Liver injury: Light and Dark Side of Herbal Formulations

Global burden of liver diseases responsible for more than two million deaths annually, that presents a significant health concern worldwide. The practice of natural products or herbal formulations to treat ailments started with the evolution of human civilization.Traditional herbs are tremendous remedies for the treatment of liver diseases and WHO reported that majority of the population in Asian and African content using natural formulations for liver disorders like fatty liver diseases. Due to the unavailability of regulatory agencies guidelines and standard bylaws to maintain the quality, safety and efficacy of herbal medicines especially in the underdeveloped as well as developing countries, many herbal formulations making companies advertise that herbal medicines do not induce any adverse effect and even a number of people are attracted by these companies and using herbal medicines. There are several reasons such as self-treatment, improper intake, sub-standard product, unqualified practitioners are the reasons for toxicity of herbal formulations. This review summarizes the dark and light side of herbal formulations in liver injury.

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