In vitro neurotoxicity evaluation of biocidal disinfectants in a human neuron-astrocyte co-culture model.

[1]  M. Colasanti,et al.  Amyloid-β 25-35 Induces Neurotoxicity through the Up-Regulation of Astrocytic System Xc− , 2021, Antioxidants.

[2]  Hyun Kil Shin,et al.  Development of blood brain barrier permeation prediction models for organic and inorganic biocidal active substances. , 2021, Chemosphere.

[3]  G. Cortopassi,et al.  Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure , 2021, Toxicology reports.

[4]  T. Slaga,et al.  Safety Assessment of Polyaminopropyl Biguanide (polyhexamethylene biguanide hydrochloride) as Used in Cosmetics , 2017 .

[5]  Yejin Lee,et al.  Mental health impact on a humidifier disinfectant disaster victim: a case report , 2020, Annals of occupational and environmental medicine.

[6]  D. Krewski,et al.  Toxicity testing in the 21st century: progress in the past decade and future perspectives , 2019, Archives of Toxicology.

[7]  C. Baudouin,et al.  Benzalkonium chloride-induced direct and indirect toxicity on corneal epithelial and trigeminal neuronal cells: proinflammatory and apoptotic responses in vitro. , 2019, Toxicology letters.

[8]  Kelly M. Hines,et al.  Multi-omics investigation reveals benzalkonium chloride disinfectants alter sterol and lipid homeostasis in the mouse neonatal brain. , 2019, Toxicological sciences : an official journal of the Society of Toxicology.

[9]  I. Tagkopoulos,et al.  Benzalkonium Chlorides: Uses, Regulatory Status, and Microbial Resistance , 2019, Applied and Environmental Microbiology.

[10]  R. Day,et al.  Mechanisms of Endogenous Neuroprotective Effects of Astrocytes in Brain Injury , 2018, Oxidative medicine and cellular longevity.

[11]  Kira E. Poskanzer,et al.  Dynamism of an Astrocyte In Vivo: Perspectives on Identity and Function. , 2018, Annual review of physiology.

[12]  P. Crettaz,et al.  Developmental neurotoxicity of different pesticides in PC‐12 cells in vitro , 2017, Toxicology and applied pharmacology.

[13]  P. Kunz,et al.  Cytotoxicity and molecular effects of biocidal disinfectants (quaternary ammonia, glutaraldehyde, poly(hexamethylene biguanide) hydrochloride PHMB) and their mixtures in vitro and in zebrafish eleuthero-embryos. , 2017, The Science of the total environment.

[14]  Fang Chen,et al.  Effect of acrylamide-induced neurotoxicity in a primary astrocytes/microglial co-culture model. , 2017, Toxicology in vitro : an international journal published in association with BIBRA.

[15]  Tzong-Der Way,et al.  Efficacy and Safety Evaluation of a Chlorine Dioxide Solution , 2017, International journal of environmental research and public health.

[16]  D. Rohlman,et al.  Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds , 2017, Front. Neurosci..

[17]  C. Murray,et al.  In Vitro activity of Manuka Honey and polyhexamethylene biguanide on filamentous fungi and toxicity to human cell lines , 2016, Medical mycology.

[18]  Jan R. Detrez,et al.  Sustained synchronized neuronal network activity in a human astrocyte co-culture system , 2016, Scientific Reports.

[19]  S. Oredsson,et al.  Acrylamide affects proliferation and differentiation of the neural progenitor cell line C17.2 and the neuroblastoma cell line SH-SY5Y. , 2016, Toxicology in vitro : an international journal published in association with BIBRA.

[20]  N. Schäfer,et al.  Comparing two polymeric biguanides: chemical distinction, antiseptic efficacy and cytotoxicity of polyaminopropyl biguanide and polyhexamethylene biguanide. , 2016, Journal of medical microbiology.

[21]  Fred Parham,et al.  Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity. , 2016, Neurotoxicology.

[22]  Moriah L. Szpara,et al.  Differentiation of the SH-SY5Y Human Neuroblastoma Cell Line. , 2016, Journal of visualized experiments : JoVE.

[23]  Yong-Hwa Kim,et al.  Nationwide Study of Humidifier Disinfectant Lung Injury in South Korea, 1994-2011. Incidence and Dose-Response Relationships. , 2015, Annals of the American Thoracic Society.

[24]  L. Hood,et al.  Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease , 2014, BMC Genomics.

[25]  A. Bansal,et al.  Potassium permanganate toxicity: A rare case with difficult airway management and hepatic damage , 2014, Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine.

[26]  P. Landrigan,et al.  Neurobehavioural effects of developmental toxicity , 2014, The Lancet Neurology.

[27]  L. Smirnova,et al.  Developmental neurotoxicity - challenges in the 21st century and in vitro opportunities. , 2014, ALTEX.

[28]  I. Chiu,et al.  Cytotoxic effects of acrylamide in nerve growth factor or fibroblast growth factor 1-induced neurite outgrowth in PC12 cells , 2013, Archives of Toxicology.

[29]  D. Langford,et al.  Considerations for the use of SH-SY5Y neuroblastoma cells in neurobiology. , 2013, Methods in molecular biology.

[30]  A. Namavari,et al.  Corneal neurotoxicity due to topical benzalkonium chloride. , 2012, Investigative ophthalmology & visual science.

[31]  Marcel Leist,et al.  Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures. , 2011, Toxicological sciences : an official journal of the Society of Toxicology.

[32]  J. Middeldorp,et al.  GFAP in health and disease , 2011, Progress in Neurobiology.

[33]  A. Kramer,et al.  Review on the Efficacy, Safety and Clinical Applications of Polihexanide, a Modern Wound Antiseptic , 2010, Skin Pharmacology and Physiology.

[34]  C. Baudouin,et al.  Preservatives in eyedrops: The good, the bad and the ugly , 2010, Progress in Retinal and Eye Research.

[35]  William R Mundy,et al.  Neuronal models for evaluation of proliferation in vitro using high content screening. , 2010, Toxicology.

[36]  E. Madarász,et al.  Astroglia genesis in vitro: distinct effects of retinoic acid in different phases of neural stem cell differentiaion , 2009, International Journal of Developmental Neuroscience.

[37]  Stella Redpath,et al.  A neuronal and astrocyte co-culture assay for high content analysis of neurotoxicity. , 2009, Journal of visualized experiments : JoVE.

[38]  Timothy J Shafer,et al.  Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.

[39]  William R Mundy,et al.  Developmental neurotoxicity testing in vitro: models for assessing chemical effects on neurite outgrowth. , 2008, Neurotoxicology.

[40]  E. Benarroch,et al.  Neuron-astrocyte interactions: partnership for normal function and disease in the central nervous system. , 2005, Mayo Clinic proceedings.

[41]  D. L. Taylor,et al.  High content screening applied to large-scale cell biology. , 2004, Trends in biotechnology.

[42]  M. Herman,et al.  Class III β-tubulin in human development and cancer† , 2003 .

[43]  P. Yu,et al.  Enhanced tolerance of neuroblastoma cells towards the neurotoxin 6-hydroxydopamine following specific cell–cell interaction with primary astrocytes , 1997, Neuroscience.

[44]  M. Smith,et al.  Effects of chlorine dioxide on the developing rat brain. , 1990, Journal of toxicology and environmental health.

[45]  J. Loeber,et al.  The influence of sodium bromide in man: a study in human volunteers with special emphasis on the endocrine and the central nervous system. , 1983, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.