iNOS dependent and independent phases of lymph node expansion in mice with TNF-induced inflammatory-erosive arthritis

[1]  E. Schwarz,et al.  Selective Sexual Dimorphisms in Musculoskeletal and Cardiopulmonary Pathologic Manifestations and Mortality Incidence in the Tumor Necrosis Factor–Transgenic Mouse Model of Rheumatoid Arthritis , 2019, Arthritis & rheumatology.

[2]  Eelco F. J. Meijer,et al.  Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction , 2018, Science Translational Medicine.

[3]  E. Schwarz,et al.  Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis , 2018, Nature Reviews Rheumatology.

[4]  E. Schwarz,et al.  Longitudinal micro-CT as an outcome measure of interstitial lung disease in TNF-transgenic mice , 2018, PloS one.

[5]  E. Schwarz,et al.  Brief Report: Treatment of Tumor Necrosis Factor–Transgenic Mice With Anti–Tumor Necrosis Factor Restores Lymphatic Contractions, Repairs Lymphatic Vessels, and May Increase Monocyte/Macrophage Egress , 2017, Arthritis & rheumatology.

[6]  Jorge A. Castorena‐Gonzalez,et al.  Lymphatic pumping: mechanics, mechanisms and malfunction , 2016, The Journal of physiology.

[7]  E. Schwarz,et al.  Lymphatic imaging to assess rheumatoid flare: mechanistic insights and biomarker potential , 2016, Arthritis Research & Therapy.

[8]  H. Perlman,et al.  The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases , 2016, Nature Reviews Rheumatology.

[9]  Hua Tang,et al.  Dendritic cell-derived nitric oxide inhibits the differentiation of effector dendritic cells , 2016, Oncotarget.

[10]  E. Schwarz,et al.  Lymphatic endothelial cells efferent to inflamed joints produce iNOS and inhibit lymphatic vessel contraction and drainage in TNF-induced arthritis in mice , 2016, Arthritis Research & Therapy.

[11]  M. A. Spadella,et al.  Collagen‐induced arthritis increases inducible nitric oxide synthase not only in aorta but also in the cardiac and renal microcirculation of mice , 2016, Clinical and experimental immunology.

[12]  S. Kim,et al.  Arginase 1 is a negative regulator of osteoclast differentiation , 2016, Amino Acids.

[13]  D. Jowhar,et al.  Inhibition of Inflammation and iNOS Improves Lymphatic Function in Obesity , 2016, Scientific Reports.

[14]  E. Schwarz,et al.  TNF signals are dispensable for the generation of CD23+ CD21/35-high CD1d-high B cells in inflamed lymph nodes. , 2015, Cellular immunology.

[15]  S. Chakraborty,et al.  Emerging trends in the pathophysiology of lymphatic contractile function. , 2015, Seminars in cell & developmental biology.

[16]  J. Li,et al.  The role of the lymphatic system in inflammatory-erosive arthritis. , 2015, Seminars in cell & developmental biology.

[17]  D. Mooney,et al.  The CLEC-2–podoplanin axis controls fibroblastic reticular cell contractility and lymph node microarchitecture , 2014, Nature Immunology.

[18]  E. Schwarz,et al.  In vivo quantification of lymph viscosity and pressure in lymphatic vessels and draining lymph nodes of arthritic joints in mice , 2014, The Journal of physiology.

[19]  E. Schwarz,et al.  Power Doppler Ultrasound Phenotyping of Expanding versus Collapsed Popliteal Lymph Nodes in Murine Inflammatory Arthritis , 2013, PloS one.

[20]  P. Taylor,et al.  Ultrasonographic measures of synovitis in an early phase clinical trial: a double-blind, randomised, placebo and comparator controlled phase IIa trial of GW274150 (a selective inducible nitric oxide synthase inhibitor) in rheumatoid arthritis. , 2012, Clinical and experimental rheumatology.

[21]  Dai Fukumura,et al.  Impaired lymphatic contraction associated with immunosuppression , 2011, Proceedings of the National Academy of Sciences.

[22]  J. Li,et al.  CD23+/CD21hi B-cell translocation and ipsilateral lymph node collapse is associated with asymmetric arthritic flare in TNF-Tg mice , 2011, Arthritis research & therapy.

[23]  J. Li,et al.  Expanded CD23+/CD21hi B Cells in Inflamed Lymph Nodes Are Associated with the Onset of Inflammatory-Erosive Arthritis in TNF-Transgenic Mice and Are Targets of Anti-CD20 Therapy , 2010, The Journal of Immunology.

[24]  Carlos Zaragoza,et al.  Recent Insights into the Implication of Nitric Oxide in Osteoblast Differentiation and Proliferation during Bone Development , 2010, TheScientificWorldJournal.

[25]  H. Perlman,et al.  The synovial lining micromass system: toward rheumatoid arthritis in a dish? , 2010, Arthritis and rheumatism.

[26]  E. Schwarz,et al.  Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis. , 2009, Arthritis and rheumatism.

[27]  M. J. Ashby,et al.  Inducible nitric oxide synthase activity is increased in patients with rheumatoid arthritis and contributes to endothelial dysfunction. , 2008, International journal of cardiology.

[28]  M. O. Papuga,et al.  Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography. , 2007, Arthritis and rheumatism.

[29]  P. Collin‐Osdoby,et al.  RANKL Stimulates Inducible Nitric-oxide Synthase Expression and Nitric Oxide Production in Developing Osteoclasts , 2006, Journal of Biological Chemistry.

[30]  E. Schwarz,et al.  RANK Signaling Is Not Required for TNFα‐Mediated Increase in CD11bhi Osteoclast Precursors but Is Essential for Mature Osteoclast Formation in TNFα‐Mediated Inflammatory Arthritis , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[31]  E. Schwarz,et al.  The TNF-α transgenic mouse model of inflammatory arthritis , 2003, Springer Seminars in Immunopathology.

[32]  G. Firestein.  Evolving concepts of rheumatoid arthritis , 2003, Nature.

[33]  P. Hutchinson,et al.  Suppression of Adjuvant Arthritis and Synovial Macrophage Inducible Nitric Oxide by N-iminoethyl-L-Ornithine, A Nitric Oxide Synthase Inhibitor , 1997, Inflammation.

[34]  S. Wahl,et al.  Suppression of arthritis by an inhibitor of nitric oxide synthase , 1993, The Journal of experimental medicine.

[35]  J. Li,et al.  Efficacy of B cell depletion therapy for murine joint arthritis flare is associated with increased lymphatic flow. , 2013, Arthritis and rheumatism.

[36]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[37]  G. Kollias,et al.  Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis. , 1995, Journal of inflammation.