ANTIMICROBIAL DRUG USE IN DERMATOLOGY IN A TEACHING HOSPITAL IN WESTERN NEPAL

Medical audit is supposed to oversee, monitor and analyse standards of medical treatment at all levels of the healthcare delivery system. This study was undertaken to monitor the prescribing of antimicrobial drugs for patients seeking treatment in the dermatology outpatient department of the Manipal Teaching Hospital in Nepal. A total of 292 dermatology prescriptions of patients attending the dermatology OPD were collected between July 2000 and June 2001. Prescriptions for antimicrobial agents were separated from the total prescriptions collected, and evaluated. There were more female patients (58.2%) than male (41.8%) in our study; most were in the 21–40 year age group. The commonest cutaneous infections were acne (15.8%) followed by fungal infections (14.8%). Of the 292 prescriptions audited, 149 contained antimicrobial agents, constituting 36% of the total number of drugs prescribed. Of 256 antimicrobials prescribed, 63% were topical and 37% systemic; 5% were generic, 29% were from the essential drug list of Nepal, and 15% were fixed‐dose combinations. Most of the patients received one or two antimicrobials, 50% of which were antibacterials and 40% antifungals. Though the selection of antimicrobial drugs used in dermatology was largely rational, anomalies were observed, and these issues were discussed with clinicians in relation to various aspects of drug use. The results indicate there is scope for improving prescribing habits. A periodic audit of drug prescribing is desirable in rationalising prescribing practice.

[1]  R. Summerbell,et al.  Once weekly fluconazole is effective in children in the treatment of tinea capitis: a prospective, multicentre study , 2000, The British journal of dermatology.

[2]  D. Shewade,et al.  Auditing of prescriptions in a government teaching hospital and four retail medical stores in Pondicherry , 1998 .

[3]  D. Shewade,et al.  Training medical professionals on the concepts of essential drugs and rational drug use. , 1994, British journal of clinical pharmacology.

[4]  S. Levy Confronting multidrug resistance. A role for each of us. , 1993, JAMA.

[5]  S. Sharma,et al.  Topical corticosteroids usage in dermatology. , 1991, International journal of clinical pharmacology, therapy, and toxicology.

[6]  Economic prescribing , 1991, Drug and therapeutics bulletin.

[7]  G. Tomson,et al.  Drug prescribing patterns: a study of four institutions in Sri Lanka. , 1988, International journal of clinical pharmacology, therapy and toxicology.

[8]  R. Glass,et al.  Antibiotic use in a rural community in Bangladesh. , 1982, International journal of epidemiology.

[9]  C. Victora,et al.  Drug Usage in Southern Brazilian Hospitals , 1982, Tropical doctor.

[10]  K S Warren,et al.  Selective primary health care: an interim strategy for disease control in developing countries. , 1979, The New England journal of medicine.

[11]  G. Dunea Letter from ... Chicago. Shopping-bag syndrome. , 1977, British medical journal.

[12]  K. Krishnaswamy,et al.  A drug survey — Precepts and practices , 2004, European Journal of Clinical Pharmacology.

[13]  F. Gross,et al.  Drug utilization — Theory and practice the present situation in the Federal Republic of Germany , 2004, European Journal of Clinical Pharmacology.

[14]  M. Joshi RATIONAL USE OF ANTIBIOTICS IN HOSPITALS , 2003 .

[15]  P. Morel,et al.  [Dermatologic consultation in a precarious situation: a prospective medical and social study at the Hôpital Saint-Louis in Paris]. , 1999, Annales de dermatologie et de vénéréologie.

[16]  L. Parish Newer concepts in antimicrobial therapy. , 1999, Advances in experimental medicine and biology.

[17]  R. C. Pandey,et al.  EVALUATION OF PRESCRIBING PATTERN OF DOCTORS FOR RATIONAL DRUG THERAPY , 1998 .

[18]  R. Summers Drug utilization in internal medicine wards at a teaching hospital serving a developing community. , 1985, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.