Implementation and Validation of ECG-Derived Respiration with QRS Characteristics

This study presents a method for reconstructing respiration signals from ECG tracings based on average electrical-cardiac-axis theory with heart rate variability. The algorithm is simplified to use QRS characteristic points and subsequent spectrum analysis. The experiments were conducted on eight healthy patients during rest with spontaneous (voluntarily) and paced breathings. Five QRS characteristic series are constructed, and the corresponding electrocardiography (ECG)-derived respiration (EDR) is compared with measured data. The experiment results show the R-Q-S series-derived respiration exhibited superior correlation with the original respiration from the perspective of breathing frequency.

[1]  J. Nyboer,et al.  Electrical Impedance Plethysmography: A Physical and Physiologic Approach to Peripheral Vascular Study , 1950, Circulation.

[2]  Massimo Ferri,et al.  Respiratory signal derived from eight-lead ECG , 1998, Computers in Cardiology 1998. Vol. 25 (Cat. No.98CH36292).

[3]  S. Reisman,et al.  Respiration derived from the electrocardiogram: a quantitative comparison of three different methods , 1996, Proceedings of the IEEE 22nd Annual Northeast Bioengineering Conference.

[4]  Chih-Yu Hsu,et al.  Discrete Wavelet Transform Applied on Personal Identity Verification with ECG Signal , 2009, Int. J. Wavelets Multiresolution Inf. Process..

[5]  O P Mathew,et al.  Changes in transthoracic electrical impedance at high altitude. , 1977, British heart journal.

[6]  T. Findley,et al.  Derivation of respiration from electrocardiogram during heart rate variability studies , 1994, Computers in Cardiology 1994.

[7]  L.E. Baker Applications of the impedance technique to the respiratory system , 1989, IEEE Engineering in Medicine and Biology Magazine.

[8]  Eran Toledo,et al.  Cardiorespiratory synchronization: is it a real phenomenon? , 1999, Computers in Cardiology 1999. Vol.26 (Cat. No.99CH37004).

[9]  Khosrow Behbehani,et al.  Reconstruction of respiratory patterns from electrocardiographic signals , 1998, Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269).

[10]  D. T. Kaplan,et al.  Nonlinear interactions between respiration and heart rate: classical physiology or entrained nonlinear oscillators , 1988, Proceedings. Computers in Cardiology 1988.

[11]  R. Rosenfeld Nature , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[12]  Chun-Liang Lin,et al.  Personalized information encryption using ECG signals with chaotic functions , 2012, Inf. Sci..

[13]  C. Marchesi,et al.  Circadian dynamics of respiratory parameters from ambulatory monitoring , 1994, Computers in Cardiology 1994.

[14]  Francesco Pinciroli,et al.  Processing electrocardiograms towards respiratory signals , 1988, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[15]  D. Eckberg,et al.  Important influence of respiration on human R-R interval power spectra is largely ignored. , 1993, Journal of applied physiology.

[16]  George B. Moody,et al.  Derivation of Respiratory Signals from Multi-lead ECGs , 2008 .

[17]  C. Lamberti,et al.  Validation of an ECG-derived respiration monitoring method , 2003, Computers in Cardiology, 2003.

[18]  G. Moody,et al.  Clinical Validation of the ECG-Derived Respiration (EDR) Technique , 2008 .

[19]  L. Geddes Intraoesophageal monitoring of the electrocardiogram and respiration in anaesthetised animals , 2006, Medical and Biological Engineering and Computing.