MT1-MMP Initiates Activation of pro-MMP-2 and Integrin αvβ3 Promotes Maturation of MMP-2 in Breast Carcinoma Cells
暂无分享,去创建一个
Jeffrey W. Smith | A. Strongin | B. Ratnikov | E. Deryugina | E. Monosov | R. Discipio | T. I. Postnova
[1] C. Overall,et al. Domain Interactions in the Gelatinase A·TIMP-2·MT1-MMP Activation Complex , 2000, The Journal of Biological Chemistry.
[2] J. Becker,et al. Coexpression of Integrin αvβ3 and Matrix Metalloproteinase-2 (MMP-2) Coincides with MMP-2 Activation: Correlation with Melanoma Progression , 2000 .
[3] H. Birkedal‐Hansen,et al. Inactivating Mutation of the Mouse Tissue Inhibitor of Metalloproteinases-2(Timp-2) Gene Alters ProMMP-2 Activation* , 2000, The Journal of Biological Chemistry.
[4] P. Soloway,et al. TIMP-2 Is Required for Efficient Activation of proMMP-2 in Vivo * , 2000, The Journal of Biological Chemistry.
[5] D. Ruiter,et al. Expression of integrin αvβ3 correlates with activation of membrane‐type matrix metalloproteinase‐1 (MT1‐MMP) and matrix metalloproteinase‐2 (MMP‐2) in human melanoma cells in vitro and in vivo , 2000 .
[6] M. Bernardo,et al. Binding of Active (57 kDa) Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) to Tissue Inhibitor of Metalloproteinase (TIMP)-2 Regulates MT1-MMP Processing and Pro-MMP-2 Activation* , 2000, The Journal of Biological Chemistry.
[7] Jeffrey W. Smith,et al. Functional activation of integrin αvβ3 in tumor cells expressing membrane‐type 1 matrix metalloproteinase , 2000 .
[8] M. Noguchi,et al. Enhanced production and activation of progelatinase A mediated by membrane-type 1 matrix metalloproteinase in human papillary thyroid carcinomas. , 1999, Cancer research.
[9] A. Strongin,et al. Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2. , 1998, Cancer research.
[10] H. Sato,et al. Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells. , 1998, Journal of biochemistry.
[11] Y. Okada,et al. TIMP-2 Promotes Activation of Progelatinase A by Membrane-type 1 Matrix Metalloproteinase Immobilized on Agarose Beads* , 1998, The Journal of Biological Chemistry.
[12] S. Itohara,et al. Reduced angiogenesis and tumor progression in gelatinase A-deficient mice. , 1998, Cancer research.
[13] D. Cheresh,et al. Disruption of Angiogenesis by PEX, a Noncatalytic Metalloproteinase Fragment with Integrin Binding Activity , 1998, Cell.
[14] R. Fridman,et al. Density‐dependent regulation of cell‐surface association of matrix metalloproteinase‐2 (MMP‐2) in breast‐carcinoma cells , 1998, International journal of cancer.
[15] Gillian Murphy,et al. The TIMP2 Membrane Type 1 Metalloproteinase “Receptor” Regulates the Concentration and Efficient Activation of Progelatinase A , 1998, The Journal of Biological Chemistry.
[16] Y. DeClerck,et al. Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Binds to the Catalytic Domain of the Cell Surface Receptor, Membrane Type 1-Matrix Metalloproteinase 1 (MT1-MMP)* , 1998, The Journal of Biological Chemistry.
[17] A. Strongin,et al. Matrix metalloproteinase-2 activation modulates glioma cell migration. , 1997, Journal of cell science.
[18] Jeffrey W. Smith,et al. Identification of a Region in the Integrin β3 Subunit That Confers Ligand Binding Specificity* , 1997, The Journal of Biological Chemistry.
[19] A. Strongin,et al. Tumor cell invasion through matrigel is regulated by activated matrix metalloproteinase-2. , 1997, Anticancer Research.
[20] W. T. Chen,et al. Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[21] P. Phillips,et al. Localization and activation of type IV collagenase/gelatinase at endothelial focal contacts. , 1997, The American journal of physiology.
[22] A. Strongin,et al. A Novel Monoclonal Antibody, L1A3, Is Directed to the Functional Site of the αv Integrin Subunit , 1996 .
[23] G. Butler,et al. The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation , 1996, The Journal of Biological Chemistry.
[24] W. Stetler-Stevenson,et al. Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3 , 1996, Cell.
[25] M. Ramsby,et al. Calibrating gelatin zymograms with human gelatinase standards. , 1996, Analytical biochemistry.
[26] S. Weiss,et al. Transmembrane-deletion Mutants of the Membrane-type Matrix Metalloproteinase-1 Process Progelatinase A and Express Intrinsic Matrix-degrading Activity (*) , 1996, The Journal of Biological Chemistry.
[27] L. Liotta,et al. Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. , 1996, Cancer research.
[28] M. Seiki,et al. Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes (*) , 1995, The Journal of Biological Chemistry.
[29] David A. Cheresh,et al. Definition of Two Angiogenic Pathways by Distinct αv Integrins , 1995, Science.
[30] E. Kohn,et al. Molecular insights into cancer invasion: strategies for prevention and intervention. , 1995, Cancer research.
[31] P. Chambon,et al. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[32] A. Strongin,et al. Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase , 1995, The Journal of Biological Chemistry.
[33] Motoharu Seiki,et al. A matrix metalloproteinase expressed on the surface of invasive tumour cells , 1994, Nature.
[34] W. Stetler-Stevenson,et al. Quantitative zymography: detection of picogram quantities of gelatinases. , 1994, Analytical biochemistry.
[35] A. Strongin,et al. Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2. , 1993, The Journal of biological chemistry.
[36] W. T. Chen,et al. Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia. , 1993, Cancer research.
[37] L. Liotta,et al. Extraction of type‐IV collagenase/gelatinase from plasma membranes of human cancer cells , 1990, International journal of cancer.
[38] A. Eisen,et al. Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[39] I. Hart,et al. Matrix metalloproteinases and metastatic cancer. , 1998, Biochemical Society symposium.
[40] E. Ruoslahti,et al. Integrin signaling and matrix assembly. , 1996, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
[41] L. Coussens,et al. Matrix metalloproteinases and the development of cancer. , 1996, Chemistry & biology.