Synthesis and structure-activity relationships of new β-adrenoreceptor antagonists. Evidence for the electrostatic requirements for β-adrenoreceptor antagonists
暂无分享,去创建一个
[1] V. Kettmann,et al. Structure of ethyl 2‐[(2‐hydroxy‐3‐isopropylamino)propoxy]carbanilate hydrochloride , 1989 .
[2] P. Carrupt,et al. Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists. , 1988, Journal of medicinal chemistry.
[3] R. Boča. Inclusion of relativistic effects into ZDO methods. I. A quasi‐relativistic CNDO/1 , 1987 .
[4] J. Binet,et al. Synthesis of a series of compounds related to betaxolol, a new beta 1-adrenoceptor antagonist with a pharmacological and pharmacokinetic profile optimized for the treatment of chronic cardiovascular diseases. , 1987, Journal of medicinal chemistry.
[5] Adriaan P. IJzerman,et al. Factors controlling β1-adrenoceptor affinity and selectivity , 1985 .
[6] P. Maroko,et al. Comparative Effects of Dobutamine and Corwin, a β1‐Adrenergic Partial Agonist, in Experimental Left Ventricular Failure , 1985, Journal of cardiovascular pharmacology.
[7] M. Remko,et al. Ab initio investigations on the local anesthetics procaine, lidocaine and heptacaine , 1983 .
[8] W. Eckelman,et al. Cardioselectivity of beta-adrenoceptor blocking agents. 2. Role of the amino group substituent. , 1983, Journal of medicinal chemistry.
[9] Peter A. Kollman,et al. AMBER: Assisted model building with energy refinement. A general program for modeling molecules and their interactions , 1981 .
[10] H. Tucker. Beta-adrenergic blocking agents. 20. (3-Hydroxyprop-1-enyl)-substituted 1-(aryloxy)-3-(alkylamino)propan-2-ols. , 1980, Journal of medicinal chemistry.
[11] P. D. de Feyter,et al. Clinical, Electrocardiographic, and Hemodynamic Effects of ICI 89,406, a New Cardioselective Beta‐Adrenoceptor Antagonist with Intrinsic Sympathomimetic Activity, in Patients with Angina Pectoris , 1980, Journal of cardiovascular pharmacology.
[12] W. Frishman. Clinical pharmacology of the new beta-adrenergic blocking drugs. Part 13. The beta-adrenoceptor blocking drugs: a perspective. , 1980, American heart journal.
[13] M Karplus,et al. Side-chain torsional potentials: effect of dipeptide, protein, and solvent environment. , 1979, Biochemistry.
[14] F. Weinhold,et al. Quantum-mechanical studies on the origin of barriers to internal rotation about single bonds , 1979 .
[15] D. Mackay. How should values of pA2 and affinity constants for pharmacological competitive antagonists be estimated? , 1978, The Journal of pharmacy and pharmacology.
[16] G. Shtacher,et al. Cardioselectivity as a function of molecular structure in beta-adrenoceptor blocking agents of the 1-(para-substituted aryloxy)-3-(isopropylamino)propan-2-ol type. , 1978, Journal of medicinal chemistry.
[17] D. Azarnoff,et al. Pamatolol: Phase I evaluation of the pharmacodynamics of a cardioselective beta adrenoceptor blocking drug , 1978, Clinical pharmacology and therapeutics.
[18] Norman L. Allinger,et al. Conformational analysis. 130. MM2. A hydrocarbon force field utilizing V1 and V2 torsional terms , 1977 .
[19] M. Burke-Laing,et al. Structures of nitrogen-containing aromatic compounds. III. Benzalazine, redetermination and refinement , 1976 .
[20] Claude Giessner-Prettre,et al. On the molecular electrostatic potentials obtained from CNDO wave functions , 1975 .
[21] A. Holmes,et al. Cardioselective beta-adrenergic blocking agents. 1. 1-((3,4-Dimethoxyphenethyl)amino)-3-aryloxy-2-propanols. , 1975, Journal of medicinal chemistry.
[22] Charles Tanford,et al. Theory of micelle formation in aqueous solutions , 1974 .
[23] D. Maxwell,et al. β‐Adrenoceptor blocking properties and cardioselectivity of M & B 17,803A , 1973, British journal of pharmacology.
[24] C. Giessner-Prettre,et al. Molecular electrostatic potentials: Comparison of ab initio and CNDO results , 1972 .
[25] L. H. Smith,et al. Beta-adrenergic blocking agents. 10. (3-amino-2-hydroxypropoxy)anilides. , 1971, Journal of medicinal chemistry.
[26] L. H. Amundsen,et al. Rearrangements of o-Aminophenyl Esters , 1966 .
[27] H. Jaffe,et al. Theory and Applications of Ultraviolet Spectroscopy , 1962 .
[28] K. Takagi,et al. Chemicopharmacological Studies on Antispasmodic Action. XV. Non-specific Antispasmodic Action on Tracheal Muscle. , 1958 .
[29] C. E. Slimowicz,et al. Preparation and Properties of Certain Alkyl Azamalonates , 1949 .
[30] F. Brown,et al. The Friedel—Crafts Reaction with o-Nitrophenol and Acyl Halides1 , 1946 .
[31] A. Martinelli,et al. MO STUDIES ON THE MECHANISM OF DRUG RECEPTOR INTERACTION .4. INTERACTING CONFORMATIONS OF BETA-ADRENERGIC DRUGS , 1983 .
[32] A. Martinelli,et al. Ab initio study of the internal rotation and of the electrostatic molecular potential of a model compound of tazolol and comparison with similar compounds , 1980 .