ACUTE INFANTILE HEMORRHAGIC EDEMA : A CLINICAL PERSPECTIVE ( REPORT OF SEVEN CASES )

Acute infantile hemorrhagic edema (AIHE) is an uncommon cutaneous leukocytoclastic vasculitis characterized by large purpuric skin lesions, acral edema and fever. In spite of violent onset, spontaneous recovery without any sequelaes occurs within a few weeks. The causes of AIHE are unknown and there is no specific treatment. In this article, we have presented seven cases with AIHE admitted to our hospital between 2003-2006. We evaluated the effect of antihistaminic treatment on the course of the disease and we also reviewed the features of AIHE distinguishable from other purpuric diseases.

[1]  A. Taïeb,et al.  Acute Haemorrhagic Oedema of the Skin in Infancy , 2011 .

[2]  V. Di Lernia,et al.  Skin manifestations with Rotavirus infections , 2006, International journal of dermatology.

[3]  G. Lo Scocco,et al.  Infantile Acute Hemorrhagic Edema and Rotavirus Infection , 2004, Pediatric dermatology.

[4]  H. Çaksen,et al.  Report of Eight Infants with Acute Infantile Hemorrhagic Edema and Review of the Literature , 2002, The Journal of dermatology.

[5]  T. Millard,et al.  Acute infantile hemorrhagic oedema. , 1999, Journal of the American Academy of Dermatology.

[6]  F. Saulsbury,et al.  Acute hemorrhagic edema of infancy associated with pneumococcal bacteremia. , 1999, The Pediatric infectious disease journal.

[7]  C. Pignata,et al.  T Cell Activation Deficiency Associated with an Aberrant Pattern of Protein Tyrosine Phosphorylation after CD3 Perturbation in Down's Syndrome , 1998, Pediatric Research.

[8]  E. Cuadrado,et al.  Immune dysfunction in Down's syndrome: primary immune deficiency or early senescence of the immune system? , 1996, Clinical immunology and immunopathology.

[9]  F. Yalçınkaya,et al.  Infantile Acute Hemorrhagic Edema: A Variant of Leukocytoclastic Vasculitis , 1995, Pediatric dermatology.

[10]  K. Tınaztepe,et al.  Infantile acute hemorrhagic edema of the skin. , 1992, Journal of the American Academy of Dermatology.

[11]  A. Taïeb,et al.  Infantile acute hemorrhagic edema of the skin: study of ten cases. , 1991, Journal of the American Academy of Dermatology.

[12]  A. Tuncer,et al.  Acute hemorrhagic edema of infancy (AHEI)--a variant of Henoch-Schönlein purpura or a distinct clinical entity? , 1990, The Journal of allergy and clinical immunology.

[13]  M. Fabre,et al.  [Acute hemorrhagic edema in infants: role of adenoviruses? Apropos of a case]. , 1985, Pediatrie.

[14]  J. Melski,et al.  Cutaneous necrotizing venulitis. , 1979, Cutis.

[15]  H. O. Mackey Cutaneous Vascular Diseases , 1968 .

[16]  I. Snow PURPURA, URTICARIA AND ANGIONEUROTIC EDEMA OF THE HANDS AND FEET IN A NURSING BABY , 1913 .