Peripheral (lung-to-brain) exposure to diesel particulate matter induces oxidative stress and increased markers for systemic inflammation.

[1]  C. Sayes,et al.  An in vitro alveolar model allows for the rapid assessment of chemical respiratory sensitization with modifiable biomarker endpoints. , 2022, Chemico-biological interactions.

[2]  Zhou Yu,et al.  Neuroimmune Crosstalk Between the Peripheral and the Central Immune System in Amyotrophic Lateral Sclerosis , 2022, Frontiers in Aging Neuroscience.

[3]  R. Chang,et al.  The pathogenic effects of particulate matter on neurodegeneration: a review , 2022, Journal of biomedical science.

[4]  Eduardo Tosta.  The seven constitutive respiratory defense barriers against SARS-CoV-2 infection , 2021, Revista da Sociedade Brasileira de Medicina Tropical.

[5]  K. Nakajima,et al.  Inflammatory cytokines TNFα, IL-1β, and IL-6 are induced in endotoxin- stimulated microglia through different signaling cascades , 2021, Science progress.

[6]  C. Cunningham,et al.  Acute neuroinflammation, sickness behavior and working memory responses to acute systemic LPS challenge following noradrenergic lesion in mice , 2020, Brain, Behavior, and Immunity.

[7]  P. Pospíšil,et al.  Reactive Oxygen Species Imaging in U937 Cells , 2020, Frontiers in Physiology.

[8]  Lynne Peeples.  News Feature: How air pollution threatens brain health , 2020, Proceedings of the National Academy of Sciences.

[9]  F. Farina,et al.  Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset , 2020, International journal of molecular sciences.

[10]  D. Schraufnagel.  The health effects of ultrafine particles , 2020, Experimental & Molecular Medicine.

[11]  J. Capelo,et al.  Proteomic changes driven by urban pollution suggest particulate matter as a deregulator of energy metabolism, mitochondrial activity, and oxidative pathways in the rat brain. , 2019, The Science of the total environment.

[12]  J. Schwartz,et al.  Impact of Long-Term Exposures to Ambient PM2.5 and Ozone on ARDS Risk for Older Adults in the United States. , 2019, Chest.

[13]  Y. Jeon,et al.  Beijing urban particulate matter-induced injury and inflammation in human lung epithelial cells and the protective effects of fucosterol from Sargassum binderi (Sonder ex J. Agardh). , 2019, Environmental research.

[14]  M. O’Banion,et al.  Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer’s disease , 2019, Journal of neuroinflammation.

[15]  Biao-Bing Yang,et al.  Effect of PM2.5 environmental pollution on rat lung , 2018, Environmental Science and Pollution Research.

[16]  R. Kulesza,et al.  Hallmarks of Alzheimer disease are evolving relentlessly in Metropolitan Mexico City infants, children and young adults. APOE4 carriers have higher suicide risk and higher odds of reaching NFT stage V at ≤ 40 years of age , 2018, Environmental research.

[17]  M. Tremblay,et al.  Chronic stress as a risk factor for Alzheimer's disease: Roles of microglia-mediated synaptic remodeling, inflammation, and oxidative stress , 2018, Neurobiology of Stress.

[18]  T. Andresen,et al.  Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma , 2017, Scientific Reports.

[19]  T. Morgan,et al.  Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo , 2017, Journal of Neuroinflammation.

[20]  W. Brück,et al.  CD14 is a key organizer of microglial responses to CNS infection and injury , 2016, Glia.

[21]  Moriah L. Szpara,et al.  Differentiation of the SH-SY5Y Human Neuroblastoma Cell Line. , 2016, Journal of visualized experiments : JoVE.

[22]  J. Davis,et al.  Role of MCP-1 on Inflammatory Processes and Metabolic Dysfunction Following High-Fat Feedings in the FVB/N Strain , 2015, International Journal of Obesity.

[23]  K. Tenbrock,et al.  Oxidative stress in multiple sclerosis: Central and peripheral mode of action , 2015, Experimental Neurology.

[24]  E. Fernández,et al.  Particulate Matter from Electronic Cigarettes and Conventional Cigarettes: a Systematic Review and Observational Study , 2015, Current Environmental Health Reports.

