Real-time sonoelastography of lateral epicondylitis: comparison of findings between patients and healthy volunteers.

OBJECTIVE The purpose of this study was to evaluate real-time sonoelastography in the assessment of the origins the common extensor tendon in healthy volunteers and in patients with symptoms of lateral epicondylitis. The findings were compared with those obtained at clinical examination, ultrasonography, and power Doppler sonography. SUBJECTS AND METHODS Thirty-eight elbows of 32 consecutively registered patients with symptoms of lateral epicondylitis and 44 asymptomatic elbows of 28 healthy volunteers were assessed with ultrasound and real-time sonoelastography. A clinical examination was performed, and pain was classified with a visual analog scale. RESULTS In healthy volunteers, real-time sonoelastographic images showed hard tendon structures in 96% of tendon thirds and mild alterations in 4%. Real-time sonoelastography of patients showed hard structures in 33% of tendon thirds but softening of different grades in 67%, a statistically significant difference in relation to the findings in healthy volunteers (p < 0.001). Lateral collateral ligament involvement and overlying fascial involvement were more commonly detected with real-time sonoelastography. The sensitivity of real-time sonoelastography was 100%, the specificity 89%, and the accuracy 94% with clinical examination as the reference standard. Good correlation with ultrasound findings was found (r > or = 0.900). No correlation was observed between ultrasound or real-time sonoelastographic findings and power Doppler sonographic findings, but power Doppler sonographic findings had a strong correlation with the visual analog scale score. CONCLUSION Real-time sonoelastography is valuable in the detection of the intratendinous and peritendinous alterations of lateral epicondylitis and facilitates differentiation between healthy and symptomatic extensor tendon origins with excellent sensitivity and excellent correlation with ultrasound findings.

[1]  S. R. Murali,et al.  Steroid injection therapy is the best conservative treatment for lateral epicondylitis: a prospective randomised controlled trial , 2006, International journal of clinical practice.

[2]  R. Feld,et al.  Lateral epicondylitis of the elbow: US findings. , 2005, Radiology.

[3]  M. Åström Laser Doppler flowmetry in the assessment of tendon blood flow , 2000, Scandinavian journal of medicine & science in sports.

[4]  G. Bartsch,et al.  Sonoelastography of the prostate: comparison with systematic biopsy findings in 492 patients. , 2008, European journal of radiology.

[5]  Jess G. Snedeker,et al.  Elastography: modality-specific approaches, clinical applications, and research horizons , 2011, Skeletal Radiology.

[6]  F. Burke,et al.  Sonographic examination of lateral epicondylitis. , 2001, AJR. American journal of roentgenology.

[7]  S. Lambert,et al.  Ultrasound-guided autologous blood injection for tennis elbow , 2006, Skeletal Radiology.

[8]  B. Morrey,et al.  Microscopic histopathology of chronic refractory lateral epicondylitis , 1992, The American journal of sports medicine.

[9]  T. Matsumura,et al.  Breast disease: clinical application of US elastography for diagnosis. , 2006, Radiology.

[10]  H. Genant,et al.  MR imaging findings of lateral ulnar collateral ligament abnormalities in patients with lateral epicondylitis. , 1999, AJR. American journal of roentgenology.

[11]  H. Ermert,et al.  A time-efficient and accurate strain estimation concept for ultrasonic elastography using iterative phase zero estimation , 1999, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[12]  Stefano Bianchi,et al.  Ultrasound of the musculoskeletal system , 2007 .

[13]  H. Frey [Realtime elastography. A new ultrasound procedure for the reconstruction of tissue elasticity]. , 2003, Der Radiologe.

[14]  T. Miller,et al.  Comparison of sonography and MRI for diagnosing epicondylitis , 2002, Journal of clinical ultrasound : JCU.

[15]  L. Bisset,et al.  Diagnostic accuracy of power Doppler ultrasound in patients with chronic tennis elbow , 2008, British Journal of Sports Medicine.

[16]  Ann D King,et al.  Real-time qualitative ultrasound elastography of miscellaneous non-nodal neck masses: applications and limitations. , 2010, Ultrasound in medicine & biology.

[17]  R. Nirschl,et al.  Tennis elbow. The surgical treatment of lateral epicondylitis. , 1979, The Journal of bone and joint surgery. American volume.

[18]  Philippe Peetrons,et al.  Developments in musculoskeletal ultrasound and clinical applications , 2010, Skeletal Radiology.

[19]  K. Togashi,et al.  Thyroid gland tumor diagnosis at US elastography. , 2005, Radiology.

[20]  G A Gresham,et al.  Rotator cuff degeneration and lateral epicondylitis: a comparative histological study. , 1994, Annals of the rheumatic diseases.

[21]  A. Metzdorf,et al.  Achilles tendons: clinical relevance of neovascularization diagnosed with power Doppler US. , 2003, Radiology.

[22]  E. Drakonaki,et al.  Magnetic resonance imaging, ultrasound and real-time ultrasound elastography of the thigh muscles in congenital muscle dystrophy , 2010, Skeletal Radiology.

[23]  L. Nazarian,et al.  Sonographically Guided Percutaneous Needle Tenotomy for Treatment of Common Extensor Tendinosis in the Elbow , 2006, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[24]  F. Kallel,et al.  Tradeoffs in Elastographic Imaging , 2001, Ultrasonic imaging.

[25]  J. Ophir,et al.  Elastography: A Quantitative Method for Imaging the Elasticity of Biological Tissues , 1991, Ultrasonic imaging.

[26]  É. Cardinal,et al.  “Tenomalacia”: a new sonographic sign of tendinopathy? , 2008, European Radiology.