Dementia with Lewy bodies: diagnosis and management

To summarize the clinical, pathological, imaging and treatment aspects of dementia with Lewy bodies (DLB).

[1]  Mrinalini Honavar,et al.  Lewy bodies and response to tacrine in Alzheimer's disease , 1994, The Lancet.

[2]  I G McKeith,et al.  The Clinician Assessment of Fluctuation and the One Day Fluctuation Assessment Scale. Two methods to assess fluctuating confusion in dementia. , 2000, The British journal of psychiatry : the journal of mental science.

[3]  Joseph E Parisi,et al.  Parkinson disease neuropathology: later-developing dementia and loss of the levodopa response. , 2002, Archives of neurology.

[4]  Robert H. Perry,et al.  Senile dementia of Lewy body type A clinically and neuropathologically distinct form of Lewy body dementia in the elderly , 1990, Journal of the Neurological Sciences.

[5]  S. Fahn Members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale , 1987 .

[6]  I. McKeith,et al.  Do differences in visuospatial ability between senile dementias of the Alzheimer and Lewy body types reflect differences solely in mnemonic function? , 1995, Journal of clinical and experimental neuropsychology.

[7]  I G McKeith,et al.  Report of the second dementia with Lewy body international workshop , 1999, Neurology.

[8]  C. Gottfries,et al.  The Clinical Efficacy of Citalopram in Treatment of Emotional Disturbances in Dementia Disorders a Nordic Multicentre Study , 1990, British Journal of Psychiatry.

[9]  M. Memo,et al.  Lewy-body dementia and responsiveness to cholinesterase inhibitors: a paradigm for heterogeneity of Alzheimer's disease? , 1996, Trends in pharmacological sciences.

[10]  E. Mori,et al.  Visuoperceptual impairment in dementia with Lewy bodies. , 2000, Archives of neurology.

[11]  A. Burns The burden of Alzheimer's disease. , 2000, The international journal of neuropsychopharmacology.

[12]  E. Perry,et al.  Operational criteria for senile dementia of Lewy body type (SDLT) , 1992, Psychological Medicine.

[13]  E. Perry,et al.  Psychiatric morbidity in dementia with Lewy bodies: a prospective clinical and neuropathological comparative study with Alzheimer's disease. , 1999, The American journal of psychiatry.

[14]  L. Thal,et al.  Cognitive decline is faster in Lewy body variant than in Alzheimer's disease , 1998, Neurology.

[15]  R. Crowther,et al.  α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies , 1998 .

[16]  M. Mega,et al.  The Neuropsychiatric Inventory , 1994, Neurology.

[17]  E. Perry,et al.  Influence of apolipoprotein E genotype on senile dementia of the Alzheimer and Lewy body types. Significance for etiological theories of Alzheimer's disease. , 1994, The American journal of pathology.

[18]  P. Lantos,et al.  Validity of current clinical criteria for Alzheimer's disease, vascular dementia and dementia with Lewy bodies , 1999, British Journal of Psychiatry.

[19]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[20]  Jellinger Ka Structural basis of dementia in neurodegenerative disorders , 1996 .

[21]  I. McKeith,et al.  Senile dementia of lewy body type—a review of clinical and pathological features: Implications for treatment , 1995 .

[22]  M. L. Schmidt,et al.  α-Synuclein in Lewy bodies , 1997, Nature.

[23]  G. E. Smith,et al.  REM sleep behavior disorder and degenerative dementia , 1998, Neurology.

[24]  K. Davis,et al.  Neocortical cholinergic activities differentiate Lewy body dementia from classical Alzheimer's disease. , 1994, Neuroreport.

[25]  L. R. Hill,et al.  The apolipoprotein E allele epsi;4 is overrepresented in patients with the Lewy body variant of Alzheimer's disease , 1994, Neurology.

[26]  H. Ross,et al.  A 10-year study of the incidence of and factors predicting dementia in Parkinson’s disease , 2000, Neurology.

[27]  E. Perry,et al.  Neuroleptic sensitivity in patients with senile dementia of Lewy body type. , 1992, BMJ.

[28]  A. Lees,et al.  A clinicopathologic study of 100 cases of Parkinson's disease. , 1993, Archives of neurology.

[29]  I. McKeith,et al.  The Prevalence, Assessment and Associations of Falls in Dementia with Lewy Bodies and Alzheimer’s Disease , 1999, Dementia and Geriatric Cognitive Disorders.

