Differential regulation of Wnt/beta-catenin signaling by Liver X Receptors in Schwann cells and oligodendrocytes.

[1]  J. Gustafsson,et al.  Liver X receptor β protects dopaminergic neurons in a mouse model of Parkinson disease , 2012, Proceedings of the National Academy of Sciences.

[2]  Tomas Jakobsson,et al.  Liver X receptor biology and pharmacology: new pathways, challenges and opportunities. , 2012, Trends in pharmacological sciences.

[3]  M. Ameloot,et al.  Liver X receptors regulate cholesterol homeostasis in oligodendrocytes , 2012, Journal of neuroscience research.

[4]  V. Leoni,et al.  Oxysterols as biomarkers in neurodegenerative diseases. , 2011, Chemistry and physics of lipids.

[5]  W. Sierralta,et al.  27-hydroxycholesterol induces the transition of MCF7 cells into a mesenchymal phenotype. , 2011, Oncology reports.

[6]  M. Schumacher,et al.  Interplay between LXR and Wnt/β-Catenin Signaling in the Negative Regulation of Peripheral Myelin Genes by Oxysterols , 2011, The Journal of Neuroscience.

[7]  M. García-Villanueva,et al.  A novel myelin protein zero (V136G) homozygous mutation causing late onset demyelinating polyneuropathy with brain white matter lesions , 2011, Clinical Neurology and Neurosurgery.

[8]  M. Schumacher,et al.  Wnt/β-Catenin Signaling Is an Essential and Direct Driver of Myelin Gene Expression and Myelinogenesis , 2011, The Journal of Neuroscience.

[9]  A. Faden,et al.  Modulation of ABCA1 by an LXR agonist reduces β-amyloid levels and improves outcome after traumatic brain injury. , 2011, Journal of neurotrauma.

[10]  K. Davis,et al.  Peripheral myelin protein-22 is expressed in CNS myelin , 2010, Translational neuroscience.

[11]  R. Ostrowski,et al.  Activation of liver X receptor reduces global ischemic brain injury by reduction of nuclear factor-κB , 2010, Neuroscience.

[12]  E. Mazzon,et al.  Liver X receptor agonist treatment regulates inflammatory response after spinal cord trauma , 2010, Journal of neurochemistry.

[13]  M. Schumacher,et al.  Cross-Talk between Oxysterols and Glucocorticoids: Differential Regulation of Secreted Phopholipase A2 and Impact on Oligodendrocyte Death , 2009, PloS one.

[14]  Andrew J. Brown,et al.  Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis. , 2009, Molecular aspects of medicine.

[15]  R. Moon,et al.  Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis , 2009, Cell Research.

[16]  M. Schumacher,et al.  25‐hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR , 2009, Journal of neurochemistry.

[17]  M. Makishima,et al.  Suppression of beta-catenin signaling by liver X receptor ligands. , 2009, Biochemical pharmacology.

[18]  B. Leber,et al.  O-GlcNAc-glycosylation of beta-catenin regulates its nuclear localization and transcriptional activity. , 2008, Experimental cell research.

[19]  Yimin Zou,et al.  Wnt signaling in neural circuit assembly. , 2008, Annual review of neuroscience.

[20]  P. Arlotta,et al.  Conditional Knock-Out of β-Catenin in Postnatal-Born Dentate Gyrus Granule Neurons Results in Dendritic Malformation , 2007, The Journal of Neuroscience.

[21]  D. Mangelsdorf,et al.  Liver X receptors and cholesterol homoeostasis: spotlight on the adrenal gland. , 2006, Biochemical Society transactions.

[22]  J. Cunningham,et al.  Myelin protein zero mutation His39Pro: hereditary motor and sensory neuropathy with variable onset, hearing loss, restless legs and multiple sclerosis , 2006, Journal of Neurology, Neurosurgery & Psychiatry.

[23]  M. Schumacher,et al.  Differential recruitment of p160 coactivators by glucocorticoid receptor between Schwann cells and astrocytes. , 2006, Molecular endocrinology.

[24]  M. Schumacher,et al.  Involvement of {beta}-catenin and unusual behavior of CBP and p300 in glucocorticosteroid signaling in Schwann cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[25]  R. Mirsky,et al.  The origin and development of glial cells in peripheral nerves , 2005, Nature Reviews Neuroscience.

[26]  J. Gustafsson,et al.  Inactivation of liver X receptor beta leads to adult-onset motor neuron degeneration in male mice. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[27]  M. Schumacher,et al.  Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain Published, JLR Papers in Press, September 1, 2004. DOI 10.1194/jlr.M400244-JLR200 , 2004, Journal of Lipid Research.

[28]  R. Franklin,et al.  The Mysteries of Myelin Unwrapped , 2004, Science.

[29]  T. Sotnikova,et al.  Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[30]  U. Suter,et al.  Instructive Role of Wnt/ß-Catenin in Sensory Fate Specification in Neural Crest Stem Cells , 2004, Science.

[31]  C. Polman,et al.  Decreased levels of the brain specific 24S-hydroxycholesterol and cholesterol precursors in serum of multiple sclerosis patients , 2003, Neuroscience Letters.

[32]  J. Hillert,et al.  Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis , 2002, Neuroscience Letters.

[33]  J. Gustafsson,et al.  Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[34]  P. Patel,et al.  Identification of a positive regulatory element in the myelin‐specific promoter of the PMP22 gene , 2001, Journal of neuroscience research.

[35]  D. Russell,et al.  Oxysterol biosynthetic enzymes. , 2000, Biochimica et biophysica acta.

[36]  F. Berenbaum,et al.  Induction of Secreted Type IIA Phospholipase A2 Gene Transcription by Interleukin-1β , 2000, The Journal of Biological Chemistry.

[37]  F. Jessen,et al.  Plasma 24S‐hydroxycholesterol: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease , 2000, Neuroreport.

[38]  P. Patel,et al.  Glucocorticosteroids stimulate the activity of the promoters of peripheral myelin protein-22 and protein zero genes in Schwann cells , 2000, Brain Research.

[39]  M. Schumacher,et al.  Validation of an analytical procedure to measure trace amounts of neurosteroids in brain tissue by gas chromatography-mass spectrometry. , 2000, Journal of chromatography. B, Biomedical sciences and applications.

[40]  F. Jessen,et al.  Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. , 2000, Journal of lipid research.

[41]  G. Lemke,et al.  Multiple Regulatory Elements Control Transcription of the Peripheral Myelin Protein Zero Gene* , 1997, The Journal of Biological Chemistry.

[42]  D. Mangelsdorf,et al.  Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR. , 1997, Genes & development.

[43]  D. Mangelsdorf,et al.  An oxysterol signalling pathway mediated by the nuclear receptor LXRα , 1996, Nature.

[44]  L. Shaffer,et al.  Duplication of the PMP22 gene in 17p partial trisomy patients with Charcot-Marie-Tooth type-1A neuropathy , 1996, Human Genetics.

[45]  M. Mersel,et al.  Effect of Oxysterol Treatment on Cholesterol Biosynthesis and Reactive Astrocyte Proliferation in Injured Rat Brain Cortex , 1995, Journal of neurochemistry.

[46]  Pierre Bougnères,et al.  Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

[47]  U. Suter,et al.  Pathomechanisms of mutant proteins in Charcot-Marie-Tooth disease , 2007, NeuroMolecular Medicine.

[48]  F. Jessen,et al.  24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. , 2002, Journal of psychiatric research.

[49]  J. Lupski,et al.  Myelin protein zero (MPZ) gene mutations in nonduplication type 1 Charcot‐Marie‐Tooth disease , 1996, Human mutation.