Research priorities relevant to development or updating of nano-relevant regulations and guidelines

The use of a diverse array of NM in wide array of consumer, industrial and medical applications has led to an increased interest in improving our understanding of issues pertaining to their safe use. The European Commission has funded many projects during the Framework programme 7 which initially set out to identify whether there were significant safety issues relating to nanomaterials (e.g. NANOIMMUNE, NANOGENOTOX, ENPRA, MARINA, NANOSOLUTIONS, MARINA, NanoTEST). Based upon the evidence generated by these studies, EU projects have now moved on to develop strategies for risk assessment and decision making (e.g. MARINA, SUN, GUIDENANO, NANOSOLUTIONS) and to identify whether nanomaterials are adequately regulated by current European legislation (e.g. NANoREG and RIPoN). These activities are being further enhanced in Horizon 2020 with the funding of PROSAFE, NANoREG II and other new projects.

[1]  Hugh J. Byrne,et al.  Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10 , 2013, Nanotoxicology.

[2]  Laura Hodson,et al.  Harmonization of measurement strategies for exposure to manufactured nano-objects; report of a workshop. , 2012, The Annals of occupational hygiene.

[3]  M Methner,et al.  Nanoparticle Emission Assessment Technique (NEAT) for the Identification and Measurement of Potential Inhalation Exposure to Engineered Nanomaterials—Part A , 2010, Journal of occupational and environmental hygiene.

[4]  Kimberly F. Sellers,et al.  Grouping nanomaterials : A strategy towards grouping and read-across , 2015 .

[5]  Usage of (eco)toxicological data for bridging data gaps between and grouping of nanoforms of the same substance , 2016 .

[6]  M Methner,et al.  Nanoparticle Emission Assessment Technique (NEAT) for the Identification and Measurement of Potential Inhalation Exposure to Engineered Nanomaterials—Part B: Results from 12 Field Studies , 2010, Journal of occupational and environmental hygiene.

[7]  Antonio Marcomini,et al.  Grouping and Read-Across Approaches for Risk Assessment of Nanomaterials , 2015, International journal of environmental research and public health.

[8]  Lang Tran,et al.  The biologically effective dose in inhalation nanotoxicology. , 2013, Accounts of chemical research.

[9]  U. Tillmann,et al.  A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data. , 1997, Regulatory toxicology and pharmacology : RTP.