Thoracic Paravertebral Block for Breast Surgery

Cosmetic and reconstructive breast augmentation is a frequently performed surgical procedure. Despite advances in medical treatment, surgical intervention is often associated with postoperative pain, nausea, and vomiting. Paravertebral nerve block (PVB) has the potential to offer long-lasting pain relief and fewer postoperative side effects when used for breast surgery. We compared thoracic PVB with general anesthesia for cosmetic breast surgery in a single-blinded, prospective, randomized study of 60 women scheduled for unilateral or bilateral breast augmentation or reconstruction. Patients were assigned (n = 30 per group) to receive a standardized general anesthetic (GA) or thoracic PVB (levels T1–7). Procedural data were collected, as well as verbal and visual analog pain and nausea scores. Verbal postoperative pain scores were significantly lower in the PVB group at 30 min (P = 0.0005), 1 h (P = 0.0001), and 24 h (P = 0.04) when compared with GA. Nausea was less severe in the PVB group at 24 h (P = 0.04), but not at 30 min or 1 h. We conclude that PVB is an alternative technique for cosmetic breast surgery that may offer superior pain relief and decreased nausea to GA alone. Implications Paravertebral nerve block has the potential to offer long-lasting pain relief and few postoperative side effects when used for breast surgery. We demonstrated that paravertebral nerve block, when compared with general anesthesia, is an alternative technique for breast surgery that may offer pain relief superior to general anesthesia alone.

[1]  H. Toyooka,et al.  Prophylactic antiemetic therapy with granisetron‐dexamethasone combination in women undergoing breast surgery , 1998, Acta anaesthesiologica Scandinavica.

[2]  J. Richardson,et al.  The Effect of Thoracic Paravertebral Blockade on Intercostal Somatosensory Evoked Potentials , 1998, Anesthesia and analgesia.

[3]  J. Chang,et al.  A review of breast cancer chemoprevention. , 1998, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[4]  H. Lyerly,et al.  Use of paravertebral block anesthesia in the surgical management of breast cancer: experience in 156 cases. , 1998, Annals of surgery.

[5]  M. Pozzi,et al.  Serum concentrations of bupivacaine during prolonged continuous paravertebral infusion in young infants. , 1997, British journal of anaesthesia.

[6]  S. Steele,et al.  Paravertebral block for breast cancer surgery , 1996, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[7]  E. Kalso,et al.  Pain and other symptoms after different treatment modalities of breast cancer. , 1995, Annals of oncology : official journal of the European Society for Medical Oncology.

[8]  E. Mariano,et al.  Atlas of Regional Anesthesia , 1994 .

[9]  A. Asbury,et al.  Studies in postoperative sequelae. Nausea and vomiting—still a problem , 1994, Anaesthesia.