[30]  B. Hyman,et al.  Dementia with Lewy Bodies , 1998, Journal of the American Geriatrics Society.

[31]  K. Chaudhuri,et al.  A study of excessive daytime sleepiness and its clinical significance in three groups of Parkinson's disease patients taking pramipexole, cabergoline and levodopa mono and combination therapy , 2001, Journal of Neural Transmission.

[32]  R. Hauser,et al.  Pramipexole‐induced somnolence and episodes of daytime sleep , 2000, Movement disorders : official journal of the Movement Disorder Society.

[33]  M. Drazner,et al.  Clinical and pathological aspects of parkinsonism in Alzheimer's disease. A role for extranigral factors? , 1989, Archives of neurology.

[34]  I. McKeith,et al.  Neuroleptic sensitivity to risperidone in Lewy body dementia , 1995, The Lancet.

[35]  K. Wesnes,et al.  Quantification and Characterisation of Fluctuating Cognition in Dementia with Lewy Bodies and Alzheimer’s Disease , 2000, Dementia and Geriatric Cognitive Disorders.

[36]  R. Teunisse,et al.  Visual hallucinations in psychologically normal people: Charles Bonnet's syndrome , 1996, The Lancet.

[37]  H. Querfurth,et al.  Acetylcholinesterase Inhibition in Dementia with Lewy Bodies: Results of a Prospective Pilot Trial , 2000, Dementia and Geriatric Cognitive Disorders.

[38]  E. Perry,et al.  Dementia with Lewy Bodies: Altered consciousness and transmitter signalling in Lewy body dementia , 1996 .

[39]  I. Ferrier,et al.  An evaluation of the predictive validity and inter‐rater reliability of clinical diagnostic criteria for senile dementia of Lewy body type , 1994, Neurology.

[40]  K. Marder,et al.  A population-based investigation of Parkinson's disease with and without dementia. Relationship to age and gender. , 1992, Archives of neurology.

[41]  Ian G. McKeith,et al.  Comparison of Extrapyramidal Signs in Dementia With Lewy Bodies and Parkinson's Disease , 2001 .

[42]  J D Fenwick,et al.  Occipital hypoperfusion on SPECT in dementia with Lewy bodies but not AD , 2001, Neurology.

[43]  G. Wilcock,et al.  Tacrine for senile dementia of Alzheimer's or Lewy body type , 1994, The Lancet.

[44]  C. Tanner,et al.  Early dopaminergic drug-induced hallucinations in parkinsonian patients , 1998, Neurology.

[45]  M. Sambrook,et al.  Motor and cognitive function in Lewy body dementia: comparison with Alzheimer's and Parkinson's diseases. , 1997, Journal of neurology, neurosurgery, and psychiatry.

[46]  G. Glosser,et al.  Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson’s disease , 2000, Neurology.

[47]  P. Scheltens,et al.  White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer’s disease, vascular dementia, and normal aging , 1999, Journal of neurology, neurosurgery, and psychiatry.

[48]  F. Pasquier,et al.  Tacrine efficacy in Lewy body dementia , 1998, International journal of geriatric psychiatry.

[49]  K. Kosaka,et al.  Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB) , 1996, Neurology.

[50]  C. Hofstetter,et al.  Dementia with Lewy Bodies Versus Pure Alzheimer Disease: Differences in Cognition, Neuropathology, Cholinergic Dysfunction, and Synapse Density , 1997, Journal of neuropathology and experimental neurology.

[51]  A. Swann,et al.  Prospective validation of Consensus criteria for the diagnosis of dementia with Lewy bodies , 2000, Neurology.

[52]  I G McKeith,et al.  Medial temporal lobe atrophy on MRI in dementia with Lewy bodies , 1999, Neurology.

[53]  Murat Emre,et al.  Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study , 2000, The Lancet.

[54]  J. Cummings,et al.  Benefit-Risk Considerations in the Treatment of Dementia with Lewy Bodies , 2002, Drug safety.

[55]  D. Salmon,et al.  Dementia with Lewy Bodies: Neuropsychological aspects of Lewy body dementia , 1996 .

[56]  L. Thal,et al.  The Lewy body variant of Alzheimer's disease , 1990, Neurology.

[57]  P. Jansen,et al.  Sodium valproate in the treatment of aggressive behavior in patients with dementia—a randomized placebo controlled clinical trial , 2002, International journal of geriatric psychiatry.

