The role of the obstetrician in the prevention of cervical cancer.

FOR the past ten years there has been an increasing interest in the concept that invasive carcinoma of the cervix is preceded by an in situ stage that has all the morphologic properties of cancer except invasion of the stroma. Furthermore, there is evidence that carcinoma in situ does not arise de novo, but is preceded by recognizable cytologic and morphologic changes variously described as epithelial anaplasia, dysplasia, atypia or equivocal lesions.1 2 3 4 The immense importance of this concept lies in the implication that if these changes are progressive then their eradication constitutes a method of prevention of frank invasive cancer. . . .

[1]  R. Greene,et al.  Follow-up on cervical epithelial abnormalities. , 1957, American journal of obstetrics and gynecology.

[2]  W. D. Walters,et al.  Epithelial dysplasia of the uterine cervix in pregnancy. , 1956, American journal of clinical pathology.

[3]  H. Jones,et al.  The significance of basal-cell hyperactivity in cervical biopsies. , 1955, American journal of obstetrics and gynecology.

[4]  A. Hertig,et al.  A debate: what is cancer in situ of the cervix? Is it the preinvasive form of true carcinoma? , 1952, American journal of obstetrics and gynecology.

[5]  A. Hertig,et al.  A study of 135 cases of carcinoma in situ of the cervix at the Free Hospital for Women. , 1949, American journal of obstetrics and gynecology.

[6]  R. Scott,et al.  Atypical hyperplasia of uterine cervix , 1955, Cancer.