A case of compensated liver cirrhosis with hepatitis C virus of genotype 1b and high viral load in whom sustained virological response was achieved by 2-year administration of very low-dose recombinant interferon alpha-2b.

Approximately two million people are infected with hepatitis C virus (HCV) and it is a primary cause of hepatocellular carcinoma (HCC) in Japan [1]. Pegylated interferon (IFN) with ribavirin treatment is the standard therapy for chronic HCV infection nowadays, and the treatment achieves a sustained