Effects of anti-inflammatory drugs following cataract extraction

Cycloplegics, corticosteroids, and nonsteroidal anti-inflammatory drugs have been applied in the treatment of postoperative inflammation following cataract extraction. Of these, topical preparations of nonsteroidal anti-inflammatory drugs, such as ketorolac tromethamine 0.5% and diclofenac sodium 0.1%, offer comparable efficacy to corticosteroids in the reduction of postoperative inflammation, and offer lower risks of adverse events in most patients. Comparative studies of these drugs from the past 5 years are highlighted.

[1]  J. Heier,et al.  Control of intraocular inflammation associated with cataract surgery. , 2000, Current opinion in ophthalmology.

[2]  J. Jenkins,et al.  Comparison of the efficacy and safety of ketorolac tromethamine 0.5% and prednisolone acetate 1% after cataract surgery. , 1999, Journal of cataract and refractive surgery.

[3]  A. Flach,et al.  Comparative effects of ketorolac 0.5% or diclofenac 0.1% ophthalmic solutions on inflammation after cataract surgery. , 1998, Ophthalmology.

[4]  A. Chuang,et al.  A randomized double-masked trial comparing ketorolac tromethamine 0.5%, diclofenac sodium 0.1%, and prednisolone acetate 1% in reducing post-phacoemulsification flare and cells. , 1998, Ophthalmic surgery and lasers.

[5]  P. Denis,et al.  The Effects of Rimexolone 1% in Postoperative Inflammation after Cataract Extraction. A Double-Masked Placebo-Controlled Study , 1998, European journal of ophthalmology.

[6]  H. Sutton,et al.  Topical Diclofenac Sodium Compared with Prednisolone Acetate after Phacoemulsification-Lens Implant Surgery , 1997, European journal of ophthalmology.

[7]  G. Massry,et al.  Control of ocular inflammation after cataract extraction with rimexolone 1% ophthalmic suspension , 1997, Journal of cataract and refractive surgery.

[8]  R. Masi,et al.  Ketorolac, prednisolone, and dexamethasone for postoperative inflammation. , 1997, Clinical therapeutics.

[9]  Gimbel Hv,et al.  Effects of cycloplegia and iris pigmentation on postoperative intraocular inflammation. , 1993, Ophthalmic surgery.

[10]  M. Abelson,et al.  Conjunctivitis of allergic origin: immunologic mechanisms and current approaches to therapy. , 1993, Survey of ophthalmology.

[11]  A. Flach,et al.  The effect of ketorolac tromethamine solution 0.5% in reducing postoperative inflammation after cataract extraction and intraocular lens implantation. , 1988, Ophthalmology.

[12]  A. Schweizer,et al.  Pharmacology of diclofenac sodium. , 1986, The American journal of medicine.

[13]  G. Singh Corticosteroids in corneal endothelial wound healing. , 1985, Annals of ophthalmology.

[14]  M. Kass,et al.  Flurbiprofen and intraocular pressure. , 1981, Annals of Ophthalmology.

[15]  M. Greaves,et al.  Itch: Role of Prostaglandins , 1973, British medical journal.

[16]  M. Knopf A double-blind study of fluorometholone. , 1970, American journal of ophthalmology.

[17]  P C Kronfeld,et al.  The Protein Content of the Reformed Aqueous Humor in Man. , 1941, Transactions of the American Ophthalmological Society.

[18]  V. Hessemer,et al.  [Minor effect of anti-inflammatory therapy on intraocular inflammation after minimally invasive phacoemulsification]. , 1997, Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft.

[19]  N. Orzalesi,et al.  Effectiveness of diclofenac eyedrops in reducing inflammation and the incidence of cystoid macular edema after cataract surgery , 1996, Journal of cataract and refractive surgery.

[20]  A. Flach Cyclo-oxygenase inhibitors in ophthalmology. , 1992, Survey of ophthalmology.

[21]  R. Hyndiuk,et al.  Infectious conjunctivitis. , 1992, Infectious disease clinics of North America.

[22]  A. Flach Treatment of Postoperative Inflammation in Ophthalmology , 1991 .

[23]  R. Beuerman,et al.  Effects of steroidal and non-steroidal anti-inflammatory agents on corneal wound healing. , 1987, Journal of ocular pharmacology.

[24]  M. Friedlaender Corticosteroid therapy of ocular inflammation. , 1983, International ophthalmology clinics.