Use of sensor-augmented insulin pump in patient with diabetes and cystic fibrosis: evidence for improvement in metabolic control.

Cystic fibrosis-related diabetes (CFRD) is a frequent complication of cystic fibrosis. We report the significant improvement of diabetes control and quality of life in a CFRD patient using the sensor-augmented insulin pump. The system gives the patient the highest degree of flexibility, which is required in CFRD since food intake and activity levels vary widely from day to day, depending on the rapid changes of health status.

[1]  R. Shamir,et al.  Impaired gastric myolectrical activity in patients with cystic fibrosis. , 2006, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[2]  B. Thorsteinsson,et al.  Influence of the development of diabetes mellitus on clinical status in patients with cystic fibrosis , 1992, European Journal of Pediatrics.

[3]  N. Sulli,et al.  Use of continuous subcutaneous insulin infusion in patients with cystic fibrosis related diabetes: three case reports. , 2007, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[4]  E. Mathiesen,et al.  Cystic Fibrosis–Related Diabetes , 2006, Diabetes Care.

[5]  M. Stanton,et al.  Cystic fibrosis mortality and survival in the UK: 1947–2003 , 2007, European Respiratory Journal.

[6]  Y. Berthiaume,et al.  Diabetes: a major co-morbidity of cystic fibrosis. , 2005, Diabetes & metabolism.

[7]  T. Rochat,et al.  Electrogastrography Reveals Post-prandial Gastric Dysmotility in Children with Cystic Fibrosis , 2004, Journal of pediatric gastroenterology and nutrition.

[8]  S. Daniel Infection and inflammation CF: management of the basics upper airway diseases. , 2006, Paediatric respiratory reviews.

[9]  S. Bell,et al.  Microvascular complications in cystic fibrosis-related diabetes mellitus: a case report. , 2000, JOP : Journal of the pancreas.

[10]  S. Finkelstein,et al.  Diabetes mellitus associated with cystic fibrosis. , 1988, The Journal of pediatrics.

[11]  J. Rosenecker,et al.  Diabetes mellitus in patients with cystic fibrosis: the impact of diabetes mellitus on pulmonary function and clinical outcome. , 2001, European journal of medical research.

[12]  A. S. Neri,et al.  Use of continuous subcutaneous insulin infusion in cystic fibrosis patients with cystic fibrosis-related diabetes awaiting transplantation. , 2006, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[13]  F. Kaufman,et al.  A pilot trial in pediatrics with the sensor-augmented pump: combining real-time continuous glucose monitoring with the insulin pump. , 2007, The Journal of pediatrics.

[14]  S. Conway,et al.  Diagnosis and Treatment of Intestinal Malabsorption in Cystic Fibrosis , 2006, Pediatric pulmonology.

[15]  A. Parant,et al.  Cystic fibrosis mortality trends in France. , 2007, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.