[58]  M. Hutchinson,et al.  Cholinesterase inhibition in Parkinson's disease. , 1996, Journal of neurology, neurosurgery, and psychiatry.

[59]  S. Fahn,et al.  Comparison of extrapyramidal features in 31 pathologically confirmed cases of diffuse lewy body disease and 34 pathologically confirmed cases of parkinson's disease , 1997, Neurology.

[60]  E. Mori,et al.  Cognitive loss in dementia with Lewy bodies and Alzheimer disease. , 1998, Archives of neurology.

[61]  E. Spina,et al.  Clinically Significant Drug Interactions with Antidepressants in the Elderly , 2002, Drugs & aging.

[62]  R. Schiffer,et al.  A review of Lewy body disease, an emerging concept of cortical dementia. , 1998, The Journal of neuropsychiatry and clinical neurosciences.

[63]  J. Hodges,et al.  Semantic memory is impaired in both dementia with Lewy bodies and dementia of Alzheimer's type: a comparative neuropsychological study and literature review , 2001, Journal of neurology, neurosurgery, and psychiatry.

[64]  G. Halliday,et al.  Visual hallucinations in Lewy body disease relate to Lewy bodies in the temporal lobe. , 2002, Brain : a journal of neurology.

[65]  A. Burns,et al.  Neuroleptic sensitivity in dementia with cortical Lewy bodies. , 1992, BMJ.

[66]  I. McKeith,et al.  A Detailed Phenomenological Comparison of Complex Visual Hallucinations in Dementia With Lewy Bodies and Alzheimer's Disease , 1997, International Psychogeriatrics.

[67]  I. McKeith,et al.  Dementia with Lewy Bodies: Noncognitive symptoms in Lewy body dementia , 1996 .

[68]  I. McKeith,et al.  The progression of cognitive impairment in dementia with Lewy bodies, vascular dementia and Alzheimer's disease , 2001, International journal of geriatric psychiatry.

[69]  I G McKeith,et al.  Quantifying fluctuation in dementia with Lewy bodies, Alzheimer’s disease, and vascular dementia , 2000, Neurology.

[70]  P. Lantos,et al.  Pathology of familial Alzheimer's disease with Lewy bodies. , 1997, Journal of neural transmission. Supplementum.

[71]  E. Masliah,et al.  Plaque‐Only Alzheimer Disease is Usually the Lewy Body Variant, and Vice Versa , 1993, Journal of neuropathology and experimental neurology.

[72]  Atta Ae Letter: Perinatal mortality. , 1974 .

[73]  Candace S. Brown,et al.  Atypical Antipsychotics Part I: Pharmacology, Pharmacokinetics, and Efficacy , 1999, The Annals of pharmacotherapy.

[74]  K. Kameyama,et al.  Alterations of muscarinic acetylcholine receptor subtypes in diffuse Lewy body disease: relation to Alzheimer’s disease , 1999, Journal of neurology, neurosurgery, and psychiatry.

[75]  Z Walker,et al.  Long-Term Use of Rivastigmine in Patients With Dementia With Lewy Bodies: An Open-Label Trial , 2001, International Psychogeriatrics.

[76]  R. Godwin-Austen,et al.  Diffuse Lewy body disease: clinical features in 15 cases. , 1989, Journal of neurology, neurosurgery, and psychiatry.

[77]  E. Byrne,et al.  Dementia With Lewy Bodies Treated With Rivastigmine: Effects on Cognition, Neuropsychiatric Symptoms, and Sleep , 2001, International Psychogeriatrics.

[78]  Z Walker,et al.  Differentiation of dementia with Lewy bodies from Alzheimer's disease using a dopaminergic presynaptic ligand , 2002, Journal of neurology, neurosurgery, and psychiatry.

[79]  J. Rabey,et al.  The beneficial effect of cholinesterase inhibitors on patients suffering from Parkinson's disease and dementia , 2000, Neurobiology of Aging.

[80]  C. Katona,et al.  Three years survival in patients with a clinical diagnosis of dementia with Lewy bodies , 2000, International journal of geriatric psychiatry.

[81]  N. Herrmann,et al.  Donepezil for behavioural disorders associated with Lewy bodies: a case series , 2000, International journal of geriatric psychiatry.

[82]  E. Perry,et al.  Senile dementia of Lewy body type and Alzheimer type are biochemically distinct in terms of paired helical filaments and hyperphosphorylated tau protein. , 1994, Dementia.

