Early interpersonal violence mediates the effect of family history of mental disorder on suicide attempts in a non-clinical sample.

BACKGROUND Suicide is a leading cause of death worldwide, with several risk factors, including a family history of mental disorders (FHMD) and interpersonal violence. The relationship between these risk factors needs further investigation. AIM Addressing the impact of interpersonal violence on suicide attempts, and its interaction with FHMD. METHODS 192 participants completed an online questionnaire, including the Psychological Maltreatment Review and the Karolinska Interpersonal Violence Scale (putative mediating variables variables), questions about previous suicide attempts and FHMD. Logistic regression and mediation analysis were performed. RESULTS FHMD (OR=7.09, 95%CI [2.20,22.81]), expressed violence in childhood (OR=2.55, 95%CI [1.26,5.18]) and exposure to violence in childhood (OR=2.80, 95%CI [1.80,4.34]) predicted attempted suicide. Exposure to, and expression of violence in childhood mediated 15.23% and 9.63% respectively of the total effect of FHPD on attempted suicide. LIMITATIONS Small sample size, reporting bias on FHMD an attempted suicide, self-selection bias due to sampling technique. CONCLUSIONS The familial load on adult suicidal behavior is partially mediated by exposure to violence in childhood, suggesting that the presence of a relative affected by any psychiatric condition may contribute to exposure to violence in childhood, which eventually enhances the risk of suicide in adulthood.

[1]  P. Stratta,et al.  From Basic Human Values to Interpersonal Violence: A Mental Illness Sample , 2020, Journal of Aggression, Maltreatment & Trauma.

[2]  A. Rossi,et al.  Interpersonal violence: identification of associated features in a clinical sample. , 2018, Child abuse & neglect.

[3]  G. Bersani,et al.  Il suicidio assistito degli italiani in Svizzera e il silenzio della psichiatria , 2018 .

[4]  F. Pacitti,et al.  From Adolescent Neurogenesis to Schizophrenia: Opportunities, Challenges and Promising Interventions , 2018 .

[5]  P. Stratta,et al.  Different roles of resilience in depressive patients with history of suicide attempt and no history of suicide attempt , 2017, Revista brasileira de psiquiatria.

[6]  M. Åsberg,et al.  Combining the Suicide Intent Scale and the Karolinska Interpersonal Violence Scale in suicide risk assessments , 2015, BMC Psychiatry.

[7]  T. Hirvikoski,et al.  Family history of suicide and exposure to interpersonal violence in childhood predict suicide in male suicide attempters. , 2013, Journal of affective disorders.

[8]  Theo Vos,et al.  The Long-Term Health Consequences of Child Physical Abuse, Emotional Abuse, and Neglect: A Systematic Review and Meta-Analysis , 2012, PLoS medicine.

[9]  N. Godbout,et al.  The Psychological Maltreatment Review (PMR): Initial Reliability and Association with Insecure Attachment in Adults , 2012 .

[10]  M. Åsberg,et al.  Karolinska Interpersonal Violence Scale predicts suicide in suicide attempters. , 2010, The Journal of clinical psychiatry.

[11]  Matthew K Nock,et al.  Suicide and suicidal behavior. , 2008, Epidemiologic reviews.

[12]  J. Pirkis,et al.  Global trends in suicide epidemiology , 2017, Current opinion in psychiatry.

[13]  A. Mack The Interaction of Parental History of Suicidal Behavior and Exposure to Adoptive Parents' Psychiatric Disorders on Adoptee Suicide Attempt Hospitalizations , 2013 .

[14]  G. Liotti TRAUMA, DISSOCIATION, AND DISORGANIZED ATTACHMENT: THREE STRANDS OF A SINGLE BRAID , 2004 .

[15]  Z. A. Trapeznikova On the Interaction of , 1959 .