Experience of Intraoperative Recurrent Laryngeal Nerve monitoring in a Single Center-normative Recurrent Laryngeal Nerve Electromyographic Data

Introduction: Injury to the recurrent laryngeal nerve (RLN) remains a significant morbidity during thyroid and parathyroid surgery. The aim of this study is to elucidate normative RLN electromyographic (EMG) parameters. Materials and methods: This is a retrospective cohort study of patients who underwent Intraoperative neuromonitoring during thyroid and parathyroid surgery from February 2014 to March 2015. The inomed C2 NerveMonitor was used. We recorded the stimulation current, amplitude, and latency of the RLN before and after nerve dissection. We also observed the number of patients who had hoarse voice after surgery. Results: A total of 46 patients (14 male, 32 female) averaging 51 years old in age (20−77 years) were analyzed. The most commonly performed surgical procedure was total thyroidectomy (53.2%). The median stimulation current for both the right and left RLN was 0.500 mA. The median amplitude for the left RLN was 1.060 mV and greater than that for the right RLN (0.930 mV) (p = 0.30). The median latency for the right RLN and left RLN was 2.40 ms with no difference between the sides. (p = 0.58). Post dissection, the right RLN amplitude remained identical whereasthe left RLN amplitude decreased. Latencies of both RLNs decreased although the difference was not significant. Nature of pathology and site of surgery did not influence RLN latency and amplitude. No patients had hoarse voice. Conclusion: This study highlights the normative EMG parameters for bilateral RLN nerve stimulation in an Asian population. No significant difference was noted in both preand postdissection RLN EMG parameters.

[1]  H. Lee,et al.  Traction injury of the recurrent laryngeal nerve: Results of continuous intraoperative neuromonitoring in a swine model , 2016, Head & neck.

[2]  I. Ioniță,et al.  Intraoperative Monitoring of the Recurrent Laryngeal Nerve During Thyroidectomy , 2015 .

[3]  P. Cuvelier,et al.  Value of intra-operative neuromonitoring of the recurrent laryngeal nerve in total thyroidectomy for benign goitre , 2015, The Journal of Laryngology & Otology.

[4]  L. Orloff,et al.  Stimulation threshold greatly affects the predictive value of intraoperative nerve monitoring , 2015, The Laryngoscope.

[5]  J. Schreinemakers,et al.  Thyroid Surgery and the Usefulness of Intraoperative Neuromonitoring, a Single Center Study , 2015, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

[6]  G. Dionigi,et al.  Evidence-based Analysis on The Clinical Impact of Intraoperative Neuromonitoring in Thyroid Surgery: State of the Art and Future Perspectives. , 2014, Surgical technology international.

[7]  G. Dionigi,et al.  Intraoperative neuromonitoring for the early detection and prevention of RLN traction injury in thyroid surgery: a porcine model. , 2014, Surgery.

[8]  M. Barczyński,et al.  [Evaluation of implementation phase of intraoperative neural monitoring of the recurrent laryngeal nerves in thyroid surgery in a district hospital]. , 2014, Przeglad lekarski.

[9]  G. Randolph,et al.  Intraoperative neural monitoring in thyroid cancer surgery , 2014, Langenbeck's Archives of Surgery.

[10]  G. Randolph,et al.  Intraoperative monitoring: Normative range associated with normal postoperative glottic function , 2013, The Laryngoscope.

[11]  J. Pardal-Refoyo Usefulness of neuromonitoring in thyroid surgery. , 2012, Acta otorrinolaringologica espanola.

[12]  D. Zurakowski,et al.  Recurrent Laryngeal Nerve Monitoring during Thyroid Surgery , 2012, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[13]  A. Bozorg Grayeli,et al.  Intraoperative laryngeal nerve monitoring during thyroidectomy and parathyroidectomy: A prospective study. , 2012, European annals of otorhinolaryngology, head and neck diseases.

[14]  T. Sloan,et al.  Electrophysiologic recurrent laryngeal nerve monitoring during thyroid and parathyroid surgery: International standards guideline statement , 2011, The Laryngoscope.

[15]  C. Sekulla,et al.  What are normal quantitative parameters of intraoperative neuromonitoring (IONM) in thyroid surgery? , 2010, Langenbeck's Archives of Surgery.

[16]  U. Caliceti,et al.  The value of neurostimulation and intraoperative nerve monitoring of inferior laryngeal nerve in thyroid surgery , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[17]  H. Mårtensson,et al.  Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients , 2008, Langenbeck's Archives of Surgery.

[18]  M. Barczyński,et al.  [Value of the intraoperative neuromonitoring in surgery for thyroid cancer in identification and prognosis of function of the recurrent laryngeal nerves]. , 2006, Endokrynologia Polska.

[19]  M. Freissmuth,et al.  Neuromonitoring in Thyroid Surgery: Prospective Evaluation of Intraoperative Electrophysiological Responses for the Prediction of Recurrent Laryngeal Nerve Injury , 2004, Annals of Surgery.

[20]  D. Lydiatt Medical malpractice and the thyroid gland , 2003, Head & neck.

[21]  S. Kwok,et al.  Outcomes and complications of thyroid surgery: retrospective study. , 2001, Hong Kong medical journal = Xianggang yi xue za zhi.

[22]  K. Kern Medicolegal analysis of errors in diagnosis and treatment of surgical endocrine disease. , 1993, Surgery.

[23]  Eaton Surgery of the thyroid gland , 1903, British medical journal.