Touch attenuates infants' physiological reactivity to stress.

Animal studies demonstrate that maternal touch and contact regulate infant stress, and handling during periods of maternal deprivation attenuates the stress response. To measure the effects of touch on infant stress reactivity during simulated maternal deprivation, 53 dyads were tested in two paradigms: still-face (SF) and still-face with maternal touch (SF+T). Maternal and infant cortisol levels were sampled at baseline, reactivity, and recovery and mother's and infant's cardiac vagal tone were measured during the free play, still-face, and reunion episodes of the procedure. Cortisol reactivity was higher among infants in the SF condition and while cortisol decreased at recovery for infants in the SF+T, it further increased for those in the SF. Vagal tone showed a greater suppression when SF was not accompanied by maternal touch. Touch synchrony during free play was associated with higher infant vagal tone, whereas touch myssynchrony--maternal tactile stimulation while the infant gaze averts--correlated with higher maternal and infant cortisol. In humans, as in mammals, the provision of touch during moments of maternal unavailability reduces infants' physiological reactivity to stress.

[1]  T. Field,et al.  Cortisol: The Culprit Prenatal Stress Variable , 2008, The International journal of neuroscience.

[2]  Larry Gray,et al.  Skin-to-Skin Contact Is Analgesic in Healthy Newborns , 2000, Pediatrics.

[3]  R. Feldman,et al.  Skin-to-skin contact (Kangaroo Care) accelerates autonomic and neurobehavioural maturation in preterm infants. , 2003, Developmental medicine and child neurology.

[4]  M. Lamb,et al.  Attachment and bonding: a new synthesis , 2005 .

[5]  E. Tronick,et al.  The mutual regulation model: The infant's self and interactive regulation and coping and defensive capacities. , 1988 .

[6]  S. Porges.  Cardiac vagal tone: A physiological index of stress , 1995, Neuroscience & Biobehavioral Reviews.

[7]  F. Champagne.  Epigenetic mechanisms and the transgenerational effects of maternal care , 2008, Frontiers in Neuroendocrinology.

[8]  S. Levine,et al.  Developmental determinants of sensitivity and resistance to stress , 2005, Psychoneuroendocrinology.

[9]  R. Feldman,et al.  Mother-Child touch patterns in infant feeding disorders: relation to maternal, child, and environmental factors. , 2004, Journal of the American Academy of Child and Adolescent Psychiatry.

[10]  A. Fanaroff.  Maternal Postpartum Behavior and the Emergence of Infant–Mother and Infant–Father Synchrony in Preterm and Full-Term Infants: The Role of Neonatal Vagal Tone , 2008 .

[11]  S. Porges,et al.  Social Engagement and Attachment , 2003, Annals of the New York Academy of Sciences.

[12]  R. Feldman.  Parent-infant synchrony and the construction of shared timing; physiological precursors, developmental outcomes, and risk conditions. , 2007, Journal of child psychology and psychiatry, and allied disciplines.

[13]  John Bowlby,et al.  Attachment and Loss. Vol. I. Attachment. , 1970 .

[14]  A. Weller,et al.  Longitudinal Assessment of Pituitary-Thyroid Axis and Adrenal Function in Preterm Infants Raised by ‘Kangaroo Mother Care’ , 2002, Hormone Research in Paediatrics.

[15]  E. Tronick,et al.  Infant affective reactions to the resumption of maternal interaction after the still-face. , 1996, Child development.

[16]  R. Feldman,et al.  Effects of human contact and vagal regulation on pain reactivity and visual attention in newborns. , 2006, Developmental psychobiology.

[17]  J. Bowlby.  Attachment and loss: retrospect and prospect. , 1969, The American journal of orthopsychiatry.

[18]  Ruth Feldman,et al.  Emotion regulation and touch in infants: the role of cholecystokinin and opioids , 2003, Peptides.

[19]  R. Feldman,et al.  Direct and indirect effects of breast milk on the neurobehavioral and cognitive development of premature infants. , 2003, Developmental psychobiology.

[20]  D. Muir,et al.  Adult tactile stimulation during face-to-face interactions modulates five-month-olds' affect and attention. , 1992, Child development.

[21]  T. Field.  Massage Therapy for Infants and Children , 1995, Journal of developmental and behavioral pediatrics : JDBP.

[22]  Ruth Feldman,et al.  Parent-infant synchrony and the social-emotional development of triplets. , 2004, Developmental psychology.

[23]  G. W. Rever.  Attachment and Loss. Vol. 1. Attachment , 1972 .

[24]  Cathi B. Propper,et al.  Parasympathetic and sympathetic responses to the strange situation in infants and mothers from avoidant and securely attached dyads. , 2008, Developmental psychobiology.

[25]  David W. Haley,et al.  Infant stress and parent responsiveness: regulation of physiology and behavior during still-face and reunion. , 2003, Child development.

[26]  D. Stack,et al.  Functions of maternal touch and infants' affect during face-to-face interactions: new directions for the still-face. , 2009, Infant behavior & development.

[27]  S. Porges,et al.  Vagal reactivity and affective adjustment in infants during interaction challenges. , 2001, Child development.

[28]  M. Hofer.  Hidden regulators: Implications for a new understanding of attachment, separation, and loss. , 1995 .

[29]  R. Feldman,et al.  A neurobiological model for the effects of early brainstem functioning on the development of behavior and emotion regulation in infants: implications for prenatal and perinatal risk. , 2008, Journal of child psychology and psychiatry, and allied disciplines.

[30]  L. Adamson,et al.  The Still Face: A History of a Shared Experimental Paradigm , 2003 .

[31]  M. Lewis,et al.  Infant emotional and cortisol responses to goal blockage. , 2005, Child development.

[32]  S. Porges,et al.  Newborn pain cries and vagal tone: parallel changes in response to circumcision. , 1988, Child development.

[33]  A. Fleming,et al.  Neurobiology of mother–infant interactions: experience and central nervous system plasticity across development and generations , 1999, Neuroscience & Biobehavioral Reviews.

[34]  M. Meaney,et al.  Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. , 2001, Annual review of neuroscience.

[35]  S. Calkins,et al.  Infants' vagal regulation in the still-face paradigm is related to dyadic coordination of mother-infant interaction. , 2004, Developmental psychology.

[36]  Orna Zagoory-Sharon,et al.  Evidence for a Neuroendocrinological Foundation of Human Affiliation , 2007, Psychological science.