.

[34]  M J Welch,et al.  Positron Emission Tomographic Measurement of Cerebral Blood Flow and Permeability—Surface Area Product of Water Using [15O]Water and [11C]Butanol , 1987, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[35]  Matthias Günther,et al.  Improving perfusion quantification in arterial spin labeling for delayed arrival times by using optimized acquisition schemes. , 2015, Zeitschrift fur medizinische Physik.

[36]  G. Pawlik,et al.  Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study , 1981, Brain Research.

[37]  Aart J. Nederveen,et al.  Accuracy and precision of pseudo-continuous arterial spin labeling perfusion during baseline and hypercapnia: A head-to-head comparison with 15O H2O positron emission tomography , 2014, NeuroImage.

[38]  S Warach,et al.  A general kinetic model for quantitative perfusion imaging with arterial spin labeling , 1998, Magnetic resonance in medicine.

[39]  R Bowtell,et al.  Modeling and optimization of look‐locker spin labeling for measuring perfusion and transit time changes in activation studies taking into account arterial blood volume , 2008, Magnetic resonance in medicine.

[40]  Mark W. Woolrich,et al.  Variational Bayesian Inference for a Nonlinear Forward Model , 2020, IEEE Transactions on Signal Processing.

[41]  B. Fenton,et al.  Microcirculatory model relating geometrical variation to changes in pressure and flow rate , 1981, Annals of Biomedical Engineering.

[42]  Peter C M van Zijl,et al.  Quantitative theory for the longitudinal relaxation time of blood water , 2016, Magnetic resonance in medicine.

[43]  S. H. Koenig,et al.  Magnetic-field-dependent water proton spin-lattice relaxation rates of hemoglobin solutions and whole blood☆ , 1974 .

[44]  Daniel Gallichan,et al.  Bayesian inference of hemodynamic changes in functional arterial spin labeling data , 2006, Magnetic resonance in medicine.

[45]  M. Reisert,et al.  Blood Tracer Kinetics in the Arterial Tree , 2014, PloS one.

[46]  Laura M Parkes,et al.  Improved accuracy of human cerebral blood perfusion measurements using arterial spin labeling: Accounting for capillary water permeability , 2002, Magnetic resonance in medicine.

[47]  John A. Detre,et al.  Comparison of 2D and 3D single-shot ASL perfusion fMRI sequences , 2013, NeuroImage.