Current views on the pathophysiology of acute biliary pancreatitis.

rence rate of up to 40%, longterm recurrence rates after sphincteroplasty or sphincterotomy are low.7 Furthermore, studies in animals and humans show that ductal obstruction causes reversible oedema fibrosis and acinar atrophy. Thus Opie's postulates, although nearly 100 years old, for the most part probably hold true8; namely that biliary obstruction is the initiating event in acute biliary pancreatitis.9

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