[25]  B. Mullins,et al.  The effect of diesel exhaust exposure on blood–brain barrier integrity and function in a murine model , 2015, Journal of applied toxicology : JAT.

[26]  M. Dallas,et al.  Heme oxygenase-1 protects against Alzheimer's amyloid-β1-42-induced toxicity via carbon monoxide production , 2014, Cell Death and Disease.

[27]  C. Lehr,et al.  Overcoming the pulmonary barrier: new insights to improve the efficiency of inhaled therapeutics , 2014 .

[28]  Francesca Granucci,et al.  Role of CD14 in host protection against infections and in metabolism regulation , 2013, Front. Cell. Infect. Microbiol..

[29]  S. Ganesan,et al.  Barrier function of airway tract epithelium , 2013, Tissue barriers.

[30]  F. Pitossi,et al.  Interleukin-1β and tumor necrosis factor-α: reliable targets for protective therapies in Parkinson’s Disease? , 2013, Front. Cell. Neurosci..

[31]  Arno C Gutleb,et al.  An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung , 2013, Particle and Fibre Toxicology.

[32]  J. McDonald,et al.  Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease , 2011, Journal of Neuroinflammation.

[33]  Melinda E. Lull,et al.  Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity , 2011, Environmental health perspectives.

[34]  Qinghua Sun,et al.  Contemporary Reviews in Cardiovascular Medicine Cardiovascular Effects of Ambient Particulate Air Pollution Exposure , 2010 .

[35]  L. Calderón-Garcidueñas,et al.  Air pollution: mechanisms of neuroinflammation and CNS disease , 2009, Trends in Neurosciences.

[36]  S. Amini,et al.  Monocyte chemoattractant protein-1 (MCP-1): an overview. , 2009, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

[37]  H. Erickson.  Size and Shape of Protein Molecules at the Nanometer Level Determined by Sedimentation, Gel Filtration, and Electron Microscopy , 2009, Biological Procedures Online.

[38]  B. McColl,et al.  Systemic Inflammatory Stimulus Potentiates the Acute Phase and CXC Chemokine Responses to Experimental Stroke and Exacerbates Brain Damage via Interleukin-1- and Neutrophil-Dependent Mechanisms , 2007, The Journal of Neuroscience.

[39]  R. Dantzer,et al.  Named Series: Twenty Years of Brain, Behavior, and Immunity Twenty years of research on cytokine-induced sickness behavior , 2007 .

[40]  S. Hester,et al.  The Cellular and Genomic Response of an Immortalized Microglia Cell Line (BV2) to Concentrated Ambient Particulate Matter , 2007, Inhalation toxicology.

[41]  Annette Peters,et al.  Translocation and potential neurological effects of fine and ultrafine particles a critical update , 2006, Particle and Fibre Toxicology.

[42]  J. Finkelstein,et al.  Translocation of Inhaled Ultrafine Manganese Oxide Particles to the Central Nervous System , 2006, Environmental health perspectives.

[43]  N. Rothwell,et al.  The role of inflammation in CNS injury and disease , 2006, British journal of pharmacology.

[44]  G. Oberdörster,et al.  Translocation and effects of ultrafine particles outside of the lung. , 2006, Clinics in occupational and environmental medicine.

[45]  T. Niewold,et al.  Acute phase reaction and acute phase proteins. , 2005, Journal of Zhejiang University. Science. B.

[46]  W. Kreyling,et al.  Translocation of Inhaled Ultrafine Particles to the Brain , 2004, Inhalation toxicology.

[47]  Günter Oberdörster,et al.  Ultrafine particles in the urban air: to the respiratory tract--and beyond? , 2002, Environmental health perspectives.

[48]  R. Dantzer,et al.  Cytokine-induced sickness behaviour: mechanisms and implications , 2002, Trends in Neurosciences.

[49]  J. Schwab,et al.  CD14 expression by activated parenchymal microglia/macrophages and infiltrating monocytes following human traumatic brain injury , 2002, Acta Neuropathologica.

[50]  J. Hogg,et al.  Cytokines involved in the systemic inflammatory response induced by exposure to particulate matter air pollutants (PM(10)). , 2001, American journal of respiratory and critical care medicine.