[83]  I. McKeith,et al.  Olanzapine in dementia with Lewy bodies: a clinical study , 1999, International journal of geriatric psychiatry.

[84]  F. Lewy Paralysis agitans. I. Pathologische Anatomie , 1912 .

[85]  S. Tsuji,et al.  Autosomal dominant diffuse Lewy body disease , 1998, Acta Neuropathologica.

[86]  H. Arai,et al.  18F-fluorodopa PET study of striatal dopamine uptake in the diagnosis of dementia with Lewy bodies , 2000, Neurology.

[87]  R. Godwin-Austen,et al.  Diffuse Lewy body disease: correlative neuropathology using anti-ubiquitin immunocytochemistry. , 1989, Journal of neurology, neurosurgery, and psychiatry.

[88]  D. Neary,et al.  Qualitative performance characteristics differentiate dementia with Lewy bodies and Alzheimer's disease , 2002, Journal of neurology, neurosurgery, and psychiatry.

[89]  Jeffrey L. Cummings,et al.  Dementia with Lewy bodies , 1996, Neurology.

[90]  I G McKeith,et al.  MRI volumetric study of dementia with Lewy bodies , 2000, Neurology.

[91]  D. Aarsland,et al.  Donepezil for cognitive impairment in Parkinson's disease: a randomised controlled study , 2002, Journal of neurology, neurosurgery, and psychiatry.

[92]  D. Aarsland,et al.  Risk of dementia in Parkinson’s disease , 2001, Neurology.

[93]  C. Marsden,et al.  Recent Developments in Parkinson's Disease , 1986 .

[94]  V. Lerner,et al.  Successful Use of Donepezil for the Treatment of Psychotic Symptoms in Patients With Parkinson's Disease , 2002, Clinical neuropharmacology.

[95]  E. Perry,et al.  Tautological tangles in neuropathologic criteria for dementias associated with Lewy bodies , 1996 .

[96]  W. Burke,et al.  Neuroleptic sensitivity to clozapine in dementia with Lewy bodies. , 1998, The Journal of neuropsychiatry and clinical neurosciences.

[97]  K. Rockwood,et al.  Donepezil for Treatment of Dementia With Lewy Bodies: A Case Series of Nine Patients , 1998, International Psychogeriatrics.

[98]  E. Perry,et al.  Evidence of a Monoaminergic‐Cholinergic Imbalance Related to Visual Hallucinations in Lewy Body Dementia , 1990, Journal of neurochemistry.

[99]  D. Collier,et al.  DRD2 Ser311/Cys311 polymorphism in schizophrenia , 1994, The Lancet.

[100]  I. McKeith,et al.  Spectrum of Parkinson's disease, Parkinson's dementia, and Lewy body dementia. , 2000, Neurologic clinics.

[101]  E. Perry,et al.  CLINICALLY AND NEUROPATHOLOGICALLY DISTINCT FORM OF DEMENTIA IN THE ELDERLY , 1989, The Lancet.

[102]  E. Perry,et al.  Rivastigmine in the treatment of dementia with Lewy bodies: preliminary findings from an open trial , 2000, International journal of geriatric psychiatry.

[103]  I G McKeith,et al.  Rivastigmine in the treatment of parkinsonian psychosis and cognitive impairment: Preliminary findings from an open trial , 2001, Movement disorders : official journal of the Movement Disorder Society.

[104]  Y. Agid,et al.  Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trialCommentary: Another piece of the Alzheimer's jigsaw , 1999 .

[105]  D. Salmon,et al.  Rapidly progressive dementia in a patient with the Lewy body variant of Alzheimer's disease , 1991, Neurology.

[106]  Douglas Galasko,et al.  Better cognitive and psychopathologic response to donepezil in patients prospectively diagnosed as dementia with Lewy bodies: a preliminary study , 2000, International journal of geriatric psychiatry.

[107]  K. Marder,et al.  Neuropsychological characteristics of preclinical dementia in Parkinson's disease , 1995, Neurology.

[108]  C. Ballard,et al.  Cognitive decline in patients with Alzheimer's disease, vascular dementia and senile dementia of Lewy body type. , 1996, Age and ageing.

[109]  I G McKeith,et al.  Striatal dopaminergic markers in dementia with Lewy bodies, Alzheimer's and Parkinson's diseases: rostrocaudal distribution. , 1999, Brain : a journal of neurology.

[110]  R. Mayer,et al.  Dementia with Lewy Bodies: Pathological significance of Lewy bodies in dementia , 1996 .